- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Dermatology and Skin Diseases
- COVID-19 epidemiological studies
- Olfactory and Sensory Function Studies
- vaccines and immunoinformatics approaches
- Immunodeficiency and Autoimmune Disorders
- Viral Infections and Outbreaks Research
- Rabies epidemiology and control
- Traumatic Ocular and Foreign Body Injuries
- Respiratory and Cough-Related Research
- COVID-19 Pandemic Impacts
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- COVID-19 Clinical Research Studies
- Transgenic Plants and Applications
- Venomous Animal Envenomation and Studies
- IL-33, ST2, and ILC Pathways
Mashhad University of Medical Sciences
2019-2024
Lorestan University of Medical Sciences
2019-2024
STAT6 (signal transducer and activator of transcription 6) is a factor that plays central role in the pathophysiology allergic inflammation. We have identified 16 patients from 10 families spanning three continents with profound phenotype early-life onset immune dysregulation, widespread treatment-resistant atopic dermatitis, hypereosinophilia esosinophilic gastrointestinal disease, asthma, elevated serum IgE, IgE-mediated food allergies, anaphylaxis. The cases were either sporadic (seven...
Background: This study assessed whether a modified immunotherapy schedule for allergic rhinitis could be safe and efficient. Ultra-rush (URIT) rapidly desensitizes patients to aeroallergens. Objective: We aimed develop URIT protocol in 3 days achieve the target dose while observing it improve this situation decrease time maintenance dose. Methods: The was exercised 21 with perennial rhinitis. Premeditations were given prior during injections immunotherapy: pred nisolone, ranitidine,...
Allergic rhinitis (AR) is a common hypersensitivity disease worldwide. Immunotherapy has been performed as the best treatment for years. This study aimed to gene expression pattern of immune system cells following an accelerated rush immunotherapy protocol (ARIT) in patients with AR.Fifteen AR (15-55 years old) resident Mashhad, Iran, positive prick test regional aeroallergens (weed mix, grass tree and Salsola) enrolled this study. All were treated three months 3-day ARIT between July 2015...
Background: It is well established that upper and lower airways are often clumped together when diagnosing treating a disease. This study was designed to determine the prevalence of airway diseases assess effect sociodemographic factors on comorbidity these disorders. Methods: cross-sectional population-based included patients with ages ranging between 15 65 years, who were referred allergy outpatient clinics in various provinces Iran from April September 2020. A modified global Allergy...
Antivenom is a gold-standard treatment for snakebite envenoming. However, adverse reactions to snake antivenom are common in many parts.The aim of this study was evaluate the allergic following intravenous administration sera.This retrospective conducted on snakebites patients referred Rahimi Hospital Khorramabad. The files these were accessed demographic data, snakebite-related provided, clinical presentation and reaction status as result treatment.141 cases investigated, including 73.8%...
Abstract Allergens originated from Salsola kali ( Russian thistle ) pollen grains are one of the most important sources aeroallergens causing pollinosis in desert and semi-desert regions. T-cell epitope-based vaccines (TEV) more effective among different therapeutic approaches developed to alleviate allergic diseases. The physicochemical properties, B as well T cell epitopes Sal k 1 (a major allergen S. were predicted using immunoinformatic tools. A TEV was constructed linkers EAAAK, GPGPG...
Background: In the 21st century, world has been facing several emerging viral epidemics. These viruses are divided into two categories, including and re-emerging viruses. Factors, such as climate change, global warming, some eating habits will have irreversible effects on human, animal, environmental ecosystems. or infectious diseases significant economy health. The peak of this type disease appeared in 1980s with a epidemic called human immunodeficiency (HIV). recurring affected both...