Rui Liang

ORCID: 0000-0003-2267-4885
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Research Areas
  • Asthma and respiratory diseases
  • IL-33, ST2, and ILC Pathways
  • Immunodeficiency and Autoimmune Disorders

University of Hong Kong
2023

Mehul Sharma Daniel Leung Mana Momenilandi Lauren C.W. Jones Lucia Pacillo and 89 more Alyssa James Jill R. Murrell Selket Delafontaine Jesmeen Maimaris Maryam Vaseghi‐Shanjani Kate L. Del Bel Henry Y. Lu Gilbert T. Chua Silvia Di Cesare Oriol Fornés Zhongyi Liu Gigliola Di Matteo Maggie P. Fu Donato Amodio Issan Yee San Tam Gavin S.W. Chan Ashish Sharma Joshua Dalmann Robin van der Lee Géraldine Blanchard-Rohner Susan Lin Quentin Philippot Phillip A. Richmond Jessica J. Lee Allison Matthews Michael Seear Alexandra K. Turvey Rachael L. Philips Terri F. Brown‐Whitehorn Christopher Gray Kosuke Izumi James R. Treat Kathleen H. Wood Justin Lack Asya Khleborodova Julie E. Niemela Xingtian Yang Rui Liang Lin Kui C. S. M. Wong Grace Wing-kit Poon Alexander Hoischen Caspar I. van der Made Jing Yang Koon Wing Chan Jaime S. Rosa Duque Pamela Lee M. Ho Brian Hon‐Yin Chung Huong Thi Minh Le Wanling Yang Pejman Rohani Ali Fouladvand Hassan Rokni‐Zadeh Majid Changi‐Ashtiani Mohammad Miryounesi Anne Puel Mohammad Shahrooei Andrea Finocchi Paolo Rossi Beatrice Rivalta Cristina Cifaldi Antonio Novelli Chiara Passarelli Stefania Arasi Dominique Bullens Kate Sauer Tania Claeys Catherine M. Biggs Emma Morris Sergio D. Rosenzweig John J. O’Shea Wyeth W. Wasserman H. Melanie Bedford Clara D.M. van Karnebeek Paolo Palma Siobhan O. Burns Isabelle Meyts Jean‐Laurent Casanova Jonathan J. Lyons Nima Parvaneh Anh Thi Van Nguyen Caterina Cancrini Jennifer Heimall Hanan Ahmed Margaret L. McKinnon YL Lau Vivien Béziat Stuart E. Turvey

STAT6 (signal transducer and activator of transcription 6) is a factor that plays central role in the pathophysiology allergic inflammation. We have identified 16 patients from 10 families spanning three continents with profound phenotype early-life onset immune dysregulation, widespread treatment-resistant atopic dermatitis, hypereosinophilia esosinophilic gastrointestinal disease, asthma, elevated serum IgE, IgE-mediated food allergies, anaphylaxis. The cases were either sporadic (seven...

10.1084/jem.20221755 article EN cc-by The Journal of Experimental Medicine 2023-03-08
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