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Research Areas
- Asthma and respiratory diseases
- IL-33, ST2, and ILC Pathways
- Immunodeficiency and Autoimmune Disorders
University of Hong Kong
2023
Mehul Sharma
Daniel Leung
Mana Momenilandi
Lauren C.W. Jones
Lucia Pacillo
and 89
more
Alyssa James
Jill R. Murrell
Selket Delafontaine
Jesmeen Maimaris
Maryam Vaseghi‐Shanjani
Kate L. Del Bel
Henry Y. Lu
Gilbert T. Chua
Silvia Di Cesare
Oriol Fornés
Zhongyi Liu
Gigliola Di Matteo
Maggie P. Fu
Donato Amodio
Issan Yee San Tam
Gavin S.W. Chan
Ashish Sharma
Joshua Dalmann
Robin van der Lee
Géraldine Blanchard-Rohner
Susan Lin
Quentin Philippot
Phillip A. Richmond
Jessica J. Lee
Allison Matthews
Michael Seear
Alexandra K. Turvey
Rachael L. Philips
Terri F. Brown‐Whitehorn
Christopher Gray
Kosuke Izumi
James R. Treat
Kathleen H. Wood
Justin Lack
Asya Khleborodova
Julie E. Niemela
Xingtian Yang
Rui Liang
Lin Kui
C. S. M. Wong
Grace Wing-kit Poon
Alexander Hoischen
Caspar I. van der Made
Jing Yang
Koon Wing Chan
Jaime S. Rosa Duque
Pamela Lee
M. Ho
Brian Hon‐Yin Chung
Huong Thi Minh Le
Wanling Yang
Pejman Rohani
Ali Fouladvand
Hassan Rokni‐Zadeh
Majid Changi‐Ashtiani
Mohammad Miryounesi
Anne Puel
Mohammad Shahrooei
Andrea Finocchi
Paolo Rossi
Beatrice Rivalta
Cristina Cifaldi
Antonio Novelli
Chiara Passarelli
Stefania Arasi
Dominique Bullens
Kate Sauer
Tania Claeys
Catherine M. Biggs
Emma Morris
Sergio D. Rosenzweig
John J. O’Shea
Wyeth W. Wasserman
H. Melanie Bedford
Clara D.M. van Karnebeek
Paolo Palma
Siobhan O. Burns
Isabelle Meyts
Jean‐Laurent Casanova
Jonathan J. Lyons
Nima Parvaneh
Anh Thi Van Nguyen
Caterina Cancrini
Jennifer Heimall
Hanan Ahmed
Margaret L. McKinnon
YL Lau
Vivien Béziat
Stuart E. Turvey
STAT6 (signal transducer and activator of transcription 6) is a factor that plays central role in the pathophysiology allergic inflammation. We have identified 16 patients from 10 families spanning three continents with profound phenotype early-life onset immune dysregulation, widespread treatment-resistant atopic dermatitis, hypereosinophilia esosinophilic gastrointestinal disease, asthma, elevated serum IgE, IgE-mediated food allergies, anaphylaxis. The cases were either sporadic (seven...
10.1084/jem.20221755
article
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cc-by
The Journal of Experimental Medicine
2023-03-08
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