A5014978519- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Cardiac Imaging and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Cardiovascular Function and Risk Factors
- Prostate Cancer Treatment and Research
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Medical Imaging and Pathology Studies
- Lung Cancer Research Studies
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Prostate Cancer Diagnosis and Treatment
- Cardiovascular Disease and Adiposity
- Thyroid Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Radiation Dose and Imaging
- Renal cell carcinoma treatment
- Cervical Cancer and HPV Research
- Lanthanide and Transition Metal Complexes
- Adrenal and Paraganglionic Tumors
University of Ferrara
2015-2025
University of Maryland, Baltimore
2021
Harefield Hospital
2020
Imperial College London
2020
Arcispedale Sant'Anna
2004-2017
Lithuanian University of Health Sciences
2016
Centro Hospitalar de Vila Nova de Gaia
2016
Ospedale Sant'Anna
2013-2016
Columbia University Irving Medical Center
2016
St. Anna Hospital
1997
Abstract Purpose Build machine learning (ML) models able to predict pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) in breast cancer (BC) patients based on conventional and radiomic signatures extracted from baseline [ 18 F]FDG PET/CT. Material methods Primary tumor the most significant lymph node metastasis were manually segmented PET/CT of 52 newly diagnosed BC patients. Clinical parameters, NAC semiquantitative PET parameters collected. The standard reference...
Aims There is increasing evidence that stem cell (SC) mobilization to the heart and their differentiation into cardiac cells a naturally occurring process. We sought assess safety feasibility of granulocyte-colony stimulating factor (G-CSF) administration in humans enhance SC left ventricle (LV) injury repair during myocardial infarction (MI).
Pheochromocytoma and paraganglioma (PPGL) have currently only limited treatment options available for patients in the metastatic phase (mPPGL) either post-surgery or inoperable settings. However, these rare tumors overexpress somatostatin receptors can thus be treated with peptide receptor radionuclide therapy (PRRT). We present data about our 10-year experience treating 46 consecutive mPPGL 90Y-DOTATOC 177Lu-DOTATATE.All (20 men 26 women, median age 52 years) showed positive scintigraphic...
Radio-ligand therapy (RLT) with177Lu-PSMA-617 is a promising option for patients with metastatic castration-resistant prostate-cancer (mCRPC). A prospective phase-II study (EUDRACT/RSO,2016-002732-32) on mCRPC ongoing at IRST (Meldola, Italy). total of 9 (median age: 68 y, range: 53⁻85) were enrolled dosimetry evaluation parotid glands (PGs), kidneys, red marrow (RM) and whole body (WB). Folic polyglutamate tablets orally administered as PGs protectors 500 mL 10% mannitol solution was...
Pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) is a strong prognostic factor in breast cancer (BC). The aim of this study was to investigate whether semiquantitative parameters derived from baseline [18F]Fluorodeoxyglucose ([18F]FDG) positron emission computed tomography/computed tomography (PET/CT) could predict pCR NAC and survival outcomes patients affected by different molecular subtypes BC. We retrospectively retrieved the databases two Italian hospitals...
A lyophilized kit formulation for the efficient labelling of lipiodol with generator-produced rhenium-188 is described. The preliminary preparation lipophilic complex bis-(diethyldithiocarbamato)nitrido (188ReN-DEDC) was carried out using a two-vial containing S-methyl-N-methyl-dithiocarbazate, SnCl2 and sodium oxalate in first vial, diethyldithiocarbamate carbonate buffer second vial. After mixing reaction solution lipiodol, 188ReN-DEDC quantitatively extracted retained by this hydrophobic...
Academic journals have published a large number of papers in the therapeutic nuclear medicine (NM) research field last 10 years. Despite this, literature analysis has never before been made to point out interest radionuclides (RNs). For this reason, present study aims specifically analyze output on radiometals from 2008 2018, with intent quantify and identify global trends scientific emphasize interdisciplinary nature field. The data search targeted conventional (131I, 90Y, 177Lu, 188Re,...
[18F]F-FDG (FDG) PET is emerging as a relevant diagnostic and prognostic tool in neuroendocrine neoplasms (NENs), simultaneous decrease [68Ga]Ga-DOTA peptides increase FDG uptake (the “flip-flop” phenomenon) occurs during the natural history of these tumors. The aim this study was to evaluate variations on NEN patients treated with two different schemes radioligand therapy (RLT) correlate them clinical−pathologic variables. A prospective evaluation 108 lesions 56 (33 males 23 females; median...
Our purpose was to evaluate the safety profile and biodistribution behavior in healthy human volunteers of new myocardial perfusion tracer bis[(dimethoxypropylphosphanyl)ethyl]ethoxyethylamine <i>N,N′</i>-bis(ethoxyethyl)dithiocarbamato nitrido technetium(V) (<sup>99m</sup>Tc-N-DBODC). <b>Methods:</b> Ten male were injected with <sup>99m</sup>Tc-N-DBODC under both stress rest conditions. Anterior posterior planar γ-camera images collected at 5, 30, 60, 240, 1,440 min after injection, organ...