A5003299136- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Prostate Cancer Treatment and Research
- Lung Cancer Research Studies
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Prostate Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Breast Cancer Treatment Studies
- Lung Cancer Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Advanced X-ray and CT Imaging
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Cancer Studies
- Lung Cancer Treatments and Mutations
- CNS Lymphoma Diagnosis and Treatment
- MRI in cancer diagnosis
- Salivary Gland Disorders and Functions
- Urologic and reproductive health conditions
University of Ferrara
2021-2024
[18F]F-FDG (FDG) PET is emerging as a relevant diagnostic and prognostic tool in neuroendocrine neoplasms (NENs), simultaneous decrease [68Ga]Ga-DOTA peptides increase FDG uptake (the “flip-flop” phenomenon) occurs during the natural history of these tumors. The aim this study was to evaluate variations on NEN patients treated with two different schemes radioligand therapy (RLT) correlate them clinical−pathologic variables. A prospective evaluation 108 lesions 56 (33 males 23 females; median...
Purpose The aim of the present study was to explore prognostic role 2- deoxy-2-[18F]fluoro-D-glucose PET (FDG PET)/CT in recurrent luminal A and B breast cancer. Materials methods From two institutional databases, we retrospectively retrieved data about cancer patients undergoing FDG PET/CT between 2011 2018 for assessment recurrency. Molecular subtypes were defined based on expression estrogen, progesterone, human epidermal growth factor receptor 2 (HER2)-b receptors proliferation index....
this study aims to explore the prognostic and predictive role of volumetric parameters on [68Ga]Ga-DOTATOC PET/CT in neuroendocrine tumors (NET) patients treated with peptide receptor radionuclide therapy (PRRT).We retrospectively evaluated 39 NET (21 male, 18 female; mean age 60.7 y) within FENET-2016 trial (CTiD:NCT04790708). PRRT was proposed [177Lu]Lu-DOTATOC alone or combined [90Y]Y-DOTATOC. performed at baseline 3 months after PRRT. For each PET/CT, we calculated SUVmax, SUVmean,...
The presence of cervical lymph node metastases (CLNM) at diagnosis is one the most relevant negative prognostic factors in patients with head and neck squamous cell carcinoma (HNSCC). aim this study was to analyse 2-deoxy-2[18F]fluoro-D-glucose (FDG) PET/CT findings for identification primary tumours CLNM a sample affected by HNSCC. Moreover, maximum standardised uptake value (SUVmax) threshold detection estimated. Clinical variables (i.e. smoking alcohol habits), tumour features EBV HPV...
To evaluate the relevance of incidental prostate [18F]FDG uptake (IPU) and to explore potential radiomics machine learning (ML) predict cancer (PCa).We retrieved PET/CT scans with evidence IPU performed in two institutions between 2015 2021. Patients were divided into PCa non-PCa, according biopsy. Clinical PET/CT-derived information (comprehensive radiomic analysis) acquired. Five ML models developed their performance discriminating vs non-PCa was evaluated. Radiomic analysis investigated...
This study aims to the clinical-diagnostic relevance of incidental breast uptake ("incidentaloma") on 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) scan performed for other indications and correlate it with radiological imaging histopathology.We retrospectively evaluated 3675 FDG-PET scans, identifying 43 patients "incidentaloma." Thirty these findings were further investigated clinical examination, mammography (MMX), UltraSound (US) and/or...
Hodgkin Lymphoma (HL) is a malignancy involving lymph nodes and lymphatic system. [18F]F-FDG PET/CT (FDG-PET) imaging routinely used for staging, to assess early chemotherapy response (interim FDG-PET), at the end of treatment (EoT FDG-PET) identification disease recurrence. We present case 39-year-old man treated HL. FDG-PET scans performed after first line therapy (both Interim PET therapy) demonstrated persistent significant mediastinal FDG uptake. The patient was with second but uptake...
A 46-year-old female with Sjögren's syndrome previously treated corticosteroids was referred to our department for suspicious humeral head osteonecrosis. Dual-phase bone scan showed an increased radiotracer distribution in the of left humerus. Nevertheless, whole-body revealed multiple sites heterogeneous skeletal uptake. As lymphoproliferative disorder hypothesized, also based on laboratory examination, F-18 fluorodeoxyglucose positron-emission tomography/computed tomography performed and...