- Intensive Care Unit Cognitive Disorders
- Pancreatic and Hepatic Oncology Research
- Gastric Cancer Management and Outcomes
- Anesthesia and Neurotoxicity Research
- Minimally Invasive Surgical Techniques
- Anesthesia and Sedative Agents
- Pancreatitis Pathology and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Gastrointestinal disorders and treatments
- Optical Coherence Tomography Applications
- Neuroendocrine Tumor Research Advances
- Gallbladder and Bile Duct Disorders
- Gastrointestinal Tumor Research and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Frailty in Older Adults
- Thermal Regulation in Medicine
- Esophageal and GI Pathology
- Vascular anomalies and interventions
- Coronary Interventions and Diagnostics
- Eosinophilic Esophagitis
- Advanced Fluorescence Microscopy Techniques
- S100 Proteins and Annexins
- Renal cell carcinoma treatment
- Sympathectomy and Hyperhidrosis Treatments
- Bariatric Surgery and Outcomes
Massachusetts General Hospital
2009-2025
Harvard University
2006-2025
Brown University
2014-2023
Providence College
2015-2023
Miriam Hospital
2015-2023
Providence VA Medical Center
2022
Rhode Island Hospital
2022
John Brown University
2021
Lifespan
2021
Brigham and Women's Hospital
2006-2011
Endoscopic ultrasound (EUS) may offer a diagnostic tool through the combination of imaging and guided fine-needle aspiration pancreatic cysts. The purpose this investigation was to determine most accurate test for differentiating mucinous from nonmucinous cysts.The results EUS imaging, cytology, cyst fluid biochemical markers were prospectively collected compared in large single-center study (776 patients) using histology or malignant cytology as final standard 198 patients.The mean...
Objectives: Current treatment guidelines do not address the unique health risks or life priorities of aging population with inflammatory bowel diseases (IBD). Patient priority-directed care approaches can facilitate better clinical management for this population. We aimed to explore experiences older adults IBD in relation medical and surgical treatments by investigating factors that influence their decision-making. Methods: conducted qualitative in-depth interviews 22 patients ≥60 years who...
Background: Cognitive impairment is a well-recognized risk factor for delirium. Our goal was to determine whether the level of cognitive performance across nondemented ability spectrum correlated with delirium and gauge importance cognition relative other known factors Methods: The Successful Aging after Elective Surgery study enrolled 566 adults aged ≥70 years scheduled major surgery. Patients were assessed preoperatively daily during hospitalization occurrence using Confusion Assessment...
We evaluated the role of cognitive and brain reserve markers in modifying risk postoperative delirium associated with a pathophysiologic marker. The Successful Aging after Elective Surgery study (SAGES) enrolled 556 adults age ≥70 years without dementia scheduled for major surgery. Patients were assessed preoperatively daily during hospitalization delirium. used C-reactive protein (CRP) as marker inflammation, previously Markers included vocabulary knowledge, education, activities,...
Delirium creates distinct emotional distress in patients and family caregivers, yet there are limited tools to assess the experience. Our objective was develop separate patient caregiver delirium burden instruments test their content construct validity. Two hundred forty-seven 213 caregivers were selected from an ongoing prospective cohort of medical-surgical admissions aged ≥70 years old. New developed used measure subjective experiences in-hospital delirium. severity measured by Confusion...
We demonstrate for the first time that optical coherence tomography (OCT) imaging can reliably distinguish between morphologic features of low risk pancreatic cysts (i.e., pseudocysts and serous cystadenomas) high mucinous cystic neoplasms intraductal papillary neoplasms). In our study fresh pancreatectomy specimens (66) from patients with lesions undergoing surgery were acquired examined OCT. A training set 20 pathology-OCT correlated tissue used to develop criteria differentiating lesions....
Littoral cell angioma is a rare primary vascular neoplasm of the spleen composed blood-filled channels. Typically, littoral presents with splenomegaly caused by multiple small hypoattenuating nodules that show delayed enhancement. We report an unusual case presented as large solitary mass.
Abstract Background Older surgical patients have an increased risk for postoperative complications, driving up healthcare costs. We determined if co‐management of older surgery is associated with outcomes and hospital Methods Retrospective data were collected ≥70 years old undergoing colorectal at a community teaching hospital. Patient compared between those receiving care through the Optimization Senior Care Recovery (OSCAR) program controls who received standard care. Main outcome measures...
Wide range of congenital and acquired cysts that arise from various tissue linings the abdomen are grouped as mesenteric cysts. A non-pancreatic pseudocyst mesentery is an uncommon, pathologic entity, developing secondary to trauma or infection. Awareness imaging features may help radiologists differentiate them other abdominal neoplastic processes prevent unnecessary surgery. We report CT MR a mesentery.
Optical Coherence Tomography (OCT) is an emerging optical technology that has shown great promise for early cancer detection. Using backreflected light to visualize tissue microstructure, OCT can provide information on nuclear size and shape, nuclear-to-cytoplasmic ratio, the organization structure of glands. It also functional information, like blood flow, birefringence, etc. These capabilities could potentially be employed in three ways: as a primary diagnostic test replace biopsy,...
Abstract Background Trauma patients older than 80 years of age have higher mortality rates compared to younger peers. No studies investigated the effectiveness geriatrics comanagement on in general trauma. Methods A retrospective cohort study from 2015 2016 comparing overall and inpatient a trauma (GTC) program versus usual care (UC). Demographic outcome measures were obtained registry at an 11-bed critical unit within 719-bed Level 1 Center. One thousand five hundred seventy two patients,...