Diana Sotelo

ORCID: 0000-0002-5152-9882
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Tryptophan and brain disorders
  • Functional Brain Connectivity Studies
  • Neuroscience and Neuropharmacology Research
  • 3D Printing in Biomedical Research
  • Mental Health Research Topics
  • Sleep and Wakefulness Research
  • Diet and metabolism studies
  • Treatment of Major Depression
  • Antibiotic Resistance in Bacteria
  • Educational Research and Science Teaching
  • Sleep and related disorders
  • Heart Rate Variability and Autonomic Control
  • Mitochondrial Function and Pathology
  • Literacy and Educational Practices
  • Neurotransmitter Receptor Influence on Behavior
  • Medical research and treatments
  • Attention Deficit Hyperactivity Disorder
  • Pluripotent Stem Cells Research
  • Regulation of Appetite and Obesity
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Additive Manufacturing and 3D Printing Technologies
  • Anesthesia and Neurotoxicity Research
  • Neuroscience and Neural Engineering
  • Stress Responses and Cortisol
  • HIV/AIDS Research and Interventions

National Institute on Alcohol Abuse and Alcoholism
2022-2025

National Institutes of Health
2022-2025

The University of Texas at El Paso
2021-2025

Texas Tech University
2024

Texas Tech University Health Sciences Center
2024

Fundación Universitaria María Cano
2015

University of Córdoba
2009

Abstract Motivated behaviors are regulated by distributed forebrain networks. Traditional approaches have often focused on individual brain regions and connections that do not capture the topographic organization of connectivity. We performed co-injections anterograde retrograde tract tracers in rats to provide novel high-spatial resolution evidence elaborate a previously identified closed-loop circuit implicated affective motivational processes. The nodes this include select medial...

10.1101/2025.01.18.633747 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2025-01-19

Importance Sleep and circadian disruptions are highly prevalent in opioid use disorder (OUD) a barrier to successful treatment recovery; yet few objective data available, especially for individuals OUD with agonist therapy. If remain present despite treatment, this information would yield potential new targets adjunctive Objective To systematically investigate different aspects of rest-activity rhythms (RAR), including sleep, physical activity, rhythmicity, brain functional correlates OUD....

10.1001/jamanetworkopen.2024.57976 article EN cc-by-nc-nd JAMA Network Open 2025-02-04

The rewarding effects of stimulant drugs such as methylphenidate (MP) depend crucially on how fast they raise dopamine in the brain. Yet rate drug-induced increases impacts brain network communication remains unresolved. We manipulated route MP administration to generate versus slow increases. hypothesized that would result a differential pattern global connectivity (GBC) association with regional levels D1 receptors, which are critical for drug reward. Twenty healthy adults received...

10.1038/s41386-024-01803-8 article EN cc-by Neuropsychopharmacology 2024-02-07

Ketamine, a noncompetitive NMDA receptor antagonist, has been exclusively used as an anesthetic in medicine and led to new insights into the pathophysiology of neuropsychiatric disorders. Clinical studies have shown that low subanesthetic doses ketamine produce antidepressant effects for individuals with depression. However, its use treatment psychiatric disorders limited due reinforcing high potential diversion misuse. Preclinical focused on understanding molecular mechanisms underlying...

10.1016/j.imed.2022.03.001 article EN cc-by Intelligent Medicine 2022-03-07

Objective: To determine the level of sedentary nature physiotherapy program students during thesecond period 2014 at Maria Cano University Foundat...

10.17151/hpsal.2015.20.2.5 article EN cc-by Hacia la Promoción de la Salud 2015-12-08

Objetivo Determinar la presencia de antibióticos en leches crudas y procesadas el municipio Montería. Materiales métodos Se realizaron tres muestreos con intervalo dos meses, una empresa acopiadora leche ciudad Montería, además, se analizaron muestras pasteurizadas seis marcas comerciales. A todas las les realizó prueba acidez por alcoholimetría, también determinó del antiséptico H2O2 a través KI al 35% V2O5 1% H2SO4 diluido. Posteriormente detecto (Total antibiotic Bio K 331 (BioX...

10.1590/s0124-00642009000400009 article ES Revista de Salud Pública 2009-08-01

The hypothalamus and zona incerta of the brown rat ( Rattus norvegicus ), a model organism important for translational neuroscience research, contain diverse neuronal populations essential survival, but how these are structurally organized as systems remains elusive. With advent novel gene-editing technologies, there has been growing need high-spatial-resolution maps hypothalamic neurochemical cell types to aid in their functional interrogation by virus-directed type-specific gene...

10.1101/2024.10.02.616213 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-10-03

3D bioprinting offers a simplified solution for engineering of brain tissue in-vitro drug discovery or, in-vivo implantation in the future. However, there exists significant amount challenges neural tissues, as these are sensitive cell types to handle via extrusion techniques. We assessed feasibility human progenitor cells (NPC’s) hydrogel lattices using fibrinogen-alginate-chitosan bioink, previously optimized neural-cell growth, and subsequently modified structural-support during printing....

10.2139/ssrn.3991072 article EN SSRN Electronic Journal 2021-01-01
Coming Soon ...