- 3D Printing in Biomedical Research
- Pluripotent Stem Cells Research
- Angiogenesis and VEGF in Cancer
- Microfluidic and Bio-sensing Technologies
- Glioma Diagnosis and Treatment
- Advanced biosensing and bioanalysis techniques
- Regional Development and Innovation
- Viral Infections and Outbreaks Research
- Tissue Engineering and Regenerative Medicine
- Nanowire Synthesis and Applications
- COVID-19 Clinical Research Studies
- bioluminescence and chemiluminescence research
- COVID-19 epidemiological studies
- Neuroscience and Neural Engineering
- Cellular Mechanics and Interactions
- Business, Innovation, and Economy
- CAR-T cell therapy research
- Economic Zones and Regional Development
- Nanofabrication and Lithography Techniques
University of California, San Francisco
2020-2022
University of California, Berkeley
2021-2022
Chan Zuckerberg Initiative (United States)
2021
Chan Zuckerberg Biohub San Francisco
2021
Institute for Neurodegenerative Disorders
2020
National Institutes of Health
2014
National Heart Lung and Blood Institute
2014
Designing smarter anticancer T cells Biological signaling systems can exhibit a large, nonlinear—or “ultrasensitive”—response, which would be useful to engineer into therapeutic allow for better discrimination between cancer and normal tissues. Hernandez-Lopez et al. modified human using two-step mechanism that allowed them kill expressing large amounts of marker protein but not small amount the same protein. A first synthetic receptor recognized antigen with low affinity. That signaled...
Author(s): Crawford, Emily D; Acosta, Irene; Ahyong, Vida; Anderson, Erika C; Arevalo, Shaun; Asarnow, Daniel; Axelrod, Shannon; Ayscue, Patrick; Azimi, Camillia S; Azumaya, Caleigh M; Bachl, Stefanie; Bachmutsky, Iris; Bhaduri, Aparna; Brown, Jeremy Bancroft; Batson, Joshua; Behnert, Astrid; Boileau, Ryan Bollam, Saumya R; Bonny, Alain Booth, David; Borja, Michael Jerico B; Buie, Bryan; Burnett, Cassandra E; Byrnes, Lauren Cabral, Katelyn A; Cabrera, Joana P; Caldera, Saharai; Canales,...
The construction of three-dimensional (3D) microvascular networks with defined structures remains challenging. Emerging bioprinting strategies provide a means patterning endothelial cells (ECs) into the geometry 3D networks, but microenvironmental cues necessary to promote their self-organization cohesive and perfusable microvessels are not well known. To this end, we reconstituted microvessel formation in vitro by thin lines closely packed ECs fully embedded within extracellular matrix...
The relative positioning of cells is a key feature the microenvironment that organizes cell-cell interactions. To study interactions between same or different type, micropatterning techniques have proved useful. DNA Programmed Assembly Cells (DPAC) technique targets adhesion to substrate other using hybridization. most basic operations in DPAC begin with decorating cell membranes lipid-modified oligonucleotides, then flowing them over has been patterned complementary sequences. adhere...
Abstract The construction of three-dimensional (3D) microvascular networks with defined structures remains challenging. Emerging bioprinting strategies provide a means patterning endothelial cells (ECs) into the geometry 3D networks, but microenvironmental cues necessary to promote their self-organization cohesive and perfusable microvessels are unknown. To this end, we reconstituted microvessel formation in vitro by thin lines closely packed ECs fully embedded within extracellular matrix...
The relative positioning of cells is a key feature the microenvironment that organizes cell-cell interactions. To study interactions between same or different type, micropatterning techniques have proved useful. DNA Programmed Assembly Cells (DPAC) technique targets adhesion to substrate other using hybridization. most basic operations in DPAC begin with decorating cell membranes lipid-modified oligonucleotides, then flowing them over has been patterned complementary sequences. adhere...