- Psoriasis: Treatment and Pathogenesis
- Immune cells in cancer
- Cellular Mechanics and Interactions
- Force Microscopy Techniques and Applications
- Lipid Membrane Structure and Behavior
- Dermatology and Skin Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Phytochemical compounds biological activities
- Whipple's Disease and Interleukins
- Supramolecular Chemistry and Complexes
- biodegradable polymer synthesis and properties
- Cold Atom Physics and Bose-Einstein Condensates
- Inhalation and Respiratory Drug Delivery
- RNA modifications and cancer
- Dendrimers and Hyperbranched Polymers
- Click Chemistry and Applications
- melanin and skin pigmentation
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Advanced Materials and Mechanics
- Parasite Biology and Host Interactions
- Conducting polymers and applications
- NF-κB Signaling Pathways
- Cytokine Signaling Pathways and Interactions
- Luminescence and Fluorescent Materials
- Hydrogels: synthesis, properties, applications
Shenzhen University Health Science Center
2025
Southern Medical University
2016-2024
Ganzhou People's Hospital
2024
Nanfang Hospital
2024
Guangdong Ocean University
2018
Xiamen University
2015-2016
Shenzhen University
2013-2015
Ministry of Health and Welfare
1995
Abstract Incorporation of small reactive moieties, the reactivity which depends on externally imposed load (so‐called mechanophores) into polymer chains offers access to a broad range stress‐responsive materials. Here, we report that polymers incorporating spirothiopyran (STP) manifest both green mechanochromism and load‐induced addition reactions in solution solid. Stretching macromolecule containing colorless STP converts it thiomerocyanine (TMC), mechanically activated thiolate moiety...
Polystyrene microplastics (PS-MPs) are new types of environmental pollutant that have garnered significant attention in recent years since they were found to cause damage the human respiratory system when inhaled. The pulmonary fibrosis is one serious consequences PS-MPs inhalation. However, impact and underlying mechanisms on not clear. In this study, we studied potential lung toxicity PS-MPs-developed by long-term intranasal inhalation PS-MPs. results showed after exposing PS-MPs, lungs...
Interleukin-37 (IL-37), a new member of IL-1 family cytokine, is recently identified as natural inhibitor innate immunity. This study aimed to measure the peripheral blood mononuclear cells (PBMCs) and serum levels IL-37 in patients with systemic lupus erythematosus (SLE) investigate its role SLE, including correlation disease activity, organ disorder regulation inflammatory cytokines. The expressions mRNAs PBMCs 66 SLE were measured by real-time polymerase chain reaction (RT-PCR)...
Interleukin-37 (IL-37) has been known to play an immunosuppressive role in various inflammatory disorders, but whether it participates the regulation of pathogenesis ankylosing spondylitis (AS) not investigated. Here, we examined serum levels IL-37 and its clinical association AS, explored anti-inflammatory effects on peripheral blood mononuclear cells (PBMCs) from AS patients. The mRNA IL-37, TNF-α, IL-6, IL-17, IL-23 PBMCs their concentrations 46 patients were by real-time polymerase chain...
Background Intreleukin-37 (IL-37), a member of IL-1 family, is primarily an anti-inflammatory cytokine, which reduces systemic and local inflammation. However, the expression role IL-37 in Graves' disease (GD) remains unknown. This study aims to measure levels serum peripheral blood mononuclear cells (PBMCs) patients with examine its association activity. Furthermore, we investigate effect on proinflammatory cytokines involved pathogenesis GD. Methods The expressions IL-37, TNF-α, IL-6,...
Abstract Introduction Our objective in the present study was to determine signaling pathway of interleukin 10 (IL-10) for modulating IL-17 expression macrophages and importance this mediation collagen-induced arthritis (CIA). Methods IL-10-knockout (IL-10 −/− ) mice wild-type (WT) were immunized with chicken type II collagen (CII) induce arthritis. The levels retinoid-related orphan receptor γt (RORγt) joint tissues IL-10 WT analyzed by enzyme-linked immunosorbent assay, quantitative RT-PCR...
Abstract Incorporation of small reactive moieties, the reactivity which depends on externally imposed load (so‐called mechanophores) into polymer chains offers access to a broad range stress‐responsive materials. Here, we report that polymers incorporating spirothiopyran (STP) manifest both green mechanochromism and load‐induced addition reactions in solution solid. Stretching macromolecule containing colorless STP converts it thiomerocyanine (TMC), mechanically activated thiolate moiety...
To gain further insights into the molecular basis of Sulforaphane (SF) mediated retinal pigment epithelial (RPE) 19 cell against oxidative stress, we investigated effects SF on regulation gene expression a global scale and tested whether can endow RPE cells with ability to resist apoptosis. The data revealed that after exposure H2O2, viability was increased in pretreated compared not treated SF. Microarray analysis significant changes 69 genes 6 hours treatment. Based functional relevance,...
Acute kidney injury (AKI) often occurs as a result of ischemia-reperfusion (IR). Previous studies have demonstrated that inflammation is an important contributor to AKI. Atorvastatin (ATO) possesses anti‑inflammatory properties and has been exert protective effects against renal IR (IRI). However, the underlying mechanism requires further study. In present study, rat model IRI was successfully established. Consistent with results previous ATO significantly attenuated IRI, which supported by...
So wie mechanischer Druck schöne Klänge auf einer Geige erzeugt, kann die mechanische Belastung von Polymeren zu interessanten chemischen Reaktionen führen. In der Zuschrift S. 3092 ff. stellen W. Weng et al. ein Spirothiopyran-Polymer vor, das bei Einwirkung mechanischen Kraft hellgrün leuchtet und Quervernetzung eingeht. Zwei charakteristische Antworten eine sind in einem einzigen reaktiven Molekül kombiniert. Sauerstoffentwicklung Metalloide Cluster Graphenoxid
Based on two-level atomic theory and Doppler Effect, the laser collimation of Cr atoms with 3-D simulation analysis has been studied in this paper. By analyzing force chromium atom, a theoretical model is built accurate trajectory cooling field achieved. The final distribution different parameters also described.