A5007932941- Muscle Physiology and Disorders
- Muscle activation and electromyography studies
- Nutrition and Health in Aging
- Muscle metabolism and nutrition
- Cardiovascular and exercise physiology
- Cerebral Palsy and Movement Disorders
- Diabetes Management and Research
- Shoulder Injury and Treatment
- Advanced Sensor and Energy Harvesting Materials
- Hormonal and reproductive studies
- Adipose Tissue and Metabolism
- Diabetes Treatment and Management
- Ergonomics and Musculoskeletal Disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Children's Physical and Motor Development
- Biotin and Related Studies
- Neurogenetic and Muscular Disorders Research
- Reproductive Biology and Fertility
- Erythropoietin and Anemia Treatment
- Tendon Structure and Treatment
- Cardiovascular Function and Risk Factors
- Iron Metabolism and Disorders
- Spaceflight effects on biology
- Peripheral Nerve Disorders
- Nutritional Studies and Diet
University of Padua
2020-2025
University of Brescia
2023-2024
University of Urbino
2020-2021
University of Trieste
2007
Electrophysiological alterations of the neuromuscular junction (NMJ) and motor unit potential (MUP) with unloading are poorly studied. We aimed to investigate these aspects underlying molecular mechanisms short-term active recovery (AR). Eleven healthy males underwent a 10-day unilateral lower limb suspension (ULLS) period, followed by 21-day AR based on resistance exercise. Quadriceps femoris (QF) cross-sectional area (CSA) isometric maximum voluntary contraction (MVC) were evaluated....
Abstract Short‐term unloading experienced following injury or hospitalisation induces muscle atrophy and weakness. The effects of exercise have been scarcely investigated. We investigated the functional molecular adaptations to a resistance training (RT) programme short‐term unloading. Eleven males (22.09 ± 2.91 years) underwent 10 days unilateral lower limb suspension (ULLS) followed by 21 knee extensor RT (three times/week). Data collection occurred at Baseline (LS0), after ULLS (LS10)...
To non-invasively test the hypothesis that (a) short-term lower limb unloading would induce changes in neural control of force production (based on motor units (MUs) properties) vastus lateralis muscle and (b) possible are reversed by active recovery. Ten young males underwent 10 days unilateral suspension (ULLS) followed 21 During ULLS, participants walked exclusively crutches with dominant leg suspended a slightly flexed position (15–20 degrees) contralateral foot raised an elevated shoe....
Prior evidence has shown that neural factors contribute to the loss of muscle force after skeletal disuse. However, little is known about specific mechanisms altered by Persistent inward current (PIC) an intrinsic property motoneurons responsible for prolonging and amplifying synaptic input, proportionally level neuromodulation, thus influencing motoneuron discharge rate production. Here, we hypothesized short-term unilateral lower limb suspension (ULLS) would reduce neuromodulatory input...
Effects of streptozotocin (STZ) — diabetes and insulin treatment on the functioning pituitary-testicular axis during sexual maturation was studied. Prepubertal (30 days old) pubertal (50 male Wistar rats were made diabetic by a single injection STZ. A group given (3U/100 g b.wt./day in 2 equally divided doses), 3 after STZ treatment. all groups killed postnatal 51 71, respectively. STZ-diabetes caused marked reduction serum LH, FSH, prolactin, testosterone testicular interstitial fluid as...
Growing evidence of impaired skeletal muscle health in people with type 1 diabetes points toward the presence a mild myopathy this population. However, myopathic condition is not yet well characterised and often overlooked, even though it might affect whole-body glucose homeostasis development comorbidities. This study aimed to compare adaptations changes glycaemic control after 12 weeks combined resistance aerobic (COMB) training between healthy controls, determine whether can...
High-Density surface Electromyography (HD-sEMG) is the most established technique for non-invasive analysis of single motor unit (MU) activity in humans. It provides possibility to study central properties (e.g., discharge rate) large populations MUs by their firing pattern. Additionally, spike-triggered averaging, peripheral such as conduction velocity can be estimated over adjacent regions muscles and tracked across different recording sessions. In this tutorial, we guide reader through...
The effects of muscle disuse on the propagation action potentials along units, a key process for effective activation and force production, remain poorly understood. This study aimed to investigate changes in potential identify biological factors influencing these following unilateral lower limb suspension (ULLS) active recovery (AR). Eleven young male participants underwent 10 days ULLS followed by 21 AR based resistance exercise. Maximal knee extensor muscles (MVC), High-Density surface...
Background: Achilles tendinopathy (AT) affects ca. 10 million recreational runners in Europe; the practice of hyaluronic acid (HA) infiltration is being increasingly adopted. The aim this pilot study was to monitor effects a three-local time-spaced injections regimen HA treatment AT middle-aged combining for first time viscoelastometric, biochemical, and functional methodologies with routine clinical examinations. Methods: Eight male (Age 49.3 ± 3.9), diagnosed unilateral AT, were given...
Abstract The role of N‐glycosylation in the myogenic process remains poorly understood. Here, we evaluated impact inhibition by Tunicamycin (TUN) or phosphomannomutase 2 ( PMM2 ) gene knockdown, which encodes an enzyme essential for catalyzing early step pathway, on C2C12 myoblast differentiation. effect chronic treatment with TUN tibialis anterior (TA) and extensor digitorum longus (EDL) muscles WT MLC/mIgf‐1 transgenic mice, overexpress muscle Igf‐1Ea mRNA isoform, was also investigated....
Plant-based proteins are generally characterised by lower Indispensable Amino Acid (IAA) content, digestibility, and anabolic properties, compared to animal-based proteins. However, they environmentally friendlier, wider consumption is advocated. Older adults have higher dietary protein needs prevent sarcopenia, a disease marked an accelerated loss of muscle mass function. Given the environmental footprint plant-based importance optimising quality among older adults, this paper aims assess...
Prolactin (PRL) binding to Leydig cells in prepubertal and pubertal streptozotocin (STZ)-diabetic insulin-treated rats was studied. Prepubertal (30-day-old) (50-day-old) were made diabetic by single injection of STZ (120 100 mg/kg b.wt, respectively). After 3 days administration, a group given insulin injections subcutaneously (3 U/100 g b.wt/day 2 equally divided doses). Animals groups killed on postnatal 51 71, respectively. Age-dependent increase serum testosterone, PRL levels receptors...
ABSTRACT To clarify the spawning seasonal dynamics of common carp (Cyprinus carpio) in northeast Italy, female fish were collected monthly from July 2002 to June 2003. The gonadosomatic index (GSI), histomorphology, 17β-estradiol serum concentration, and relative fecundity compared. Between March-April May-June, statistically significant differences found GSI, 17β-estradiol, fecundity. Intermediate multispawner stages by histological analysis specimens caught July-August May-June Final...
Introduction: Mounting evidence suggests that motoneuron and neuromuscular junction (NMJ) degeneration, muscle fiber denervation loss of motor units contribute to wasting weakness in old age. However, these aspects are still poorly investigated humans. This study aimed at comparing the system integrity function young older adults, with particular focus on NMJ unit potential (MUP) characteristics. We hypothesized individuals would present altered electrophysiological properties innervation...
Type 1 diabetes (T1D) is a contributing factor in alterations skeletal muscle health. It has been attributed to accelerated ageing (Monaco et al., 2019), and the molecular are also associated with impaired adaptations physical exercise (Minnock 2022). However, there no evidence about consequences of this condition on behaviour individual motor units (MUs), despite them being effectors contractile stimulus coming from nervous system via modulation their recruitment discharge activity. This...