A5018364516- Fungal Biology and Applications
- Mycorrhizal Fungi and Plant Interactions
- Plant nutrient uptake and metabolism
- Fungal and yeast genetics research
- Cancer survivorship and care
- Plant Physiology and Cultivation Studies
- Plant Pathogens and Fungal Diseases
- Legume Nitrogen Fixing Symbiosis
- Ubiquitin and proteasome pathways
- Phytochemicals and Antioxidant Activities
- Phytochemistry and Bioactivity Studies
- Plant-Microbe Interactions and Immunity
- Childhood Cancer Survivors' Quality of Life
- Muscle Physiology and Disorders
- Fermentation and Sensory Analysis
- Vitamin C and Antioxidants Research
- Dietary Effects on Health
- Erythrocyte Function and Pathophysiology
- Muscle metabolism and nutrition
- Endoplasmic Reticulum Stress and Disease
- Flowering Plant Growth and Cultivation
- Plant Disease Resistance and Genetics
- Glycosylation and Glycoproteins Research
- Plant tissue culture and regeneration
- Diet and metabolism studies
University of Urbino
2012-2025
University of Florence
2021
University of Ferrara
2021
Free University of Bozen-Bolzano
2021
University of Bologna
2021
University of Pavia
2021
Fondazione IRCCS Istituto Nazionale dei Tumori
2021
Tuber magnatum, an ascomycetous fungus and obligate ectomycorrhizal symbiont, forms hypogeous fruit bodies, commonly called Italian white truffles. The diversity of bacterial communities associated with T. magnatum truffles was investigated using culture-independent -dependent 16S rRNA gene-based approaches. Eighteen were classified in three groups, representing different degrees ascocarp maturation, based on the percentage asci containing mature spores. culturable fraction (4.17 +/- 1.61) x...
The microbial community associated with ascocarps of the ectomycorrhizal fungus Tuber borchii Vittad. was studied by both cultivation and direct extraction bacterial 16S rRNA gene (rDNA) sequence approaches. inner part six T. ascoma collected in North-Central Italy used to establish a culture collection extract total genomic DNA obtain library rDNAs representative truffle community. Most isolates were affiliated gamma-Proteobacteria, mainly Fluorescent pseudomonads; some members...
Abstract Results are presented that were obtained on the geographic traceability of white truffle Tuber magnatum Pico. Solid‐phase microextraction coupled to gas chromatography/mass spectrometry (SPME‐GC/MS) was employed characterize volatile profile T . produced in seven geographical areas Italy. The main components fraction identified using SPME‐GC/MS. Significant differences proportion constituents from truffles different detected. results suggest that, besides genetic factors,...
This study aimed to evaluate the cardiometabolic effects of a home-based lifestyle intervention (LI) in breast cancer survivors (BCSs) during COVID-19 lockdown. In total, 30 BCSs (women; stages 0–II; non-metastatic; aged 53.5 ± 7.6 years; non-physically active; normal left ventricular systolic function) with risk factor for recurrence underwent 3-month LI based on nutrition and exercise. Anthropometrics, Mediterranean diet adherence, physical activity level (PAL), cardiorespiratory fitness...
Mitochondrial dysfunction and oxidative stress are central mechanisms in the progression of neurodegenerative diseases. This study first evaluated toxicity Q-Der (Q10-diacetate), a derivative Coenzyme Q10, HT22 hippocampal neurons under normal conditions. cells were treated with at 2.5, 5 10 µM without rotenone. superoxide production (Mitosox), gene expression (via qRT-PCR), protein levels Western blot) measured. Morphological analyses performed using transmission (TEM) scanning (SEM)...
ABSTRACT Insulin‐like growth factor‐1 (IGF‐1) is critical for tissue and development. The IGF‐1 gene contains six exons due to alternative splicing three different isoforms might be produced: the IGF‐1Ea, Eb, Ec prohormones (proIGF‐1s). These proIGF‐1s share same mature sequence, which responsible receptor binding but differ in their carboxy‐terminal extensions called Ea‐, Eb‐, Ec‐peptides. Several lines of evidence indicate that E‐peptides control intracellular localization maturation....
Growing evidence of impaired skeletal muscle health in people with type 1 diabetes points toward the presence a mild myopathy this population. However, myopathic condition is not yet well characterised and often overlooked, even though it might affect whole-body glucose homeostasis development comorbidities. This study aimed to compare adaptations changes glycaemic control after 12 weeks combined resistance aerobic (COMB) training between healthy controls, determine whether can...
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The aim of this study was to conduct a molecular and biochemical characterization compare the antioxidant antiproliferative activities four <i>Ganoderma</i> isolates belonging <i>Ganoderma lucidum</i> (Gl-4, Gl-5) resinaceum</i> (F-1, F-2) species. identification performed by ITS IGS sequence analyses enzymatic proteomic approaches. activity ethanolic extracts compared three different methods their flavonoid contents were also analyzed high-performance liquid...
Abstract Background Breast cancer (BC) is the most common invasive in women, and exercise can significantly improve outcomes of BC survivors. MoviS (Movement Health Beyond Care) a randomized controlled trial aimed to evaluate potential health benefits proper nutritional habits. This study aims assess efficacy aerobic training improving quality life (QoL) health-related factors high-risk BC. Methods One hundred seventy-two survivor aged 30–70 years, non-metastatic, stage 0–III, non-physically...
Abstract Translational research for the evaluation of physical activity habits and lifestyle modifications based on nutrition exercise has recently gained attention. In this study, we evaluated effects serum samples obtained before after a 12-week home-based intervention in breast cancer survivors terms modulation tumorigenic potential cells. The proposed work consisted educational counselling nutritional behaviors 12 weeks structured exercise. Triple-negative cell line MDA-MB-231 was...
Previous studies on Tuber borchii fruit bodies in early maturation stages suggested a role of bacteria sporocarp structural modifications. In order to verify this hypothesis, the present study we investigated by means microbial and ultrastructural approaches, bacterial population T. sporocarps from intermediate phases advanced decomposition stages, paying particular attention chitinolytic cellulolytic their relationships with ascii ascospores. We found that Pseudomonas fluorescens...
Insulin-like growth factor-1 (IGF-1) is synthesised as a prohormone (proIGF-1) requiring enzymatic activity to yield the mature IGF-1. Three proIGF-1s are encoded by alternatively spliced IGF-1 mRNAs: proIGF-1Ea, proIGF-1Eb and proIGF-1Ec. These have common sequence but different E-domains. The structure of E-domains has not been resolved, their molecular functions still unclear. Here, we show that Intrinsically Disordered Regions distinct regulatory on production. In particular, identified...
The present work aimed to investigate whether exposure static magnetic field (SMF) and extremely low frequency (ELF-MF) can induce biomolecular changes on Tuber borchii hyphal growth. mycelium was exposed for 1 h 3 consecutive days a SMF of 300 mT or an ELF-MF 0.1 50 Hz. Gene expression biochemical analyses were performed. In mycelia ELF-MF, some genes involved in growth, investigated using quantitative real-time polymerase chain reaction, upregulated, the activity many glycolytic enzymes...
The insulin-like growth factor-1 (IGF-1) signaling pathway is crucial for the regulation of and development. correct processing IGF-1Ea prohormone (proIGF-1Ea) IGF-1 receptor (IGF-1R) peptide precursor requires proper N-glycosylation. Deficiencies N-linked glycosylation lead to a clinically heterogeneous group inherited diseases called Congenital Disorders Glycosylation (CDG). impact N-glycosylation defects on IGF-1/IGF-1R components largely unknown. In this study, using dermal fibroblasts...