A5062462731- Anesthesia and Pain Management
- Spine and Intervertebral Disc Pathology
- Shoulder Injury and Treatment
- Nausea and vomiting management
- Cardiac, Anesthesia and Surgical Outcomes
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Peripheral Nerve Disorders
- Pain Management and Opioid Use
- Gastrointestinal disorders and treatments
- Esophageal Cancer Research and Treatment
- Pain Mechanisms and Treatments
- Spinal Hematomas and Complications
- Neurosurgical Procedures and Complications
- Aluminum Alloys Composites Properties
- Nerve Injury and Rehabilitation
- Tracheal and airway disorders
- Tumors and Oncological Cases
- Blood transfusion and management
- Pneumothorax, Barotrauma, Emphysema
- Gastrointestinal Tumor Research and Treatment
- Surgical Simulation and Training
- Cancer-related gene regulation
- Pain Management and Treatment
Nagoya University Hospital
2016-2024
Nagoya University
2011-2023
Nagoya City University
2002-2017
Nagoya Medical Center
2017
Komatsu (Japan)
2008-2015
Aichi Medical University
2006-2009
Hirosaki University
2008
Higashi Osaka City General Hospital
2007
RIKEN Center for Brain Science
2004
Mizuho (Japan)
2002
Background: Recently, a vertebrate securin [pituitary tumor transforming gene (PTTG) in humans] has been identified that inhibits sister chromatid separation and is involved malignant transformation tumorigenesis. Abundance of this protein would disrupt cell division, generate chromosomal instability thereby increase susceptibility to acquisition further mutations during subsequent division. Esophageal cancer disease with poor prognosis early local invasion lymph node metastasis. It...
Summary Thoracic interfascial plane blocks are effective for post‐mastectomy acute analgesia. However, their effects on chronic pain uncertain. We randomly allocated 80 women equally to pectoral nerve‐2 (PECS 2) block or serratus block. The reduced the rate of moderate severe from 13/40 (33%) with 4/40 (10%), p = 0.03, adjusted odds ratio (95%CI) 0.23 (0.07–0.80), 0.02. rates pain‐free at six postoperative months were indeterminate, 10/40 (25%) after vs. 19/40 (48%) block, 0.06, 2.9...
Cell cycle progression is monitored by checkpoint mechanisms to ensure the integrity of genome and fidelity sister chromatid separation. Failure such functions results in genomic instability, a condition that predisposes cells neoplastic transformation tumor progression. Recently, Scolnick Halazonetis defined new mitotic acts at prophase delays chromosome condensation response stress, identified gene, named with FHA ring finger (Chfr), seems be required for delaying human cells. In present...
Several types of quadratus lumborum block (QLB) are used for postoperative analgesia and believed to be effective against both somatic visceral pain via a local anesthetic (LA) effect in the paravertebral space (PVS). However, it remains unclear whether all QLB techniques result LA spread into PVS. We hypothesized that administered intramuscular would investigated sensory area QLB.This volunteer study included 5 healthy men 1 woman, with no previous medical history. Intramuscular lateral...
This study aimed to describe and assess the accuracy feasibility of a novel technique for ultrasound-guided maxillary nerve block using lateral pterygoid plate (LPP) approach via pterygopalatine fossa (PPF) in soft cadaveric model.Ten cadavers were studied. The curved array ultrasound transducer probe was applied over 1 side face open-mouth posture. It placed transversely below zygomatic arch identifying border tuberosity LPP. We tilted curve from caudal cranial direction until uppermost...
Abstract Background β-catenin is a multifunctional protein involved in two apparently independent processes: cell-cell adhesion and signal transduction. Wnt signaling pathway that regulates cellular differentiation proliferation. In this study, we investigated the expression pattern of cyclin D1 using immunohistochemistry searched for mutations exon 3 gene Axin esophageal squamous cell carcinoma. Materials methods Samples were obtained from 50 cancer patients. Immunohistochemical staining...
Abstract BACKGROUND DNA fragmentation factor 45 ( DFF45 )/inhibotor of caspase activated DNAse (ICAD) forms a complex with DFF40/CAD and inhibits its cleaving function during apoptosis. also functions as chaperone for native DFF40 is necessary function. It has been indicated that defects in the apoptotic pathway may exist neoplastic cells. METHODS The authors investigated mRNA expression series 46 esophageal squamous cell carcinoma (ESCC) specimens using polymerase chain reaction...
Although spinal cord stimulation has been reported to be effective for controlling neuropathic pain in diabetic neuropathy, it rarely investigated other peripheral neuropathies. We describe, the first time, efficacy of refractory a patient with transthyretin Val30Met associated familial amyloid polyneuropathy (FAP ATTR Val30Met). A 72-year-old man was diagnosed as having FAP when he 70 years old. He had complained burning distal portion his bilateral lower limbs since 69 Because conventional...
We aimed to describe a novel technique of ultrasound-guided selective mandibular nerve block with lateral pterygoid plate (LPP) approach and assess its feasibility accuracy in soft cadaver model.Ten cadavers were studied. A curved array ultrasound transducer was applied over 1 side the face cadaver, an open-mouth position. The placed transversely below zygomatic arch tilted caudal-to-cranial direction identify boundary LPP. needle inserted in-plane, anterior-to-posterior direction, into...
We previously reported an approach to ultrasound-guided thoracic paravertebral block (USG-TPVB) that used a transverse image of the space (TPVS) and in-plane needling.1 In this technique, we aimed position needle tip into lateral edge TPVS between internal intercostal membrane parietal pleura. Successful injection is confirmed by observing pleura being pressed down ventrally local anesthetic. However, steric spread anesthetic in has been unclear.
Abstract Background Anal and perineum pain caused by malignant tumor invasion is often difficult to control with opioids. Continuous sacral epidural ethanol injection therapy less likely cause bladder rectal disturbances, making it a suitable treatment option for patients preserved voiding function. Case presentation A 45-year-old woman multiple metastases of pheochromocytoma suffered severe anal that worsened, especially when sitting, was unresponsive opioid rescue therapy. With her NRS...