A5024214588- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Laser Applications in Dentistry and Medicine
- Ovarian function and disorders
- Bee Products Chemical Analysis
- Wound Healing and Treatments
- Tendon Structure and Treatment
- Testicular diseases and treatments
- Genital Health and Disease
- Effects and risks of endocrine disrupting chemicals
- Curcumin's Biomedical Applications
- Hormonal and reproductive studies
- Selenium in Biological Systems
- Vitamin C and Antioxidants Research
- COVID-19 and healthcare impacts
- Electrospun Nanofibers in Biomedical Applications
- COVID-19 Impact on Reproduction
- Tissue Engineering and Regenerative Medicine
- Caveolin-1 and cellular processes
- Medical and Biological Ozone Research
- Reproductive System and Pregnancy
- Vitamin D Research Studies
- Nanocomposite Films for Food Packaging
- Plant Toxicity and Pharmacological Properties
- Glioma Diagnosis and Treatment
Islamic Azad University Medical Branch of Tehran
2017-2024
Shahid Beheshti University of Medical Sciences
2019-2024
University of Saskatchewan
2022-2024
Islamic Azad University, Science and Research Branch
2022
Islamic Azad University, Tehran
2020
Tarbiat Modares University
2019
Shahid Beheshti University
2009
To evaluate the incidence of apoptosis within testes patients who died from severe acute respiratory syndrome coronavirus 2 (COVID-19) complications, testis tissue was collected autopsies COVID-19 positive (n = 6) and negative men 6). They were then taken for histopathological experiments, RNA extraction, to examine expression angiotensin-converting enzyme (ACE2), transmembrane protease, serine (TMPRSS2), BAX, BCL2 Caspase3 genes. Reactive oxygen species (ROS) production glutathione...
Ovarian aging is related to the reduction of oocyte quality and ovarian follicles reservation leading infertility.Vitamin C a natural antioxidant which may counteract with adverse effects in ovary.The aim this study was evaluate possible effect vitamin on NMRI mice according stereological study.In experimental study, 36 adult female (25-30 g) were divided into two groups: control C. Vitamin (150 mg/kg/day) administered by oral gavage for 33 weeks.Six animals each group sacrificed week 8, 12,...
The aim of the present study was to examine effects low-level laser therapy (LLLT) on tibia streptozotocin-induced diabetic (STZ-D) rats.LLLT has been found accelerate fracture healing in animals. Diabetes mellitus decreases bone volume and its biomechanical parameters.Twenty rats were divided randomly into four groups. Rats first two groups administrated a single injection STZ induce diabetes, while animals 3 4 given sham distilled water. right 1 2 treated with He-Ne (632.8 nm, 10 mW) 28.6...
Background/Aim: The aim of this study was to evaluate the potential and significant applications Sertoli cells (SCs) transplantation, explore effect transplantation on spermatogenesis process, in azospermic mice.Methods: In study, we utilized 18 adult mice (28-30 g), divided into four experimental groups: (1) control, (2) vehicle (DMSO 2%) (10 µl) (3) busulfan (4) busulfan+ SCs (1×104 cells/μL).SCs were isolated from testis 4-week-old mouse after using anesthetics, 10 μl suspension cells/μL)...
The spermatogenesis is temperature-dependent and heat stress have destructive effects on reduces sperm quality. Sixteen adult mice were allocated to two groups: hyperthermia control groups. Scrotal was induced by water bath with 43°C for 30 min. Then, the spermatozoon isolated through tail region of epididymis parameters analysis. testicular tissues taken stereological studies, hormonal assay, TUNEL assay molecular studies. We found a marked decrease in serum testosterone level scrotal as...
The current study was conducted to assess the relationship between testicular cells in spermatogenesis, through which production of healthy and mature sperm is essential. However, it seems necessary obtain more information about three-dimensional pattern testis arrangement, directly related function after induction diabetes. Twelve adult mice (28-30 g) were assigned into two experimental groups: (1) control (2) diabetic (40 mg/kg STZ). epididymal collected from tail epididymis testes samples...
Cell death is a biologically uncontrollable and regulated process associated with human diseases which usually occur in response to oxidative stress that activates signalling pathways multiple forms can therefore contribute diseases. Thus, the current study aims evaluate pathway involved cell after testicular hyperthermia. For this purpose, 32 mice were equally divided into four groups; I: Control; II, III IV, Scrotal hyperthermia testes are exposed water at 43°C for 20 min every other day,...
Animal models of azoospermia are very applicable when evaluating new treatment methods for research purposes. The present study aimed to compare induction in mice using busulfan or hyperthermia. To do this, about 36 adult male (28–30 g) were included into three experimental groups randomly (n = 12): control, (injected by a single dose 40 mg/kg intraperitoneally) and hyperthermia (exposure temperature 43°C every other day 5 weeks). Animals preserved 35 70 days following interventions then...
Background: Chemotherapeutic agents such as cyclophosphamide and busulfan have been shown to a negative impact on the spermatogenesis process. Based this fact, objective of study was investigate effects edaravone in busulfan-induced mice. Methods: Forty adult male mice were equally divided into four groups: 1) control, 2) edaravone, 3) busulfan, 4) + edaravone. Then, sperm parameters, histopathological examinations, serum levels testosterone, follicle-stimulating hormone (FSH), luteinizing...
Objective: The effects of low-level laser therapy (LLLT) on a bone defect model in streptozotocin-induced diabetic (STZ-D) rats was examined. Background Data: LLLT accelerates fracture repair healthy animals, but its effect animals is unclear. Methods: Twenty-eight were divided into five groups: 1 (diabetes, no LLLT), 2 high dose), 3 low 4 (no diabetes, and 5 dose) Diabetes induced by single injection STZ groups 1, 2, 3. A made the right tibia all groups. 3, treated with (890 nm, 70 W, 3000...
Objective: The effect of light therapy (LT) on surgically created partial osteotomy in streptozotocin (STZ)-induced diabetic rats was examined. Background Data: LT has been shown to enhance bone repair healthy human and animal models. Materials Methods: Forty male were divided into groups 1 5. Diabetes induced 1, 2, 3 using an intraperitoneal injection STZ. All maintained for 30 days after STZ injection. Under general anesthesia sterile conditions, a transversal standardized made the...
Busulfan is an anticancer drug, which causes the apoptosis germ cells and azoospermia in humans animals. Abnormal morphology of spermatozoa related to male infertility. The sperm evaluation size, shape appearance characteristics should be assessed by carefully observing a stained sample under microscope. Evaluation has been considered as one most important factors for successful fertilization determining quality. mice were assigned tow experimental groups: control busulfan. Each group...
Polycystic ovary syndrome (PCOS) is a common and multifactorial disease associated with female factor infertility. Ulmus minor bark (UMB) one of the medicinal plants used in Persian folklore as fertility enhancer. In current study, we aimed to elucidate effect UMB hydro-alcoholic extract on histological parameters testosterone condition an experimental model PCOS rats.Thirty rats were randomly divided into five groups: (1) control, (2) vehicle, (3) PCOS/50 mg [6 mg/kg dehydroepiandrosterone...
Busulfan (BSU) is a chemotherapeutic drug that can cause subfertility or sterility in males. We investigated the effects of adipose tissue-derived mesenchymal stem cells (AT-MSC) conditioned medium (CM) (AT-MSC-CM) on histopathological and molecular characteristics mouse testes exposed to BSU using stereology. used adult male mice divided randomly into five groups: control, Dulbecco's modified Eagle's (DMEM), dimethyl sulfoxide (DMSO), BSU, + CM. Thirty-five days following injection, sperm...