- Zebrafish Biomedical Research Applications
- Bioactive natural compounds
- Bioactive Compounds and Antitumor Agents
- Heavy Metal Exposure and Toxicity
- Effects and risks of endocrine disrupting chemicals
- Platelet Disorders and Treatments
- Microbial Natural Products and Biosynthesis
- Marine Sponges and Natural Products
- Environmental Toxicology and Ecotoxicology
- Natural Antidiabetic Agents Studies
- 3D Printing in Biomedical Research
- Berberine and alkaloids research
- Aquaculture disease management and microbiota
- Sirtuins and Resveratrol in Medicine
- Pluripotent Stem Cells Research
- Adipose Tissue and Metabolism
- Saffron Plant Research Studies
- Eicosanoids and Hypertension Pharmacology
- Hematopoietic Stem Cell Transplantation
Shandong Academy of Sciences
2018-2024
Qilu University of Technology
2018-2024
Shandong First Medical University
2022
Shandong University
2022
Psoralen toxicity is an issue of wide concern. However, assay for psoralen-induced developmental has not been reported to date. Moreover, the underlying mechanism unclear. Therefore, this study attempted develop a in zebrafish embryos/larvae. treatment caused decrease hatching rate and body length significant increase malformation zebrafish. Yolk retention, pericardial edema, swim-bladder deficiency, curved shape were also observed after psoralen treatment. retention might have by...
Diglucose modified berberine derivatives can dramatically promote the uptake of 2-NBDG in both zebrafish larvae and their eyes.
Ischemic diseases have a huge impact on people's health, which can cause blood supply blockage or restriction in specific tissues. Researchers must develop novel drugs with great efficacy and low toxicity for the prevention treatment of such diseases. Isopropyl caffeic acid (KYZ) was one metabolites vivo. This study is to explore protective effect mechanism KYZ ischemic disease from perspective angiogenesis vivo vitro, providing support discovery new candidate drug.The network pharmacology...
The aim of the study is to explore protective effect new gelatin (NG, Xin'ejiao in China) on hematopoietic injury caused by chemotherapy. Zebrafish, at 48 hours post fertilization (hpf), was treated with different chemotherapeutic drugs establish zebrafish damage model reduced thrombocytes and erythrocytes. protecting effects NG erythrocytes were observed, respectively, models. Then, RT-PCR method used detect change mRNA level hematopoiesis-related cytokines scl1, c-myb, pu.1, GATA1, runx1...