To build radiomic prediction models using contrast-enhanced computed tomography (CE-CT) to preoperatively predict malignant potential and mitotic count of gastrointestinal stromal tumors (GISTs).A total 333 GISTs patients were retrospectively included in our study. Radiomic features extracted from the preoperative CE-CT images. According postoperative pathology, categorized by count, respectively. The most valuable chosen a logistic regression model random forest classifier count....

Individuals with subjective memory complaints (SMC) feature a higher risk of cognitive decline and clinical progression Alzheimer's disease (AD). However, the pathological mechanism underlying SMC remains unclear. We aimed to assess intrinsic connectivity network its relationship AD-related pathologies in individuals.We included 44 individuals 40 normal controls who underwent both resting-state functional MRI positron emission tomography (PET). Based on graph theory approaches, we detected...

Mounting evidence has revealed an inverse association between cigarette smoking and the risk of Parkinson's disease (PD). Meanwhile, been found to be associated with cognitive impairment in PD patients. However, neural mechanisms are not fully understood.The aim this study is explore PD.A total 129 patients 69 controls were recruited from Progression Markers Initiative (PPMI) cohort, including 39 regular history (PD-S), 90 without (PD-NS), 26 healthy (HC-S), 43 (HC-NS). Striatal dopamine...

Neuroimaging studies have revealed aberrant network functional connectivity in postherpetic neuralgia (PHN) patients. However, there is a lack of knowledge regarding the relationship between brain during acute period and disease prognosis. The purpose this study was to detect characteristic process herpes zoster (HZ) pain chronification identify whether abnormal can predict outcome patients with HZ. In cross-sectional study, 31 PHN, 33 recuperation from (RHZ), 28 (AHZ) were recruited...

Postherpetic neuralgia (PHN) is a debilitating condition resulting from herpes zoster infection, characterized by persistent pain that significantly impacts quality of life. This study aimed to investigate the white matter microstructural alterations associated with PHN and assess relationship between diffusion metrics clinical symptoms. A total 29 patients PHN, 28 recovering (RHZ), 27 healthy controls (HC) were recruited, assessments obtained evaluate intensity psychological distress....

Abstract Depression often occurs concurrently with postherpetic neuralgia, yet the neural mechanism underlying pain-depression comorbidity remains poorly understood. For this observational study, we recruited 17 depressed neuralgia patients, 19 non-depressed and 34 healthy controls for resting-state functional MRI scans. We firstly investigated differences of fractional amplitude low-frequency fluctuation regional homogeneity values among three groups to identify a characteristic brain...

The present study aimed to investigate the value of magnetic resonance imaging (MRI) in diagnosis giant cell tumor tendon sheath (GCTTS), including localized (L‑) and diffuse (D‑) types. A total 38 patients with GCTTS, 31 L‑GCTTS 7 D‑GCTTS, diagnosed by surgery pathology, were retrospectively analyzed. All underwent MRI examination. Of L‑GCTTS, tumors located hand wrist (18 patients), ankle foot (10 cases), knee joint (2 cases) temporomandibular (1 case). lesions either relation a or...

Abstract Study Objectives We examined electroencephalogram (EEG) spectral power to study abnormalities in regional brain activity post-traumatic stress disorder (PTSD) during sleep. aimed identify sleep EEG markers of PTSD that were reproducible across nights and subsamples our population. Methods Seventy-eight combat-exposed veteran men with (n = 31) without 47) completed two consecutive high-density recordings a laboratory. performed spectral-topographical analyses on data from both...

Alzheimer's disease (AD) has a long neuropathological accumulation phase before the onset of dementia. Such AD deposition between neurons impairs synaptic communication, resulting in networks disorganization. Our study aimed to explore evolution patterns gray matter structural covariance (SCNs) along continuum. Based on AT(N) (i.e., Amyloid/Tau/Neurodegeneration) pathological classification system, we classified subjects into four groups using cerebrospinal fluid amyloid-beta1–42 (A) and...

Background: The biological diagnosis criteria of the Alzheimer's disease (AD) suggests that previous work may misclassify cognitive impairment caused by other factors into AD. Consequently, re-assessing imaging profile AD continuum is needed. Considering high vulnerability cortical association fibers, we aimed to elucidate demyelination process in biologically defined. Methods: According criteria, determined positive amyloid status (A+) as cerebrospinal fluid (CSF) amyloid1-421.11. Also, Tau...

ABSTRACT Background: Patients with the postural instability and gait difficulty (PIGD) subtype of Parkinson disease (PD) are at a higher risk dysfunction less responsive to dopamine replacement therapy. The PIGD was found largely associate white matter lesions, but details diffusion changes within these lesions have not been fully investigated. Voxel-based analysis for tensor imaging data is one preferred measures compare in each voxel any part brain. Methods: PD patients (n=12) non-PIGD...

Nicotine dependence (ND) is a chronic, relapsing mental disorder characterized by compulsive cigarette seeking and smoking. Although the cerebellum plays an increasingly implicated role in ND, exact cerebellar alterations ND remain unclear. Identifying localization of these abnormalities may help to further understand ND. Thus, we investigated structural functional large sample smokers using spatially unbiased infratentorial template (SUIT). High-resolution magnetic resonance imaging (MRI)...

Background: Recently, National Institute on Aging-Alzheimer's Association (NIA-AA) has proposed a biological definition of Alzheimer's disease (AD): individuals with both abnormal amyloid and tau biomarkers (A+T+) would be defined as AD. It remains unclear why different cognitive status are present in subjects Resting-state functional magnetic resonance imaging (rsfMRI) provided an opportunity to reveal the brain activity patterns biologically-defined AD cohort. We aimed investigate distinct...

Working memory capacity (WMC) measures the amount of information that can be maintained online in face distraction. Past work has shown efficiency with which frontostriatal circuit filters out task-irrelevant distracting is positively correlated WMC. Recent demonstrated a role posterior alpha oscillations (8-13 Hz) providing sensory gating mechanism. We investigated relationship between load modulation power and WMC two verbal working experiments. In both experiments, we found increased...

Though sleep disturbance constitutes the risk factor for Alzheimer's disease (AD), underlying mechanism is still unclear. This study aims to explore interaction between disturbances and AD on brain function. We included 192 normal controls, 111 mild cognitive impairment (MCI), 30 patients, with either poor or (PS, NS, respectively). To strength stability of activity, we used static amplitude low-frequency fluctuation (sALFF) dynamic ALFF (dALFF) variance. Further, examined white matter...

Abstract The low-temperature nonequilibrium characteristics of dielectric barrier discharge (DBD) make it an important candidate for the decomposition and conversion CO 2 . In this study, quartz, alumina zirconia are selected as dielectrics to investigate effect materials planar DBD reactor on It is shown that under same input power conditions, has highest rate when used a dielectric, followed by alumina, quartz lowest. Combined with analysis measured electrical characteristics, transferred...

Immune checkpoint inhibitors (ICIs) have been widely used in the treatment of cancer. Moreover, immune-related adverse events (irAEs) become a new clinical challenge. ICI-associated myocarditis is rare but fatal condition among diverse organ injuries, and early recognition effective interventions are critical for patients.In this report, we present case healthy 60-year-old male who was diagnosed with lung squamous cell carcinomas following chemotherapy received ICIs. The patient presented...

Abstract Background Coffee is the most widely consumed psychostimulant worldwide. Emerging evidence indicates that coffee consumption habit significantly reduces risk of developing Parkinson’s disease (PD). However, effect on nigrostriatal dopaminergic neurodegeneration still largely unknown. We therefore aim to investigate role in using dopamine transporter (DAT) imaging PD and healthy controls (HC). Methods A total 138 patients 75 HC with questionnaires about consumption, DAT scans were...