- Acoustic Wave Phenomena Research
- Structural Health Monitoring Techniques
- Vehicle Noise and Vibration Control
- Ultrasonics and Acoustic Wave Propagation
- Aerodynamics and Acoustics in Jet Flows
- Cellular and Composite Structures
- Wind and Air Flow Studies
- Neuropeptides and Animal Physiology
- Building Energy and Comfort Optimization
- Vibration and Dynamic Analysis
- Receptor Mechanisms and Signaling
- Noise Effects and Management
- Nanofluid Flow and Heat Transfer
- Fluid Dynamics and Turbulent Flows
- Non-Destructive Testing Techniques
- Vibration Control and Rheological Fluids
- Infection Control and Ventilation
- Composite Structure Analysis and Optimization
- Natural Fiber Reinforced Composites
- Pharmacological Receptor Mechanisms and Effects
- Optical measurement and interference techniques
- Structural Engineering and Vibration Analysis
- Phenothiazines and Benzothiazines Synthesis and Activities
- Mechanical Behavior of Composites
- Fluid Dynamics and Vibration Analysis
University of Naples Federico II
2016-2025
Federico II University Hospital
2024
Ingegneria dei Trasporti (Italy)
2014-2023
CTO Hospital
2021
KU Leuven
2021
Politecnico di Milano
1985-2018
University of Catania
2007-2017
University of Florence
1996-2017
Ospedale Monaldi
2014-2016
University of Campania "Luigi Vanvitelli"
2014-2016
(-)-cis-1-Methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol (SB-612111) is a novel human opiate receptor-like orphan receptor (ORL-1) antagonist that has high affinity for the clonal ORL-1 (hORL-1 K(i) = 0.33 nM), selectivity versus mu-(174-fold), delta-(6391-fold), and kappa (486-fold)-opioid receptors able to inhibit nociceptin signaling via hORL-1 in whole cell gene reporter assay. SB-612111 no measurable antinociceptive effects vivo mouse...
To reduce their space requirement, quarter wavelength resonators are coiled up into a spiral to have the shape of flat cylinder. The practical implementation these is tested using 3D printing, laser cutting and machining. Numerical simulations impedance tube measurements first compared for normally incident plane wave excitation. This step allows evaluate effect resonator's inlet diameter, internal wall thickness, overall height as well its constitutive material. A series samples then...
Bicuspid aortic valve (BAV)-related aortopathy is increasingly recognized to be a heterogeneous disease entity, although the surgical approach, from indications techniques, still standard rather than individualized. We aimed define determinants of dilatation in BAV patients stratified according morphotype. A consecutive echocardiographic series 622 was analysed. Among demographic (age, sex), anthropometric (height, weight, body surface area, mass index), clinical (associated diseases) and...
In this paper a vibration-based approach to identify crack in wind turbine blade is described and demonstrated numerically experimentally. Operational modal analysis has been performed before after buckling test, vibration data, gathered from some accelerometers placed along the blade, was used monitor integrity of structure, since parameters are directly influenced by physical properties structures. Additionally numerical prediction done both with full-scale model one-dimensional model. The...
Comfort plays an increasingly important role in the interior design of airplanes. In general, comfort is defined as 'freedom from pain, well-being'; scientific literature, indeed, it a pleasant state physiological, psychological and physical harmony between human being environment or sense subjective well-being. Cabin noise passenger aircraft one parameter, which creates straightaway discomfort when exceeding personal thresholds. general cabin varies by seat position changes with flight...
Guided wave-based methods for damage detection have been widely investigated as techniques to identify damages and their dimensions in structures. Most of the research activities presented literature performed focusing on simple case studies a laboratory environment, whereas Structural Health Monitoring systems should be under operational loading conditions. When subjected an load, propagation mechanisms can change, suffering from interaction between propagating signal scattered waves due...
The acoustic modeling of materials is paramount importance for the accurate prediction untested configurations and development optimal manufacturing strategies. Nevertheless, this task presents significant challenges due to complexity parameters governing materials, such as porous media, each which demands distinct experimental setups procedures, often difficult implement. Inverse methods parameter estimation rely on physical approximations require protocols that are highly sensitive...
The specific involvement of the delta-opioid receptor in control nociception was explored by investigating pharmacological activity vivo a selective, orally active, and centrally penetrant agonist. [8R-(4bS*,8aalpha,8abeta,12bbeta)]7,10-dimethyl-1-methoxy-11-(2-methylpropyl)oxycarbonyl 5,6,7,8,12,12b-hexahydro-(9H)-4,8-methanobenzofuro[3,2-e]pyrrolo[2,3-g]isoquinoline hydrochloride (SB-235863) is new pyrrolomorphinan with high affinity (Ki = 4.81 +/- 0.39 nM) for receptor, full agonist...
The main scope of this work is to study the effect embedding a periodic pattern inside porous material, in order passively improving its acoustic performance terms sound transmission loss. A contemplated application improvement classical aeronautical soundproofing packages. In reach goal, numerical models an package including patterns are implemented using finite element method and Transfer Matrix Method. Firstly, some proposed configurations experimentally tested, providing comparison...
Abstract In the past decades, exponential rise in fossil fuel consumption has led to a pressing need for sustainable energy solutions. This surge use not only caused severe environmental repercussions but also raised questions about our global dependence on such non-renewable resources. Addressing these detrimental effects, NASA urged aeronautic industry reduce aircraft burn by substantial 70% before 2025. As result of comprehensive government and studies, electric propulsion emerged as...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT(1S)-1-(Aminomethyl)-2-(arylacetyl)-1,2,3,4-tetrahydroisoquinoline and heterocycle-condensed tetrahydropyridine derivatives: members of a novel class very potent .kappa. opioid analgesicsVittorio Vecchietti, Geoffrey D. Clarke, Roberto Colle, Giuseppe Giardina, Petrone, Massimo SbacchiCite this: J. Med. Chem. 1991, 34, 8, 2624–2633Publication Date (Print):August 1, 1991Publication History Published online1 May 2002Published inissue 1 August...
Similarity theory is a branch of engineering science that deals with establishing conditions similarity among phenomena and applied to various fields, such as structural problems, vibration impact. Tests numerical simulation scaled models are still valuable design tool, whose purpose accurately predict the behaviour large or small prototypes through scaling laws experimental results. The aim this paper complete incomplete stiffened cylinders by applying distorted in similitude. investigation...