A5072959014- Cellular Mechanics and Interactions
- Multisensory perception and integration
- Neural dynamics and brain function
- Force Microscopy Techniques and Applications
- Nuclear Structure and Function
- Tendon Structure and Treatment
- Advanced Fluorescence Microscopy Techniques
- Surgical Sutures and Adhesives
- Neuroscience and Music Perception
- Microtubule and mitosis dynamics
- Olfactory and Sensory Function Studies
- Imbalanced Data Classification Techniques
- Skin and Cellular Biology Research
- Pharmacology and Obesity Treatment
- Orthopaedic implants and arthroplasty
- Cardiomyopathy and Myosin Studies
- Hydraulic and Pneumatic Systems
- Sarcoma Diagnosis and Treatment
- Rough Sets and Fuzzy Logic
- Hydraulic flow and structures
- Adipose Tissue and Metabolism
- Muscle Physiology and Disorders
- Elasticity and Material Modeling
- Financial Distress and Bankruptcy Prediction
- Water Systems and Optimization
Indian Institute of Technology Bombay
2019-2024
National Brain Research Centre
2016-2024
IITB-Monash Research Academy
2019-2024
Institute of Engineering
2021
Monash University
2020
Technion – Israel Institute of Technology
2019
Observable lip movements of the speaker influence perception auditory speech. A classical example this is reported by listeners who perceive an illusory (cross-modal) speech sound (McGurk-effect) when presented with incongruent audio-visual (AV) stimuli. Recent neuroimaging studies AV accentuate role frontal, parietal and integrative brain sites in vicinity superior temporal sulcus (STS) for multisensory perception. However, if how does network across whole participates during processing...
The mechanisms by which the mechanoresponsive actin crosslinking protein α-actinin-4 (ACTN4) regulates cell motility and invasiveness remain incompletely understood. Here, we show that, in addition to regulating protrusion dynamics focal adhesion formation, ACTN4 transcriptionally expression of non-muscle myosin IIB (NMM IIB; heavy chain encoded MYH10), is essential for mediating nuclear translocation during 3D invasion. We further that an indirect association between NMM IIA (heavy MYH9)...
Large nuclear deformations during migration through confined spaces have been associated with membrane rupture and DNA damage. However, the stresses damage remain unclear. Here, using a quasi-static plane strain finite element model, we map evolution of shape cell deformable matrix. Plastic deformation nucleus observed for stiff transiting stiffer matrix lowered stresses, but also led to kinking membrane. In line model predictions, transwell experiments fibrosarcoma cells showed that while...
Abstract Multisensory processing involves participation of individual sensory streams, e.g., vision, audition to facilitate perception environmental stimuli. An experimental realization the underlying complexity is captured by “McGurk-effect”- incongruent auditory and visual vocalization stimuli eliciting illusory speech sounds. Further studies have established that time-delay between onset signals (AV lag) perturbations in unisensory streams are key variables modulate perception. However,...
Abstract Speech perception requires the binding of spatiotemporally disjoint auditory–visual cues. The corresponding brain network-level information processing can be characterized by two complementary mechanisms: functional segregation which refers to localization in either isolated or distributed modules across brain, and integration pertains cooperation among relevant modules. Here, we demonstrate using magnetic resonance imaging recordings that subjective perceptual experience...
Abstract Cells’ ability to apply contractile forces their environment and sense its mechanical properties (e.g. rigidity) are among most fundamental features. Yet, the interrelations between contractility mechanosensing, in particular whether force generation depends on not understood. We use theory extensive experiments study time evolution of cellular show that they generated by time-dependent actomyosin displacements independent environment’s rigidity. Consequently, non-mechanosensitive....
Abstract Large nuclear deformations during migration through confined spaces have been associated with membrane rupture and DNA damage. However, the stresses damage remain unclear. Here, using a quasi-static plane strain finite element model, we map evolution of shape cell deformable matrix. Plastic deformation nucleus observed for stiff transiting stiffer matrix lowered stresses, but also led to kinking membrane. In line model predictions, transwell experiments fibrosarcoma cells showed...
This paper will discuss about the different approaches to fraud detection such as Data mining, machine learning and artificial intelligence statistical data analysis. Then we list some of technical troublesome challenges modern techniques. A comparison study these techniques is also done according metrics like precision, False Alarm Rate (FAR), Accuracy, Cost, True Positive (TPR) against categories frauds internal bank fraud, credit card loan fraud. Finally, disadvantages existing systems...
Speech perception requires the binding of spatiotemporally disjoint auditory--visual cues. The corresponding brain network-level information processing can be characterized by two complementary mechanisms: functional segregation which refers to localization in either isolated or distributed modules across brain, and integration pertains cooperation among relevant modules. Here, we demonstrate using fMRI recordings that subjective perceptual experience multisensory speech stimuli, real...
The first quantitative calculation of the hydraulic jump was carried out only a few years ago by Bohr et al. Since it is jump, we have analysed from slightly different point view.Our results are similar to those et.al.
Abstract The mechanisms by which the mechanoresponsive actin crosslinking protein α -actinin-4 (ACTN4) regulates cell motility and invasiveness remains incompletely understood. Here we show that in addition to regulating protrusion dynamics focal adhesion formation, ACTN4 transcriptionally expression of non-muscle myosin IIB (NMM IIB), is essential for mediating nuclear translocation during 3D invasion. We further demonstrate association between NMM IIA at front ensures retention periphery....
Abstract A physician palpates a tissue to detect an embedded tumor nodule by sensing increase in local stiffness and size. The Hertz contact model, however, is unable predict the material or physical properties of healthy finite thickness. In this study, utilizing hyperelastic we propose general methodology analyze extent which stiffness, size, depth affect its detectability. Using dimensional analysis, generate simple power-law relations nodules during indentation. Our results indicate that...