A5017068284- Functional Brain Connectivity Studies
- Radiomics and Machine Learning in Medical Imaging
- Treatment of Major Depression
- Advanced Nanomaterials in Catalysis
- Nanoplatforms for cancer theranostics
- Ultrasound in Clinical Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Heart Rate Variability and Autonomic Control
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Neurotransmitter Receptor Influence on Behavior
- Gastric Cancer Management and Outcomes
- Tryptophan and brain disorders
- Olfactory and Sensory Function Studies
- EEG and Brain-Computer Interfaces
- Esophageal and GI Pathology
- COVID-19 Clinical Research Studies
- IgG4-Related and Inflammatory Diseases
- Mental Health Research Topics
- Venous Thromboembolism Diagnosis and Management
- Soft tissue tumor case studies
- Medical Imaging Techniques and Applications
- Congenital Diaphragmatic Hernia Studies
- Pancreatic and Hepatic Oncology Research
- Memory and Neural Mechanisms
Hunan Provincial People's Hospital
2016-2025
Hunan Normal University
2020-2025
Anhui University of Traditional Chinese Medicine
2021-2024
Soochow University
2024
First Affiliated Hospital of Soochow University
2024
Abstract To overcome current limitations in photoimmunotherapy, such as insufficient tumor antigen generation and a subdued immune response, novel photo‐/metallo dual‐mode immunotherapeutic agent (PMIA) is introduced for potent near‐infrared (NIR) light‐triggered cancer therapy. PMIA features dumbbell‐like AuPt heterostructure decorated with starry Pt nanoclusters, meticulously engineered enhancing plasmonic catalysis through multi‐dimensional regulation of growth on Au nanorods. Under NIR...
COVID-19 has led to reports of fatigue and sleep problems. Brain function changes underlying problems (SP) post-COVID-19 are unclear. This study investigated SP-related brain functional connectivity (FC) alterations. Fifty-five survivors with SP (COVID_SP) 33 without (COVID_NSP), matched for demographics, completed PSQI underwent rs-fMRI at baseline 2-month follow-up. Correlations between FC clinical data were analyzed by Pearson correlation analysis Gaussian random field (GRF) correction....
Disintegration in thalamocortical integration suggests its role the mechanistic 'switch' from recreational to dysregulated drug seeking/addiction. In this study, we aimed address whether thalamic nuclear groups show altered functional connectivity within cerebral cortex chronic ketamine users. One hundred and thirty subjects (41 users 89 control subjects) underwent rsfMRI (resting-state Magnetic Resonance Imaging). Based on partial correlation analysis partitioned thalamus into six that...
PURPOSE: This retrospective study is designed to develop a Radiomics-based strategy for preoperatively predicting lymph node (LN) status in the resectable pancreatic ductal adenocarcinoma (PDAC) patients. METHODS: Eighty-five patients with histopathological confirmed PDAC are included, of which 35 LN metastasis positive and 50 negative. Initially, 1,124 radiomics features computed from CT images each patient. After series feature selection, Radiomics logistic regression (LOG) model...
Background:The medial prefrontal cortex (mPFC) contains various neurotransmitter systems and plays an important role in drug use. Broad body of literature on how methamphetamine (MA) affects the structure metabolism animal's mPFC is emerging, while effects metabolites among human still unclear. In this study, proton magnetic resonance spectroscopy (¹H MRS) was used to measure dependent subjects. Methods:Sixty-one subjects with a history MA dependence (fulfiled Diagnostic Statistical Manual...
To retrospectively analyze and stratify the initial clinical features chest CT imaging findings of patients with COVID-19 by gender age.Data 50 were collected in two hospitals. The manifestations, laboratory examination analyzed, a stratification analysis was performed according to age [younger group: <50 years old, elderly group ≥50 old].Most had history epidemic exposure within 2 weeks (96%). main complaints are fever (54%) cough (46%). In images, ground-glass opacity (GGO) is most common...
To establish and validate an MRI T2∗WI-based radiomics nomogram model to discriminate hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma (ICCA).174 patients were retrospectively collected, who diagnosed with primary hepatic by surgery or puncture pathology received preoperative scans including T2∗WI scans. There 113 cases of HCC 61 mass-type ICCA. was used for feature extraction, the extent lesions manually outlined at largest layer T2∗WI, dimension reduction performed mRMR...
Background: Craving is the predictor of relapse, and insula cortex (IC) a critical neural substrate for craving drug seeking. This study investigated whether IC abnormalities among MA users can detect state predict relapse susceptibility. Methods: A total 142 subjects with history dependence completed structural MRI (sMRI) scans, 30 (10 relapsed) 4-month follow-up scans. was measured by Visual Analog Scale Craving. Abnormalities gray matter volume (GMV) between without were voxel-based...
Abstract Congenital anatomical abnormalities of the pediatric bronchus is a rare and easily overlooked condition. In this study, we identified an 8‐year‐old patient with congenital anomalies bronchial origin that caused his clinical manifestations cough shortness breath. This diagnosis needs to be taken into possible consideration when similar occur in without cause.
Background Insular subdivisions show distinct patterns of resting state functional connectivity with specific brain regions, each different significance in chronic cigarette smokers. This study aimed to explore the altered dynamic (dFC) insular Methods Resting-state BOLD data 31 smokers nicotine dependence and 27 age-matched non-smokers were collected. Three bilateral regions interest (dorsal, ventral, posterior) set as seeds for analyses. Sliding windows method was used acquire dFC metrics...
A 54-year-old woman was admitted to the hospital due unexplained weight loss Physical examination revealed a significant abdominal mass. CT scanning large mixed-density mass in abdomen closely associated with liver.
Abstract This study aims to optimise the protocol for low-dose pulmonary computed tomography (CT) scanning of infants by studying effects selective photon shield (SPS) technique third-generation dual-source CT (DSCT) on image quality and radiation dose a chest in white rabbits under different tube currents. Twelve similar weight an infant were selected randomly divided into experimental group control group. The groups (A1–A5) scanned at low DSCT using SPS current × time (60, 50, 40, 30, 20...
Objective This study aimed to investigate changes of computed tomography pulmonary angiography (CTPA)–derived parameters in older adults with acute embolism (APE). Methods According the artery obstruction index (PAOI), patients APE were divided into A1 (PAOI ≥30%, n = 57) and A2 <30%, 40) groups. Participants without placed group B (n 170). The left atrial (LA) ventricular (LV) among three groups compared, parameter 44 analyzed before after treatment. correlation between severity was...
Abstract Background A version of ketamine, called Esketamine has been approved for treatment-resistant depression (TRD). Ketamine (“K powder”), a “dissociative” anesthetic agent, however, used non-medically alone or with other illicit substances. Our previous studies showed link between non-medical ketamine use and brain structural functional alterations. We found dorsal prefrontal gray matter reduction in chronic users. It is unknown, whether these observations might parallel findings...