A5100346907- Venous Thromboembolism Diagnosis and Management
- Lung Cancer Treatments and Mutations
- Cerebrovascular and Carotid Artery Diseases
- Gastric Cancer Management and Outcomes
- Aortic aneurysm repair treatments
- Diagnosis and Treatment of Venous Diseases
- Vascular Procedures and Complications
- Acute Ischemic Stroke Management
- Ferroptosis and cancer prognosis
- Aortic Disease and Treatment Approaches
- Peripheral Artery Disease Management
- Cardiac, Anesthesia and Surgical Outcomes
- Gallbladder and Bile Duct Disorders
- Lung Cancer Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Colorectal Cancer Treatments and Studies
- Intensive Care Unit Cognitive Disorders
- Infectious Aortic and Vascular Conditions
- Central Venous Catheters and Hemodialysis
- Cancer Genomics and Diagnostics
- Biliary and Gastrointestinal Fistulas
- Radiomics and Machine Learning in Medical Imaging
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer-related molecular mechanisms research
- Cancer, Lipids, and Metabolism
Inner Mongolia Medical University
2023-2025
Nanchang University
2024-2025
Affiliated Hospital of Qingdao University
2019-2025
Harbin Medical University
2025
Qingdao University
2019-2025
First Affiliated Hospital of Hebei Medical University
2018-2024
Hebei Medical University
2018-2024
Shunyi Hospital of Beijing Traditional Chinese Medicine Hospital
2024
Sichuan University
2024
West China Hospital of Sichuan University
2024
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible disease characterized by excessive fibroblast to myofibroblast differentiation with limited therapeutic options. Curdione, sesquiterpene compound extracted from the essential oil of Curcuma aromatica Salisb, has anti-inflammatory anti-tumor effects. However, role curdione in IPF still unclear. Methods The effects were evaluated bleomycin (BLM)-induced mouse model. C57BL/6 mice treated BLM on day 0...
Abdominal aortic aneurysm (AAA) is a common disease, which characterized by the apoptosis of vascular smooth muscle cells (VSMCs). In previous years, microRNAs (miRNAs) have been associated with AAA and functionally implicated in pathogenesis this disease. However, role miRNAs VSMCs remains to be fully elucidated. The present study aimed elucidate mechanism protecting against hydrogen peroxide (H2O2)‑induced VSMCs. expression peripheral blood from patients diagnosed was analyzed using...
Background. Gastric cancer (GC), an extremely aggressive tumor with a very different prognosis, is the third leading cause of cancer-related mortality. We aimed to construct ferroptosis-related prognostic model that can be distinguished prognostically. Methods. The gene expression and clinical data GC patients were downloaded from Cancer Genome Atlas (TCGA) Gene Expression Omnibus database (GEO). genes obtained FerrDb. Using “limma” R package univariate Cox analysis, differential value...
Background & Aims: Gastric cancer is the common malignancies from worldwide. Endoscopy currently most effective method to detect early gastric (EGC). However, endoscopy not infallible and EGC can be missed during endoscopy. Artificial intelligence (AI)-assisted endoscopic diagnosis a recent hot spot of research. We aimed quantify diagnostic value AI-assisted in diagnosing EGC. Method: The PubMed, MEDLINE, Embase Cochrane Library Databases were searched for articles on application...
Intracerebral haemorrhage (ICH) can be a catastrophic event; even if the initial stages of pathology were well-managed, number patients experience varied residual neurological deficits following insult. Ferroptosis is recently identified type cell demise which tightly linked to impairment associated with ICH. In current work, prophylactic impact scalp acupuncture (SA) therapy on autologous blood injection murine models ICH was investigated in order establish whether SA could mitigate...
Crocin (CRO) is feasible in alleviating atherosclerosis (AS), the mechanism of which was therefore explored study. High-fat diet (HFD)-induced apolipoprotein E-deficient (ApoE-/-) mice and lysophosphatidic acid (LPA)-treated macrophages received CRO treatment. Treated macrophage viability determined via MTT assay. In both murine macrophage, lipid level total Cholesterol/Cholesteryl l Ester (TC/CE) levels were quantified by oil-red-O staining ELISA, respectively. Lipid droplet, aortic plaque...
We investigated the incidence and clinical features of venous thromboembolism (VTE) in inpatients with mental illnesses.We retrospectively analyzed records illnesses confirmed VTE at The First Hospital Hebei Medical University between August 2018 July 2022. recorded demographic characteristics, psychosis-related conditions, thrombus distribution.Among 12939 patients diagnosed illness, 156 (1.21%) presented first visit or during disease course. Crude varied significantly across illnesses,...
Proton pump inhibitors (PPIs) are currently routinely used for the treatment of reflux esophagitis (RE); however, with frequent symptom recurrence after discontinuation and limited clinical improvement in accompanying gastrointestinal symptoms. This study aims to explore adjuvant therapeutic effect Bifidobacterium supplement RE patients. A total 110 eligible patients were recruited randomly assigned placebo probiotic groups. All treated rabeprazole tablets simultaneously received either...
Background: Lung adenocarcinoma (LUAD) possesses a poor prognosis with low 5-year survival rate even for stages I-III resected patients, it is thus critical to understand the determinants that affect and discover new potentially prognostic biomarkers. Somatic copy number alterations (CNAs) are major source of genomic variations driving tumor evolution, CNAs screening may identify Methods: Oncoscan MIP array was used analyze patterns on formalin fixed paraffin embedded(FFPE) specimens from...
(1) Background: Afatinib has been approved for patients with non-small cell lung cancer (NSCLC) carrying major uncommon epidermal growth factor receptor gene (EGFR) mutations. Dacomitinib, another second-generation tyrosine kinase inhibitor, also shown promising potential EGFR However, no comparative study conducted. (2) Methods: Two cohorts were employed: the AFANDA cohort, an ambispective cohort including 121 mutations admitted to two tertiary hospitals in China, and external validation...
The aim of this study was to build an artificial neural network (ANN) model for predicting surgery-related pressure injury (SRPI) in cardiovascular surgical patients.Prospective cohort study.One hundred forty-nine patients who had surgery were included the study. This conducted a 1000-bed teaching hospital Eastern China where 250 350 cardiac surgeries are performed each year.We prospective among consecutive undergoing between January and December 2015. ANN built based on possible SRPI risk...
Objectives: To compare the long-term outcomes of endovascular repair (EVAR) versus open for abdominal aortic aneurysm (AAA).Design: We retrospectively reviewed consecutive AAA patients treated with EVAR (n = 89) or 136) from January 1998 to December 2008. Results: More in group had a longer duration hospital stay. The operation time was significantly surgery than (p <0.001), and percentage requiring transfusion higher EVAR. Patients incidence cardiac insufficiency after did those group....
To evaluate the clinical outcomes of early stenting (≤14 days) or late (>14 in patients who underwent intracranial stent placement.Patients with ischemic stroke caused by 70-99% atherosclerotic stenosis combined poor collaterals were enrolled. The group, within 14 days last symptoms, compared group >14 from symptom. treated either a balloon-mounted self-expanding as determined operators following guideline. baseline characteristics and evaluated compared.One hundred fifteen recruited into...
Aim: To evaluate intravenously injected bovine serum albumin-templated gold nanoparticles (BSA-GNPs) for radiosensitization effects on H22 hepatoma-bearing mice. Materials & methods: BSA-GNPs in different size were with a dose of 4 mg Au/kg. After 30 min injection, the tumor-bearing mice irradiated 5 Gy x-ray. Results: 8, 50 and 187 nm synthesized have no obvious cytotoxicity to HeLa, HepG2 HeCat cells when concentration was up 32 μM. And physiological injury occurred intravenous injection...
The objectives are to evaluate the application of computed tomography venography (CTV) in diagnosis iliac vein compression syndrome (IVCS), and assess factors related incidence development IVCS recurrence varicose veins. Imaging data 120 patients with chronic venous disease (CVD) lower extremity 68 subjects without CVD (control) were retrospectively reviewed by radiologists blinded groups. CTV, conventional venography, Doppler ultrasound compared contributing for also analyzed. CTV required...