Yan Sun

ORCID: 0000-0003-0706-1204
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About
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Research Areas
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Lung Cancer Research Studies
  • Lymphoma Diagnosis and Treatment
  • Head and Neck Cancer Studies
  • Glaucoma and retinal disorders
  • Viral-associated cancers and disorders
  • Parathyroid Disorders and Treatments
  • Esophageal Cancer Research and Treatment
  • CAR-T cell therapy research
  • Corneal surgery and disorders
  • Inflammatory Biomarkers in Disease Prognosis
  • Sarcoma Diagnosis and Treatment
  • Esophageal and GI Pathology
  • Fibroblast Growth Factor Research
  • Colorectal Cancer Treatments and Studies
  • Biochemical effects in animals
  • Intraocular Surgery and Lenses
  • Genetic Syndromes and Imprinting
  • Retinal and Macular Surgery
  • Cancer-related molecular mechanisms research
  • Anesthesia and Neurotoxicity Research
  • RNA modifications and cancer
  • Retinal Diseases and Treatments

Second Affiliated Hospital of Zhejiang University
2025

Qingdao University
2025

Qingdao Municipal Hospital
2025

Peking University
2009-2024

Peking University Cancer Hospital
2009-2024

Linyi City Chinese Medicine Hospital
2011-2024

Academy of Medical Sciences
1997-2023

Shandong Tumor Hospital
2023

Shandong First Medical University
2023

Shijiazhuang Tiedao University
2023

Patients with systolic heart failure and anemia have worse symptoms, functional capacity, outcomes than those without anemia. We evaluated the effects of darbepoetin alfa on clinical in patients

10.1056/nejmoa1214865 article EN New England Journal of Medicine 2013-03-10

To explore the clinicobiologic features and outcomes of diffuse large B-cell lymphoma (DLBCL) patients in China according to primary site.A total 1,085 diagnosed with DLBCL National Cancer Center/Cancer Hospital, Chinese Academy Medical Sciences Peking Union College during a 6-year period were enrolled. Their clinical characteristics analyzed site.In patients, 679 (62.6%) cases nodal (N-DLBCL) 406 (37.4%) extranodal (EN-DLBCL). The most common sites N-DLBCL lymphonodus (64.8%), Waldeyer's...

10.21147/j.issn.1000-9604.2019.01.10 article EN Chinese Journal of Cancer Research 2019-01-01

CRA8003 The full, final text of this abstract will be available in Part II the 2009 ASCO Annual Meeting Proceedings, distributed onsite at on May 30, 2009, and as a supplement to June 20, issue Journal Clinical Oncology. [Table: see text]

10.1200/jco.2009.27.15_suppl.cra8003 article EN Journal of Clinical Oncology 2009-05-20

<title>Abstract</title> Acute lung injury (ALI) is a common serious complication following deep hypothermic circulatory arrest (DHCA). Monocytes and macrophages play crucial role in producing inflammatory mediators regulating innate adaptive immunity. In our specific rat model of DHCA‐induced ALI, We have previously shown that autophagy actually has detrimental effect on rather than protective effect. Recently, we found monocytes an important function this model. Here, single-cell RNA...

10.21203/rs.3.rs-6147117/v1 preprint EN Research Square (Research Square) 2025-04-16

Abstract Purpose This study aimed to develop a prognostic nomogram in diffuse large B-cell lymphoma (DLBCL) and compare it with traditional systems. Materials methods We included 1,070 consecutive nonselected patients DLBCL the National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences, between 2006 2012. A based on Cox proportional hazards model was developed. Results The entire group were divided into primary (n = 748)...

10.1634/theoncologist.2018-0361 article EN The Oncologist 2019-04-05

Leptin may play a role in mediating obesity-related hypertension. However, its effects on the vasculature and blood pressure (BP) remain poorly defined humans.In first study, we performed short-term, placebo-controlled, randomized, double-blind, cross-over experiment investigating actions of recombinant human leptin (r-metHuLeptin) 15 nonobese adults. To compliment acute retrospectively analyzed available BP results from previously 85-day, parallel weight-loss study using r-metHuLeptin 284...

10.1089/met.2006.0023 article EN Metabolic Syndrome and Related Disorders 2007-04-30

This study evaluated the efficacy and safety of AMG416 (etelcalcitide), a novel peptide agonist calcium (Ca)-sensing receptor given intravenously (IV) after each hemodialysis session for treatment secondary hyperparathyroidism (SHPT).Adult subjects with SHPT on enrolled in 12-week, dose titration (parent) followed by an open-label extension phase. was administered IV, thrice weekly starting at 5 mg/session titrated based subject's parathyroid hormone (PTH) albumin-corrected Ca (cCa) to...

10.1159/000442754 article EN American Journal of Nephrology 2015-01-01

The clear cell renal carcinoma (ccRCC) is not only a malignant disease but also an energy metabolic disease, we aimed to identify novel prognostic model based on glycolysis-related long non-coding RNA (lncRNAs) and explore its mechanisms. With the use of Pearson correlation analysis between differentially expressed genes lncRNAs from Cancer Genome Atlas (TCGA) dataset, identified three successfully constructed their expression. diagnostic efficacy clinically predictive capacity signature...

10.3389/fmed.2021.777507 article EN cc-by Frontiers in Medicine 2022-01-10

To assess the visual outcomes and possible risk factors associated with axis alignment rotational stability after implantation of Toric implantable collamer lens (TICL) for correction high myopic astigmatism.In this prospective, nonrandomized clinical study, 54 consecutive eyes 29 patients astigmatism received TICL implantation. evaluate postoperative deviation from intended axis, a digital anterior segment photograph was taken. The ultrasound biomicroscopy(UBM) used to observe...

10.3980/j.issn.2222-3959.2012.04.10 article EN PubMed 2012-01-01

Recent studies from the Alzheimer's Disease Neuroimaging Initiative show that, in USA, 75% of patients with disease are female. To date, there have rarely been any attempts to analyze data by sex or gender, which limits potential for discovering effects gender on disease. Little evidence is available regarding effect and apolipoprotein E (APOE) ε4 white matter (WM) connection functional perspective due lack appropriate techniques detecting blood-oxygen-level-dependent signals WM.We took...

10.1111/ene.14226 article EN European Journal of Neurology 2020-04-18

Dental management prior to radiotherapy is often time-critical, and there are no studies on whether manipulations such as tooth extraction influence the risk of severe radiation-induced oral mucositis (ROM) during radiotherapy. Therefore, aim this study was describe relationship between dental incidence ROM. A retrospective analysis conducted 144 head neck cancer (HNC) patients who received before at Peking University Cancer Hospital, from January 2016 December 2017. Demographic...

10.1016/j.jds.2024.04.030 article EN cc-by-nc-nd Journal of Dental Sciences 2024-05-06

Objective: An effective animal model was needed for research on the pathophysiology of cardiopulmonary bypass (CPB). Rat models were considered suitable into CPB, recently. The aim article is to establish a simple and safe CPB without blood priming in rats, containing advantages controlling temperature precisely, being similar clinical process laying foundation further study deep hypothermic circulatory arrest (DHCA) model. Materials Methods: Ten Sprague-Dawley divided group (n=7) sham...

10.1177/0267659113495914 article EN Perfusion 2013-07-10

The metastatic renal cell carcinoma (mRCC) patients treated with upfront cytoreductive nephrectomy combined α-interferon yields additional overall survival (OS) benefits. It is unclear whether mRCC vascular endothelial growth factor receptor-tyrosine kinase inhibitor (VEGFR-TKI) will benefit from such either. aim of the study was to identify variables for selection who would VEGFR-TKI.Clinical data on 74 enrolled in 5 clinical trials conducted Cancer Hospital (Institute), Chinese Academy...

10.4103/0366-6999.177001 article EN cc-by-nc-nd Chinese Medical Journal 2016-02-19

Cervical esophageal cancer (CEC) is an uncommon malignancy with poor prognosis, and there no specific model that can be used to accurately predict the survival of patients CEC.The Surveillance, Epidemiology, End Results (SEER) database was searched for non-metastatic CEC from 2004 2015. Overall (OS) disease-specific (DSS) rates were calculated using Kaplan-Meier method. Predictive factors analyzed by Cox's proportional hazards regression, a nomogram created probability R software.We...

10.21037/atm-20-2505 article EN Annals of Translational Medicine 2020-12-01
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