A5101483970- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Treatments and Mutations
- Medical Imaging Techniques and Applications
- Gastric Cancer Management and Outcomes
- Cancer, Hypoxia, and Metabolism
- Lung Cancer Research Studies
- Head and Neck Cancer Studies
- Autophagy in Disease and Therapy
- Medical Imaging and Pathology Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Economic and Financial Impacts of Cancer
- Neuroinflammation and Neurodegeneration Mechanisms
- Inflammatory Biomarkers in Disease Prognosis
- Colorectal and Anal Carcinomas
- Glioma Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Lymphoma Diagnosis and Treatment
- Esophageal and GI Pathology
- Circular RNAs in diseases
- Chronic Lymphocytic Leukemia Research
- HER2/EGFR in Cancer Research
- Cancer survivorship and care
- Sarcoma Diagnosis and Treatment
Shandong Provincial Hospital
2011-2025
Dalian Medical University
2022-2025
Shandong First Medical University
2016-2025
Chengdu Medical College
2024-2025
Kunming Medical University
2025
First Affiliated Hospital of Kunming Medical University
2025
First Hospital of Jilin University
2019-2025
Hunan Cancer Hospital
2024
Central South University
2021-2024
Ningxia Medical University
2022-2024
Abstract Dental implants are the most common therapeutic approach for resolving tooth loss and damage. Despite technical advances in treatment, implant failure rates can be as high 23% with major cause of peri‐implantitis: a multi‐species bacterial infection. With an annual growth rate placements 8.78% per annum, caused by infection is significant oral general health issue. The rise antibiotic resistance bacteria further adds pressure to failure; thus, there need adjunctive therapy improve...
Objective To determine the effectiveness and safety of 5-aminolevulinic acid mediated photodynamic therapy (5-ALA PDT) in HR-HPV infected patients with cervical low-grade squamous intraepithelial lesions (LSIL) to explore possible factors affecting treatment outcomes. Methods This retrospective study included 96 histologically confirmed LSIL high-risk human papillomavirus (HR-HPV) infection. They received 5-ALA PDT once a week for total 3 courses. All were evaluated by cytology tests, HPV...
China witnessed an Omicron COVID-19 outbreak at the end of 2022. During this period, medical crowding and enormous pressure on healthcare systems occurred, which might result in occurrence occupational burnout among workers (HCWs). This study aims to investigate prevalence associated mental conditions, such as depressive symptoms, anxiety, PTSD perceived social support, resilience, mindfulness HCWs Chinese mainland during outbreak, explore potential risk protective factors influencing HCWs....
Background Intestinal ischemia-reperfusion injury (IIRI) is a severe clinical condition associated with high morbidity and mortality. Despite advances in understanding the pathophysiology of IIRI, effective diagnostic therapeutic strategies remain limited. Methods Using transcriptome sequencing mouse model we identified potential biomarkers that were significantly upregulated IIRI group compared to sham group. Based on these findings, developed evaluated strategy using milk-derived exosomes...
To explore the lived experiences of patients with advanced pancreatic cancer enrolled in a patient-reported outcomes (PROs) management programme and to preliminarily understand how PROs influences various aspects patient care overall quality life. A qualitative phenomenological study. national centre Southwest China specialised care, comprehensive programme. 15 participants diagnosed cancer. Five key themes emerged from our interviews, including enhanced communication healthcare providers,...
The Rho-associated protein kinase (ROCK) inhibitor Y-27632 is a potential immunotherapeutic agent for cancer treatment. blocks the growth and migration of oral squamous cell carcinoma (OSCC) CAL-27 cells. However, detailed studies on underlying mechanisms have not yet been reported. We investigated effects proliferation, migration, invasion OSCC cells (CAL-27, SCC-4, SCC-9) using Cell Counting Kit-8 assay, ethynyl-2'-deoxyuridine staining, scratch, transwell assay in vitro. Next, ROCK1/2 was...
<h3>Background</h3> Imatinib mesylate has become one of the main chemotherapeutic agents currently used to treat patients with chronic myeloid leukemia (CML). Although cutaneous reactions this drug have been documented before, is first time that Sweet syndrome reported its use. <h3>Observations</h3> We report a case secondary administration imatinib CML. On 2 separate occasions, 53-year-old African American woman CML developed neutrophilic dermatosis consistent after chemotherapy imatinib....
The purpose of this study was to evaluate hypoxia in esophageal squamous cell carcinoma (SCC) with 18F-fluoroerythronitroimidazole positron emission tomography/computed tomography (18F-FETNIM PET/CT). We determined an imaging threshold for hypoxia, quantified the spatiotemporal variability untreated tumor, and evaluated ability 18F-FETNIM PET predict clinical response following concurrent chemoradiotherapy (CCRT). Twenty-eight consecutive patients inoperable SCC esophagus were consecutively...
The aim of the present study is to evaluate role (11)C-choline positron emission tomography/computed tomography (PET/CT) in detecting tumor recurrence and predicting survival post-treatment patients with high-grade gliomas. A total 16 previously treated histopathologically proven glioma were subjected PET/CT scan analysis. We found that sensitivity specificity 100 70 %, whereas those Gd-MRI 83.3 60 respectively. By Cox regression analysis, T/N ratio correlated obviously overall (OS) (hazard...
The study aims to investigate the role of 18F-alfatide positron emission tomography/computed tomography (PET/CT) in predicting short-term outcome concurrent chemoradiotherapy (CCRT) patients with advanced non-small cell lung cancer (NSCLC).Eighteen NSCLC had undergone PET/CT scans before CCRT and parameters including maximum mean standard uptake values (SUVmax/SUVmean), peak (SUVpeak) tumor volume (TVPET TVCT) were obtained. SUVmax normal tissues (lung, blood pool muscle) measured, their...
Background This study aimed to elucidate clinical significance of anaplastic lymphoma kinase (ALK) rearrangement in selected advanced non-small cell lung cancer (NSCLC), compare the application different ALK detection methods, and especially evaluate a possible association between expression outcomes crizotinib-treated patients. Methods status was assessed by fluorescent situ hybridization (FISH), immunohistochemistry (IHC) quantitative RT-PCR (qRT-PCR) 173 NSCLC Clinicopathologic data,...
To investigate the incidence of radiation esophagitis (RE) and tumor local control using esophagus sparing technique in locally advanced non-small cell lung cancer (LANSCLC) treated by simultaneous integrated boost intensity-modulated therapy (SIB-IMRT) concurrent chemotherapy.Eighty-seven patients with stage IIIA/B NSCLC who received definitive SIB-IMRT chemotherapy had been divided into two groups: 1.with technique; 2.without technique. Chi-square test was performed to compare sex,...
Actin filament-associated protein 1-antisense RNA 1 (AFAP1-AS1) plays an important role in the development and progression of several human cancers. However, its biological function gastric cancer (GC) is still unknown.We used qRT-PCR to detect relative expression AFAP1-AS1 GC tissues cell lines. The loss-of-function assays were conducted effect on development. Bioinformatics analysis, luciferase reporter gene RIP analysis identify validate target genes AFAP1-AS1. Finally, rescue tests...