A5103280537- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Head and Neck Cancer Studies
- Medical Imaging and Pathology Studies
- Lung Cancer Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Acute Ischemic Stroke Management
- Neuroendocrine Tumor Research Advances
- Gastric Cancer Management and Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Urinary Tract Infections Management
- Colorectal and Anal Carcinomas
- Management of metastatic bone disease
- Esophageal Cancer Research and Treatment
- Reproductive tract infections research
- Sports Performance and Training
- Pelvic floor disorders treatments
- Cancer survivorship and care
- Chronic Obstructive Pulmonary Disease (COPD) Research
- RNA modifications and cancer
- Sports Dynamics and Biomechanics
- Adrenal Hormones and Disorders
- Fatty Acid Research and Health
- Vitamin D Research Studies
Sun Yat-sen University
2018-2025
Sun Yat-sen University Cancer Center
2018-2025
Beijing Sport University
2024
Sichuan University
2016-2024
Zhejiang Chinese Medical University
2024
West China Medical Center of Sichuan University
2023-2024
China Institute of Sport Science
2024
Clinical Trial Investigators
2024
Northeastern University
2024
Chinese University of Hong Kong
2024
Rationale: Interstitial lung abnormalities (ILAs) are being increasingly identified in clinical practice. In particular, for subpleural nonfibrotic ILAs, the risk of progression over time and factors progressive behavior still largely unknown. Objectives: To determine age band prevalence ILAs radiological a large health checkup population to identify how reticulation contributes progression. Methods: On basis definition by Fleischner Society, low-dose chest computed tomography images from...
Abstract Background Despite much research published on lung cancer screening, China has had no large-scale study the missed diagnosis of in a health examination population. We therefore did real-world using current screening guidelines to population determine proportion cases that have been missed. Methods A cohort with use low-dose computed tomography, was conducted among people who took yearly checkup management center West Hospital between 2006 and 2017. respectively used including U.S....
To investigate the incidence of radiation esophagitis (RE) and tumor local control using esophagus sparing technique in locally advanced non-small cell lung cancer (LANSCLC) treated by simultaneous integrated boost intensity-modulated therapy (SIB-IMRT) concurrent chemotherapy.Eighty-seven patients with stage IIIA/B NSCLC who received definitive SIB-IMRT chemotherapy had been divided into two groups: 1.with technique; 2.without technique. Chi-square test was performed to compare sex,...
Purpose Circulating molecules play important roles in lung cancer diagnosis. In addition, plasma lactate dehydrogenase (LDH) and creatine kinase (CK) have been shown to be closely related tumor progression breast cancer, prostate colonel cancer. However, the relationships between LDH CK levels with metastasis occurrence survival status of patients remain unclear. Experimental design A total 1142 were enrolled this study separated into negative or positive groups, according LDH. Patients both...
Whether regular fish oil supplementation is associated with cancer risk controversial. We aimed to evaluate the association of on according fatty consumption patterns. From UK Biobank cohort, 470 804 participants data were included. A total 147 316 individuals in exposed group; other 323 488 unexposed group. No was found between self-report and overall (hazard ratio [HR] = 0.97, 95% confidence intervals [CIs] 0.95-1). Stratified by level, we lower who consumed less than two times per week,...
More attention should be paid to communicable disease-specific infant mortality rate (CD-IMR) in rural China. However, few studies have examined specific geographic patterns and trends CD-IMR these areas. Our aims were assess the epidemiological distribution China for period 1996-2015.We used data from China's Under-5 Child Mortality Surveillance System (U5CMSS). The time IMR assessed by Poisson regression model, proportion of total deaths due disease was Cochran Armitage trend test....
Immune-related cardiotoxicities are uncommon but potentially fatal. The study aims to evaluate the value of pacemakers and methylprednisolone pulse therapy (MPPT) patients with immune-related myocarditis concomitant complete heart block (CHB). We first reviewed medical records three CHB. For pooled analysis, we searched related cases in PubMed database screened patients. Clinical characteristics, management, outcomes were summarized. Our developed CHB about 2 weeks after receiving...
Abstract To compare the LDCT screening results between eligible and ineligible candidates in preventive health check-ups population. Using a real-world among people who took yearly check-up management center of West China Hospital 2006 2017. Objects were classified according to National Lung Cancer Screening Guideline with Low-dose Computed Tomography (2018 version) eligibility criteria. Descriptive analysis performed candidates. The proportion was 64.13% (10,259), them there 4005 (39.04%)...
Objective To establish and validate a model based on hyperdense middle cerebral artery sign (HMCAS) radiomics features for predicting hemorrhagic transformation (HT) in patients with acute ischemic stroke (AIS) after endovascular treatment (EVT). Methods Patients AIS who presented HMCAS non-contrast computed tomography (NCCT) at admission underwent EVT three comprehensive hospitals between June 2020 January 2024 were recruited this retrospective study. A was constructed using the most...
Background Mortality of lung cancer can be decreased by early screening effectively. However, consistent and proficient standards & methods have not been established in China. This study was based on pulmonary nodules/lung comprehensive management platform West China Hospital, Sichuan University. Early nodules integrated into standard healthcare system, aiming to improve survivals patients. Methods Three cohorts were established: healthy populations, cohort patients cohort, related clinical...
The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is a valuable and easy-to-use method for assessing acute ischemic stroke. It aids in identifying suitable candidates thrombolytic therapies evaluating treatment effectiveness. However, ASPECTS evaluation primarily relies on visual observation current clinical practice, lacking common standardized space. Additionally, different doctors may have varying experiences, leading to poor inter-reader agreement potential errors the...
RNA-binding proteins (RBPs) have been reported to be associated with the occurrence and progression of multiple cancers, but role in gastric adenocarcinoma remains poorly understood. The present study aims uncover potential RBPs survival adenocarcinoma, as well corresponding biologic properties signaling pathways these RBPs. RNA sequencing clinical data GC were obtained from Cancer Genome Atlas (n=373) Gene Expression Omnibus (GSE84437, n=433) database. Tumor samples TCGA randomly divided...
Basal ganglia hemorrhage (BGH) is a devastating neurologic disease with high morbidity and mortality, its management still controversial. We evaluated the effectiveness of surgical treatments for BGH investigated computed tomography (CT) imaging features affecting hematoma evacuation rate (ER) in patients treated neuroendoscopic surgery. A total 104 who underwent craniotomy, burr-hole drainage, or surgery were analyzed retrospectively. Clinical characteristics, features, postoperative...
Pulmonary sclerosing hemangioma (PSH) is a relatively rare benign tumor. However, as it occurs only rarely, the natural course of tumor not well understood. In present study, case presented 35-year-old woman who underwent intermittent fevers for more than one year. This highlighted fever symptom PSH. Fever possibly symptoms PSH, although less likely to occur. Another patient was that grew quickly in two months. The lesion diagnosed multiple lung (i.e., PSH), which papillary, solid and...
Objectives To investigate the relationship among baseline health-related quality of life (HRQoL), early changes in HRQoL from to completion first cycle chemotherapy, and prognosis patients with advanced lung cancer. Design This was a prospective, observational study. Setting The study conducted national cancer centre South China. Participants A total 243 chemo-naïve were enrolled. Intervention None. Primary secondary outcome measures Functional Assessment Cancer Therapy-Lung used assess at...
Background: As the incidence continues to rise, global concern about neuroendocrine neoplasms (NENs) is mounting. However, little known how NENs affect women patients. Methods: The annual percentage change (APC) was calculated describe incidence. Cox proportional hazards multivariable regression used identify risk factors. nomograms were employed estimate prognosis. Results: A total of 39,237 female (fNENs) cases identified. fNENs increased annually (APC = 4.5, 95% CI 4.1-4.8, P < 0.05), and...
Hereditary leiomyomatosis and renal cell carcinoma is an uncommon autosomal dominant disease caused by mutations in the fumarate hydratase (FH) gene. They usually demonstrated multiple uterine myomas preformed surgical procedures for myomectomy and/or hysterectomy 10 years earlier than sporadic due to early development. This case report describes a woman with leiomyomas diagnosed FH deficiency.A 37-year-old visited gynecological clinic discovery of leiomyoma more 1 year. The size largest...
Abstract Background Patient follow-up is an essential component of hospital management. In the current information era, patient scheme expected to be replaced by Internet technology. This study constructed a cloud platform for gynecological chemotherapy patients and assessed its cost-effectiveness patients’ feedback. Methods A total 2,538 were followed up using system between January October 2021. Prior this, 690 manually via telephone calls. Patients’ characteristics, rate, satisfaction,...