A5101945543- Gallbladder and Bile Duct Disorders
- Bariatric Surgery and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Appendicitis Diagnosis and Management
- Thyroid and Parathyroid Surgery
- Infection Control and Ventilation
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Cells and Metastasis
- Pancreatitis Pathology and Treatment
- Minimally Invasive Surgical Techniques
- Immune Cell Function and Interaction
- Colorectal Cancer Treatments and Studies
- Hernia repair and management
- Head and Neck Anomalies
- Infection Control in Healthcare
- Body Contouring and Surgery
- Immunotherapy and Immune Responses
- Cancer Research and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Cancer Immunotherapy and Biomarkers
- Tracheal and airway disorders
Capital Medical University
2012-2024
Peking University
2009-2024
Beijing Shijitan Hospital
2012-2024
Nanjing Medical University
2021
Ningbo No.6 Hospital
2017-2018
Nantong University
2017
Peking University International Hospital
2017
Affiliated Hospital of Nantong University
2017
Peking University Third Hospital
2010
Peking Union Medical College Hospital
2010
The aim of this study was to build an artificial neural network (ANN) model for predicting surgery-related pressure injury (SRPI) in cardiovascular surgical patients.Prospective cohort study.One hundred forty-nine patients who had surgery were included the study. This conducted a 1000-bed teaching hospital Eastern China where 250 350 cardiac surgeries are performed each year.We prospective among consecutive undergoing between January and December 2015. ANN built based on possible SRPI risk...
Chemoresistance is one of the main reasons for poor prognosis pancreatic cancer. The effects mesothelin (MSLN) on chemoresistance in cancer are still unclear. We aim to investigate potential roles MSLN and its relationship with proliferation, epithelial-mesenchymal transition (EMT) stemness cells. Human cell lines ASPC-1 Mia PaCa-2 high low expression MSLN, respectively, were selected. knockout (KO) overexpression (OE) generated. phenotypes, EMT-related markers, clone formation, tumor sphere...
Background. Construction of the transcriptional regulatory network can provide additional clues on mechanisms and therapeutic applications in gastric cancer. Methods. Gene expression profiles cancer were downloaded from GEO database for integrated analysis. All DEGs analyzed by GO enrichment KEGG pathway enrichment. Transcription factors further identified then a global was constructed. Results. By analysis six eligible datasets (340 cases 43 controls), bunch 2327 identified, including 2100...
Our purpose was to explore the remission of insulin resistance after bariatric surgery discover mechanism diabetes excluding dietary factors. A retrospective case control study conducted on patients with type 2 diabetes, who underwent laparoscopic sleeve gastrectomy (LSG) or gastric bypass (LGB) in Beijing Shijitan Hospital from April 1, 2012 2013. The laboratory and anthropometric data analyzed pre-surgery during a 2-year follow-up. HOMA-IR calculated evaluated. two surgical procedures were...
Abstract It is undetermined when and how laparoscopic common bile duct exploration (LCBDE) should be used in patients with (CBD) stone-related nonsevere acute cholangitis. We aimed to evaluate the effect of LCBDE on clinical outcome those within (early) or beyond (delayed) 72 hours emergent admission. Surgery-related complications, length hospital stay (LOS) total cost, as well demographic parameters were compared between two groups. Finally, 3 5 early delayed group, respectively, had...
Abstract Background In the past quite a long time, intraoperative cholangiography(IOC)was necessary during laparoscopic cholecystectomy (LC). Now magnetic resonance cholangiopancreatography (MRCP) is main method for diagnosing common bile duct stones (CBDS). Whether MRCP can replace IOC as routine examination before LC still inconclusive. The aim of this study was to analyze clinical data patients undergoing cholecystolithiasis, and explore necessity feasibility preoperative in with...
Abstract Abdominal drainage, serving as a diagnostic and therapeutic tool, has been widely applied to prevent complications after major abdominal surgical procedures. However, dislocation of intraperitoneal portion drainage tube poor surgery never detailed. In this retrospective study, we determined whether postoperative infectious are attributed tube. Patients were recruited from the Department General Surgery at Beijing Shijitan Hospital, Capital Medical University, between June 2015 2018....
Overexpression of CD155 is associated with PD-1 and PD-L1 expression on immune cells, rather than tumor cells in the breast cancer microenvironment
Background: Omohyoid muscle syndrome (OMS) (not omohyoid syndrome) is a rare clinical condition that has characteristic feature of protruding lateral neck mass during swallowing. The use endoscopic surgery on the now pretty well established for thyroid and parathyroid glands. Patients with OMS usually undergo simple surgical transection muscle. procedure leaves operative scars neck, most patients worry about cosmetic problems. We report here first an instead traditional treatment OMS....
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Abstract Matrix metalloproteinase 11 (MMP11), a zinc‐dependent endopeptidase involved in extracellular matrix degradation and remodeling, has been identified as tumor promoter multiple cancer types. However, its expression pattern role pancreatic ductal adenocarcinoma (PDAC) remain unclear. In this study, elevated MMP11 was PDAC tissues associated with diminished survival. Integrated single‐cell RNA sequencing co‐immunofluorescence staining revealed that predominantly expressed...
Colorectal cancer is a common malignancy with high prevalence and associated mortality rate. However, the preclinical tools currently used for drug development are insufficient. The aim of present study was to establish characterize specific patient-derived colon xenograft (PDCCX) mouse model testing. Primary tumors were obtained from 10 patients by surgical resection, tumor tissues subsequently grafted into nude mice followed consecutive passages. collected processed DNA sequencing,...