A5103152225- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Cancer, Hypoxia, and Metabolism
- Organ Donation and Transplantation
- Clinical Nutrition and Gastroenterology
- Neuroendocrine Tumor Research Advances
- Glycosylation and Glycoproteins Research
- Renal cell carcinoma treatment
- Pancreatic and Hepatic Oncology Research
- Renal Transplantation Outcomes and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer-related cognitive impairment studies
- Prenatal Screening and Diagnostics
- Organ and Tissue Transplantation Research
- Autophagy in Disease and Therapy
- Mitochondrial Function and Pathology
- Health and Wellbeing Research
- Cancer survivorship and care
- Nutrition and Health in Aging
- Immunotherapy and Immune Responses
Ajou University
2011-2024
Ajou University Hospital
2005-2020
Although mitochondrial impairment has often been implicated in carcinogenesis, the mechanisms of its development cancer remain unknown. We report here that autophagy triggered by oncogenic K-Ras mediates functional loss mitochondria during cell transformation to overcome an energy deficit resulting from glucose deficiency. When Rat2 cells were infected with a retrovirus harboring constitutively active K-RasV12, respiration significantly declined parallel acquisition characteristics....
Introduction The relationship between a perioperative change in sarcopenic status and clinical outcome of liver transplantation (LT) is unknown. We investigated whether post-LT sarcopenia changes were associated with the survival patients. Method This retrospective study was based on cohort 145 patients from single transplant center who during mean 1 year after LT underwent computed tomography imaging evaluation. cross-sectional area psoas muscle compared that age- sex-matched healthy...
Prophylaxis for hepatitis B virus (HBV) recurrence is essential after liver transplantation (LT) in HBV-associated recipients. We conducted real-world analysis of HBV prophylaxis LT the Korean population.Korean Organ Transplantation Registry (KOTRY) database and additionally collected data (n = 326) were analyzed with special reference to types prophylaxis.The study cohort comprised 267 cases living-donor 59 deceased-donor LT. Hepatocellular carcinoma (HCC) was diagnosed 232 (71.2%) these...
Purpose The aim of this study was to evaluate the multidimensional constructs EORTC Quality Life Questionnaire (QLQ-C30) in patients with cancer, employing not only commonly used multitrait scaling analysis and interscale correlations, but also factorial (MDS) analyses. Materials Methods A total 334 Korean cancer participated cross-sectional study. All completed QLQ-C30. Results With analysis, cognitive functioning scale did meet item convergent divergent validities. physical role scales...
Background Percutaneous biopsy is a widely-accepted technique for acquiring histologic samples of the liver. When there concern bleeding, plugged percutaneous (PPB) may be performed, which involves embolization tract. Purpose To evaluate efficacy and safety PPB liver in patients suspected to have graft rejection after living-donor transplantation (LDLT). Material Methods During January 2007 December 2013, 51 who underwent under suspicion post-LDLT were retrospectively analyzed. A total 73...
Backgrounds/Aims: Prolonged use of steroids after liver transplantation (LT) significantly increases the risk diabetes or cardiovascular disease, which can adversely affect patient outcomes.Our study evaluated effectiveness and safety early steroid withdrawal within first year following LT.Methods: This was conducted as an open-label, multicenter, randomized controlled trial.Liver transplant recipients were randomly assigned to one two groups: Group 1, in withdrawn weeks posttransplantation,...