A5101812719- Cancer Research and Treatments
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Appendicitis Diagnosis and Management
- Virus-based gene therapy research
- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
- Intraperitoneal and Appendiceal Malignancies
- Gastrointestinal Tumor Research and Treatment
- Minimally Invasive Surgical Techniques
- Facial Rejuvenation and Surgery Techniques
- Body Contouring and Surgery
- Colorectal and Anal Carcinomas
- Facial Nerve Paralysis Treatment and Research
- Occupational Health and Safety Research
- Workplace Health and Well-being
- Diverticular Disease and Complications
- Colorectal Cancer Screening and Detection
- Infectious Diseases and Tuberculosis
- Nanoplatforms for cancer theranostics
- Hemodynamic Monitoring and Therapy
- Hernia repair and management
- Cardiac, Anesthesia and Surgical Outcomes
- Diagnosis and treatment of tuberculosis
- Organ Transplantation Techniques and Outcomes
Boramae Medical Center
2024
Seoul National University
2024
Kangdong Sacred Heart Hospital
2011-2023
Hallym University
2011-2023
AntiCancer (United States)
2019-2022
University of California, San Diego
2019-2022
Silla University
2020
Daegu Fatima Hospital
2019
Soonchunhyang University Hospital
2018
Soonchunhyang University
2010-2017
목적: 이 연구의 목적은 우리나라 직장인들의 직무스트레스를 측정하기 위한 신뢰성과 타당성 있는 도구를 개발하고 평가기준 및 참고치를 제시하기 위해 수행되었다. 대상 방법: 연구 대상은 2차의 걸친 표본추출과정에 의해 선정되었다. 1차 표본은 NSDSOS 프로젝트의 수행을 고안된 3개의 광역권에서 조사된 직장인 30, 146명이고, 2차 표준산업분류(대분류 중분류)에 따른 근로자 인구 분포를 고려하여 확률 추출되어 선정된 12, 631명으로 이들을 대상으로 하여 표준화 작업과 규준을 마련하였다. 전문가 회의와 사전조사를 통해 작성된 구조화된 설문지를 이용하여 일반적 특성, 직업적 건강상태(가족력, 질병 과거력 의료이용현황), 직무스트레스 측정도구, 단축형 사회심리적 스트레스(PWI-SF), 피로(MFS) 등을 측정하였다. 그리고 한국인 수준을 측정 평가할 수 표준화된 측정도구와 평가를 성별 도출하였다. 결과: 한국인의 요인으로 간주될 요인을 기존 연구와 외국의 연구결과를 검토...
Baicalein (5,6,7-trihydroxyflavone) is a phenolic flavonoid compound derived mainly from the root of Scutellaria baicalensis Georgi, medicinal plant traditionally used in oriental medicine. In our previous study, baicalein attenuated mitochondrial oxidative stress by scavenging reactive oxygen species (ROS) and induction nuclear factor erythroid 2-related 2 transcription factor-mediated manganese superoxide dismutase. present protective effects against stress-induced damage, especially...
Purpose: Conventional three-port laparoscopic appendectomy (LA) is more commonly performed than transumbilical single port (TUSPLA). In this report, we a prospective randomized study comparing the outcomes of LA and TUSPLA. Methods: Between April 14, 2009 June 10, 2009, 40 patients who required appendectomies were randomly selected to receive either TUSPLA or LA. None these had perforation abscess. Twenty received other 20 The clinical visual analog pain scores (VAS) compared between groups....
The delta neutrophil index (DNI) represents the fraction of circulating immature granulocytes and is a marker infection sepsis. Our objective was to evaluate usefulness DNI for predicting in-hospital mortality within 30 days after surgery in patients with sepsis caused by peritonitis means comparing DNI, white blood cell (WBC) count, percentage, C-reactive protein (CRP) before surgery.We performed retrospective analysis demographic, clinical, laboratory data. WBC CRP were measured surgery,...
Background/Aim: Liver metastasis in colorectal-cancer is a recalcitrant disease. To develop precision individualized therapy of this disease, we developed patient-derived orthotopic xenograft (PDOX) model liver metastasis. In the present report, evaluated efficacy oral recombinant methioninase (o-rMETase) combination with 5-fluorouracil (5-FU) and oxaliplatinum (OXA) on PDOX mouse model. Materials Methods: Colorectal-cancer models were randomized into three groups seven mice. Group 1,...
Hepatocellular carcinoma is one of the most lethal cancers worldwide. More accurate stratification patients at risk necessary to improve its clinical management. As epithelial–mesenchymal transition critical for invasiveness and metastasis human cancers, we investigated expression profiles 12 genes related through a real‐time polymerase chain reaction. From univariate Cox analysis training cohort 128 hepatocellular patients, four candidate (E‐cadherin [ CDH1 ], inhibitor DNA binding 2 ID2...
Colorectal mucosa-associated lymphoid tissue (MALT) lymphoma (cMALToma) is rare and comprises only 2.5% of the MALT lymphomas. Its etiology treatment have not been well established. The aim this systematic literature review was to try characterize cMALToma analyze risk factors for failure with various therapeutic strategies.We retrospectively reviewed 50 case reports from 1993 2017 through a PubMed search English medical literature, describing cMALToma. We included 67 patients previous we...
This study aimed to investigate the impact on nonunion of extent comminution and postoperative displacement in patients surgically treated for subtrochanteric fractures.From 2008 2013, 44 with fractures underwent surgery follow-up. Retrospective data collection showed that it had 32 male 12 female. Their mean age was 45 years. The case distribution according Seinsheimer classification as follows: IIA,8; IIB, 5; IIC, 7; IIIA, 8; IIIB, 3; IV, 9; V, 4. Cephalomedullary nails were used 28 cases;...
The present study aimed to determine if oral methioninase (o-rMETase) combined with oxaliplatinum (OXA) plus 5-fluorouracil (5-FU) increases survival of mice peritoneal-carcinomatosis formed from HCT-116 green fluorescent protein (GFP)-expressing colon-cancer cells implanted intra-peritoneally in nude mice.HCT-116-GFP human (2×106) were injected intraperitoneally athymic mice. Forty-five HCT-116-GFP nude-mouse models divided into the following groups: untreated control; combination 5-FU (50...
The aim of this study was to assess the diagnostic accuracy individual sonographic features and diagnosis for patients with a clinical suspicion tuberculous lymphadenitis in neck.From January 2010 December 2011, 79 who underwent neck sonography sonographically guided fine-needle aspiration tuberculosis polymerase chain reaction analysis were enrolled study. each patient retrospectively investigated by single radiologist using picture archiving communication system, according number...
Surgeons may be uncertain about the optimal timing of appendectomy to decrease complications, especially for complicated appendicitis. The aim study was compare clinical outcomes between early and late surgery appendicitis.A prospectively maintained database appendicitis queried. Elective interval (EIS) group (ES) were matched with propensity score marked a prefix 'p.' Patient characteristics surgical compared.The score-matched EIS had lower chance underwent ileo-cecectomy or right...
Abstract The insertion of a self-expandable metal stent (SEMS) has been proposed as an alternative to emergent surgery (ES) for obstructive colorectal cancer (CRC). We aimed evaluate the perioperative and oncologic outcomes SEMS bridge in CRC, compared with ES. retrospectively reviewed medical records patients who underwent curative resection CRC at four Hallym University-affiliated hospitals between January 2010 December 2019. All were analyzed overall colon, then according side obstruction...
Abstract Background Pressure sores significantly affect elderly patients, with the sacrum being especially vulnerable, often due to its proximity anus and potential for fecal contamination. Despite preventive measures such as frequent repositioning specialized cushions, some still necessitate surgical intervention. Postoperative care focuses on monitoring, hygiene, pressure alleviation. This study assessed efficacy of Closed-Incision Negative Wound Therapy (CI-NPWT) postoperative wound...
The purpose of the present study was to compare perioperative and oncologic outcomes between laparoscopic surgery open for transverse colon cancer.We conducted a retrospective review patients who underwent cancer at six Hallym University-affiliated hospitals January 2005 June 2015. were compared surgery.Of 226 with cancer, 103 123 surgery. There no differences in patient characteristics two groups. Regarding outcomes, operation time significantly longer group than (267.3 vs 172.7 minutes,...
Abstract Although Hartmann’s procedure (HP) is commonly used as emergency treatment for colorectal disease, the reversal of HP (HR) infrequently performed. The aims were to evaluate rate HR and determine factors predictive achieving HR. We retrospectively reviewed medical records patients who underwent between January 2007 June 2019 at six Hallym University-affiliated hospitals. Multivariable analysis was performed identify which independently associated with In study period, 437 HP, 127...