Intussusception is one of the common causes intestinal obstruction in children but uncommon adults. Unlike pediatric intussusception, most adult cases have a demonstrable etiology. The purpose this study was to review our experience intussusception and identify predictive factors for malignancy disease.We retrospectively reviewed medical records patients who were diagnosed with admitted six Hallym University-affiliated hospitals between January 2005 July 2016.The 77 had mean age 50.5 years...

Differentiation-based histologic grading of colorectal carcinoma (CRC) is widely used, but its clinical impact limited by insufficient prognostic value, interobserver disagreement, and the difficulty application to CRC with specific types such as mucinous medullary carcinoma. A recently proposed novel system based on quantifying poorly differentiated clusters (PDCs) claims have advantages reproducibility improved might apply heterogeneous CRC. We aimed validate clinicopathologic significance...

In colorectal carcinoma, poorly differentiated clusters (PDCs) are a poor prognostic indicator and show morphological continuity behavioral similarities to micropapillary patterns (MPPs) as well tumor buds (TBs). Epithelial-mesenchymal transition (EMT) inhibition of cancer-stromal interactions may contribute the development PDCs. To clarify biological nature PDCs, we examined immunohistochemical stainings for β-catenin, Ki-67, E-cadherin, epithelial cell adhesion molecule (EpCAM), MUC1,...

Abstract The insertion of a self-expandable metal stent (SEMS) has been proposed as an alternative to emergent surgery (ES) for obstructive colorectal cancer (CRC). We aimed evaluate the perioperative and oncologic outcomes SEMS bridge in CRC, compared with ES. retrospectively reviewed medical records patients who underwent curative resection CRC at four Hallym University-affiliated hospitals between January 2010 December 2019. All were analyzed overall colon, then according side obstruction...

We applied a long Roux-en-Y (RY) gastrojejunostomy (bypassed jejunum over 100 cm) as reconstruction method for diabetes control to gastric cancer patients with type 2 and body mass index (BMI) < 35 kg/m(2). The effect of this procedure on was assessed.We prospectively performed modified RY gastrojejunostmy after curative radical distal gastrectomy. Thirty had completed 1-year follow-up. Patients were followed concerning their diabetic status. factors included in the investigation length...

This study was designed to retrospectively evaluate the efficacy and safety of modified FOLFOX-6 regimen in advanced gastric cancer (AGC) patients with poor performance status (PS). From January 2005 August 2010, 23 AGC PS who received mFOLFOX-6 as first-line chemotherapy were reviewed. Patients 100 mg/m2 oxaliplatin leucovorin (LV) a 2-h intravenous infusion on day 1, followed by 5-fluorouracil (5-FU) at 2000 46-h continuous infusion. A total 22 more than 3 cycles evaluable for tumor...

Background and objectives: Single-port laparoscopic appendectomy (SLA) in most previous studies has used intracorporeal excision of the appendix needed a longer operative time than multi-port (MLA), although SLA does have potential benefit an almost invisible scar within umbilicus. Some reported that extracorporeal transumbilical single-incision laparoscopic-assisted (TULAA) children took considerably reduced compared to MLA. We adopted TULAA adults, adding routine dissection peritoneal...

Malignant fistula of the small bowel to colon is rare and most often due adenocarcinoma. Small lymphoma unusual, representing less than 1 percent all gastrointestinal malignancies. We report a case intestinal presenting with diarrhea abdominal pain. A jejunocolic was discovered during colonoscopy. Celiotomy revealed large, ulcerated tract between jejunum distal transverse colon, pathology consistent peripheral T-cell lymphoma. This entity in nonimmunocompromised individual has not been...

Background: In recent years, single-incision laparoscopic appendectomy has been used as an improved form of conventional (CLA). We have started to perform gasless laparoscopy-assisted transumbilical (GLATUA) in patients with uncomplicated appendicitis. This study aimed evaluate the feasibility, safety, cosmetic results, and cost-effectiveness this novel technique GLATUA. Patients Methods: total, 30 a diagnosis acute appendicitis without evidence periappendiceal abcess or perforation...

The criterion of two target lesions per organ in the revised Response Evaluation Criteria Solid Tumors version 1.1 (RECIST 1.1) is an arbitrary decision. We assumed that measuring single largest lesion (modified RECIST 1.1, hereafter referred to as mRECIST instead might be enough assess tumor responses.We compared response using computed tomography according and patients with advanced gastric cancer (AGC) who received first-line chemotherapy.A total 51 had at least any were included study....

Elevated levels of serum gastrin (SG) have been associated with tumorigenic effects in a number gastrointestinal cancers. We decided to investigate the relationship between SG and gastric epithelial lesions.A total 90 patients lesions (hyperplastic polyp, 12; adenoma, 41; early cancer, 29; advanced 8) were enrolled as case group 79 without control group.Serum significantly different groups (p<0.001). A high level (>80 pg/mL), intestinal metaplasia, pepsinogen I/II ratio <3 independently an...

The applications of laparoscopic surgery are expanding, but there is still controversy about its application in patients with peritonitis resulting from diverticulitis perforation. This study aimed to investigate the factors affecting postoperative mortality rate undergoing for perforated diverticulitis. Further, we compared recovery courses between open and surgeries.We analyzed medical records adult caused by six hospitals Hallym University Medical Center January 2006 December 2016.A total...

The objective of this study was to compare the long-term prognosis patients with T1 and T2 colorectal cancer (CRC) according lymph node metastasis (LNM) identify risk factors for LNM. We retrospectively reviewed who underwent curative resection or CRC at five University-affiliated hospitals between January 2012 December 2021. were divided into several groups depending on presence LNM number factors. Of total 765 patients, 87 (11.3%) had These poorer recurrence-free survival (RFS) than...

See Article on Page 31-40 In recent years, a number of studies the use preoperative chemoradiotherapy (CRT) in patients with cT3-4 rectal cancer have reported pathologically complete response rate 9-29%, as well an increased ability to perform sphincter-sparing surgery [1, 2]. Preoperative CRT is superior postoperative treatment terms local control and toxicity [3]. In Swedish Rectal Cancer Trial, recurrence was 27% alone, 20% radiation (60 Gy 8 weeks) 11% (25 5 fractions) [4]. There also...

See Article on Page 16-22 Due to the significant improvement in minimal invasive surgery, a large group of surgeons has focused cosmetic results and minimization number size ports. In addition, single-incision laparoscopic colectomy was recently introduced reduce patient's trauma related with conventional multiport approaches. colectomy, all trocars are inserted through one umbilical incision. However, published studies limited, for most part, right colon [1] sigmoid [2], surgery field...

See Article on Page 216-221 In the past, majority of acute complicated diverticulitis patients were managed by using surgical intervention, such as a resection perforated bowel and creation an end colostomy. However, intervention in cases is associated with high postoperative morbidity mortality [1]. Although optimal treatment for controversial, recently, evolution techniques supportive medical care, advances development antibiotics, interventional radiology techniques, parenteral...

See Article on Page 27-32 In recent years, many patients with rectal cancer have been surgically treated using a low anterior resection. The resection has become the operation of choice for mid or lower cancer. A number studies use to treat reported results in terms oncologic outcomes and quality life (QoL). majority are sphincter-sparing surgery such as resection, 50% 90% those experience bowel dysfunction, known syndrome [1]. Surgeons consider not only surgical methods treating but also...

Purpose: Ductal carcinoma in situ (DCIS), unlike invasive ductal carcinoma, does not require sentinel lymph node biopsy or axillary dissection because the possibility of metastasis is low. However, occasionally, despite preoperative diagnosis DCIS, can be diagnosed by postoperative biopsy. Therefore, a study associated risk factors necessary. Methods: 198 patients with an initial treated between February 2005 and December 2009, were retrospectively analyzed. Associations clinical pathologic...

This study was conducted to evaluate the efficacy and safety of combination mitomycin-C (MMC) S-1 as third-line chemotherapy for patients with advanced colorectal cancer (CRC) showing resistance irinotecan- oxaliplatin-containing regimens. Patients were recruited into from January 2009 10 enrolled months. However, since no had shown a response by months, terminated early according protocol. MMC 7 mg/m(2) administered intravenously on day 1 every 6 weeks in first 4 cycles. twice daily at 35...

Background: The objective of this study was to evaluate clinicopathologic features young patients with colorectal cancer (CRC) and compare their prognosis those older Methods: We retrospectively reviewed the medical records who underwent surgery for stage 0–III CRC at four university-affiliated hospitals between January 2011 December 2020. were divided into two groups, adult group (≤45 years) (&gt;45 years). Results: Of 1992 patients, 93 (4.6%) adults 1899 (95.3%) patients. Young showed more...