A5100359904- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Voice and Speech Disorders
- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Head and Neck Cancer Studies
- Salivary Gland Disorders and Functions
- Salivary Gland Tumors Diagnosis and Treatment
- Respiratory and Cough-Related Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Histone Deacetylase Inhibitors Research
- Effects of Radiation Exposure
- Radiomics and Machine Learning in Medical Imaging
- Oral Health Pathology and Treatment
- PI3K/AKT/mTOR signaling in cancer
- Sphingolipid Metabolism and Signaling
- Parkinson's Disease Mechanisms and Treatments
- Neuroendocrine Tumor Research Advances
- Neurological disorders and treatments
- Cardiovascular and Diving-Related Complications
- Glycosylation and Glycoproteins Research
- Health, psychology, and well-being
- Monoclonal and Polyclonal Antibodies Research
- Acute Ischemic Stroke Management
- Cancer, Hypoxia, and Metabolism
Inha University
2018-2025
Chungnam National University
2025
University of Ulsan
2013-2024
Ulsan College
2014-2024
Pohang University of Science and Technology
2019-2024
Kyung Hee University
2024
Kyung Hee University Medical Center
2024
Kyung Hee University Hospital at Gangdong
2024
Asan Medical Center
2014-2024
Boramae Medical Center
2014-2024
Dysphagia is a common clinical condition characterized by difficulty in swallowing. It sub-classified into oropharyngeal dysphagia, which refers to problems the mouth and pharynx, esophageal body esophagogastric junction. can have significant negative impact one's physical health quality of life as its severity increases. Therefore, proper assessment management dysphagia are critical for improving swallowing function preventing complications. Thus guideline was developed provide...
E-cigarettes, also known as electronic nicotine delivery systems and cigarettes, are advertised a healthier alternative product to tobacco cigarettes despite limited data on the consequences of e-cigarette use. Currently, there no US Food Drug Administration or other federal regulations e-cigarettes, calls poison control centers regarding liquid toxicity, especially in children, rise. This article presents background mechanism action e-cigarettes well up-to-date details toxicity nicotine. We...
No potential conflict of interest relevant to this article was reported. Highlights1. NTPAM therapy activates the ROS and cell death pathways in RR-HNSCC cells.2. regulates associated with radiation resistance lines.3. ABCC3, DUSP16, PDGFB, RAF1, THBS1 may serve as novel biomarkers for treatment cells.4. targets ECM, TGF-β, PI3K-AKT, MET pathways, providing insights into reversing RR-HNSCC.
The treatment of laryngeal cancer requires clinical decision-making that balances survival outcomes with the preservation essential functions such as voice and swallowing. study, led by Clinical Practice Guideline Committee Korean Society Head Neck Surgery, aims to establish evidence-based recommendations guide optimal decisions for patients from surgeons' perspectives. A literature search was conducted in PubMed, Embase, Cochrane Library, KoreaMed databases a expert reviewed panel 39...
The aim of this study was to investigate the role psychosocial problems and their associations with rotating shift work in development functional gastrointestinal disorders.In cross-sectional observation study, survey administered nurses nurse assistants a referral hospital. In addi-tion demographic questions, subjects were asked complete Rome III Questionnaire, Pittsburgh Sleep Quality Index Psychosocial Alarm Questionnaire.Responses from 301 assessed. overall prevalence irritable bowel...
Vocal cord paralysis caused by recurrent laryngeal nerve (RLN) injury during thyroidectomy results in hoarseness, aspiration, and dyspnea. We evaluated the usefulness of guidance conduits (NGCs) constructed from an asymmetric polycaprolactone (PCL)/Pluronic F127 porous membrane filled with platelet-rich plasma (PRP) for functional RLN regeneration. proliferation migration Schwann cells (SCs) after PRP treatment vitro. For vivo study, rabbits were divided into a non-loaded NGC group...
Abstract Building a sophisticated protein nano-assembly requires method for linking components in predictable and stable structure. Diabodies are engineered antibody fragments that composed of two Fv domains connected by short peptide linkers. They attractive candidates mediators assembling nano-structures because they can simultaneously bind to different proteins rigid enough be crystallized. However, comparison previous crystal structures demonstrates there is substantial structural...
Abstract After radioiodine (RI) therapy, patients with thyroid cancer frequently suffer from painful salivary gland (SG) swelling, xerostomia, taste alterations, and oral infections. This study was aimed to determine whether adipose-derived mesenchymal stem cells (AdMSCs) might restore RI-induced SG dysfunction in a murine model. Forty -five mice were divided into three groups; PBS sham group, RI+ group (0.01 mCi/g mouse, orally), an RI+AdMSCs (1 × 10 5 cells/150 uL, intraglandular injection...
Background: Papillary thyroid carcinoma (PTC) is generally an indolent tumor that has a favorable prognosis. However, locally invasive PTC can recur after treatment, and its optimal treatment still controversial. This study aimed to evaluate outcomes identify risk factors for recurrence survival in patients with PTC. Materials Methods: All consecutive who underwent definitive surgery radioactive iodine therapy non-distant metastatic were included. Clinical factors, operative pathological...
Purpose: The purpose of this study was to determine the prevalence ocular hypertension (OHT) and open-angle glaucoma (OAG) in patients with Graves' orbitopathy (GO) investigate associations between clinical features disease OHT OAG. Methods: A cross-sectional analytic conducted among a total 1128 GO. complete ophthalmic examination performed, including intraocular pressure, optic disc photography, visual field testing using Humphrey analyzer, retinal nerve fiber layer thickness measured by...
Abstract The sodium-dependent citrate transporter of Klebsiella pneumoniae ( Kp CitS) belongs to the 2-hydroxycarboxylate (2-HCT) family and allows cell use as sole carbon energy source in anaerobic conditions. Here we present crystal structures CitS citrate-bound outward-facing, asymmetric, citrate-free inward-facing state. reveal that dimerization domain remains stationary throughout transport cycle due a hydrogen bond network well extensive hydrophobic interactions. In contrast, its...
Voice change is a common complaint after thyroid surgery and has significant impact on quality of life. The Korean Society Laryngology, Phoniatrics Logopedics assembled task force to establish guideline recommendations education, care, management related surgery. encompass preoperative voice anticipated during surgery, comprehensive care include in-depth information up-to-date knowledge based validated literature. committee constructed 14 key questions (KQs) in three categories-preoperative...
In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of disease. We investigated cardiac sympathetic dysfunction using (123)I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy 22 patients with ET, comparison PD and tremor-dominant (TDPD). The mean ratio (123)I-MIBG uptake region interest heart that mediastinum (H/M ratio) was significantly greater ET (1.99 +/- 0.21) than those either TDPD (1.28 0.11) or 0.17;...
Antibodies are indispensable tools in protein engineering and structural biology. suitable for studies should recognize the 3-dimensional (3D) conformations of target proteins. Generating such antibodies characterizing their complexes with antigens take a significant amount time effort. Here, we show that can expand application well-characterized by “transplanting” epitopes they to proteins completely different structures sequences. Previously, several have been shown alpha-helical...