Ji-Hye Kwak

ORCID: 0000-0003-3063-7603
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About
Contact & Profiles
Research Areas
  • Erythrocyte Function and Pathophysiology
  • Blood disorders and treatments
  • Facial Nerve Paralysis Treatment and Research
  • Meningioma and schwannoma management
  • Autism Spectrum Disorder Research
  • Autophagy in Disease and Therapy
  • Neurogenesis and neuroplasticity mechanisms
  • Head and Neck Cancer Studies
  • Cervical Cancer and HPV Research
  • Pluripotent Stem Cells Research
  • Cancer Diagnosis and Treatment
  • Salivary Gland Tumors Diagnosis and Treatment

Kyungpook National University
2020-2024

The treatment of laryngeal cancer requires clinical decision-making that balances survival outcomes with the preservation essential functions such as voice and swallowing. study, led by Clinical Practice Guideline Committee Korean Society Head Neck Surgery, aims to establish evidence-based recommendations guide optimal decisions for patients from surgeons' perspectives. A literature search was conducted in PubMed, Embase, Cochrane Library, KoreaMed databases a expert reviewed panel 39...

10.21053/ceo.2025.00009 article EN cc-by-nc Clinical and Experimental Otorhinolaryngology 2025-04-08

Background/Objectives: To evaluate the role of postoperative radiotherapy (PORT) in management localized head and neck mucosal melanoma (HNMM). Methods: We retrospectively reviewed 33 patients who underwent surgery for HNMM between 2006 2023. PORT was delivered to affected anatomical structures, elective nodal irradiation not performed. Treatment outcomes, including local recurrence-free survival (LRFS), progression-free (PFS), overall (OS), were analyzed. Results: After surgery, 14 (41.4%)...

10.3390/cancers17081284 article EN Cancers 2025-04-10

Heterogeneity in the etiopathology of autism spectrum disorders (ASD) limits development generic remedies, requires individualistic and patient-specific research. Recent progress human-induced pluripotent stem cell (iPSC) technology provides a novel platform for modeling ASDs studying complex neuronal phenotypes. In this study, we generated telencephalic induced (iN) cells from iPSCs derived an ASD patient with heterozygous point mutation DSCAM gene. The mRNA density dendrites were...

10.1038/s41380-021-01216-9 article EN cc-by Molecular Psychiatry 2021-07-12

Human papillomavirus (HPV) infection has emerged as an etiologic factor of squamous papilloma (SP). The oropharynx and larynx are common sites SP, but studies on the prevalence HPV in these lacking. This study aimed to evaluate compare characteristics oropharyngeal SP (OPSP) laryngeal (LSP). detection genotyping data patients with pathologically confirmed OPSP LSP were retrospectively analyzed. A total 119 enrolled, consisting 93 26 LSP. Of those patients, 13 14 positive for infection,...

10.3390/diagnostics14111163 article EN cc-by Diagnostics 2024-05-31

Abstract Significant clinical symptoms of Cohen syndrome (CS), a rare autosomal recessive disorder, include intellectual disability, facial dysmorphism, postnatal microcephaly, retinal dystrophy, and intermittent neutropenia. CS has been associated with mutations in the VPS13B (vacuolar protein sorting 13 homolog B) gene, which regulates vesicle-mediated transport; however, cellular mechanism underlying pathogenesis patient-derived neurons remains uncertain. This report states that...

10.1186/s13041-020-00611-7 article EN cc-by Molecular Brain 2020-05-06

This study aimed to evaluate the current practices and trends of intraoperative facial nerve (FN) monitoring (IOFNM) during parotidectomy.

10.3390/diagnostics14202277 article EN cc-by Diagnostics 2024-10-13
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