A5052819460- Dysphagia Assessment and Management
- Head and Neck Cancer Studies
- Voice and Speech Disorders
- Lymphoma Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Thyroid Cancer Diagnosis and Treatment
- Respiratory and Cough-Related Research
- Oral and Maxillofacial Pathology
- RNA modifications and cancer
- Tracheal and airway disorders
- Cancer-related molecular mechanisms research
- Nutrition and Health in Aging
- Ear Surgery and Otitis Media
- Viral-associated cancers and disorders
- Vestibular and auditory disorders
- Genetic factors in colorectal cancer
- Oral and gingival health research
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Renal Diseases and Glomerulopathies
- Trigeminal Neuralgia and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Chronic Lymphocytic Leukemia Research
- Facial Nerve Paralysis Treatment and Research
Eulji University
2020-2024
Eulji University Hospital
2021-2024
Eulji General Hospital
2023
University of Ulsan
2018-2021
Asan Medical Center
2018-2021
Ulsan College
2018-2021
Kyung Hee University
2015-2020
Seoul National University Hospital
2018
Kyung Hee University Medical Center
2017
Klinikum rechts der Isar
2011
Abstract In this study we assessed the clinical significance of an epithelial-mesenchymal transition (EMT) gene signature and explored its association with tumor microenvironment related to immunotherapy in patients head neck squamous cell carcinoma (HNSCC). Genes were selected when mRNA levels positively or negatively correlated at least one well-known EMT marker. We developed consisting 82 genes. The classified into epithelial mesenchymal subgroups according signature. was validated three...
The treatment of laryngeal cancer requires clinical decision-making that balances survival outcomes with the preservation essential functions such as voice and swallowing. study, led by Clinical Practice Guideline Committee Korean Society Head Neck Surgery, aims to establish evidence-based recommendations guide optimal decisions for patients from surgeons' perspectives. A literature search was conducted in PubMed, Embase, Cochrane Library, KoreaMed databases a expert reviewed panel 39...
To analyze laryngopharyngeal reflux (LPR) as an acidic, nonacidic, or mixed type according to 24-hour multi-channel intraluminal impedance (MII) pH monitoring and the clinical characteristics of each type.Ninety patients were prospectively enrolled in this study. All underwent MII a diagnostic tool. Eighty-three diagnosed with LPR. The classified into three groups hypopharyngeal probe: acid group, nonacid group. Subjective symptoms objective findings evaluated based on patients' responses...
SOX2 copy number and mRNA expression were analysed to examine the clinical significance of activation in HNSCC. Gene signatures reflecting identified an HNSCC cohort. Patients with classified into two subgroups according gene signature: SOX2-high SOX2-low. The was further validated independent cohorts. Moreover, response radiotherapy assessed patients relationship between vitro experiment. subgroup had a better prognosis than SOX2-low all three patient Results multivariate regression...
Conclusion: Factors prognostic of recovery from low frequency sensorineural hearing loss without vertigo are co-occurrence tinnitus, PTA determined level on the affected side before treatment initiation, and time onset to initiation. The rate was higher in oral steroid than intra-tympanic combined groups. Objectives: Although many studies have assessed acute sudden loss, few analyzed low-frequency loss. Clinical characteristics patients with may vary by type This study, therefore, clinical...
We evaluated real-world effectiveness and safety of CT-P10 (Truxima®) compared with originator rituximab in diffuse large B-cell lymphoma (DLBCL) treatment. Before after the introduction to our institute (November 2017), 221 newly-diagnosed DLBCL patients received standard cyclophosphamide, vincristine, doxorubicin prednisone. Patients throughout (n = 95), switched from 36), or 90). There were no significant differences between groups overall response rate (91.6% vs 94.4% 96.7%,...
Background and Objectives To investigate whether taste thresholds, as determined by electrogustometry (EGM) chemical tests, differ age the severity of facial palsy in patients with Bell's palsy. Subjects Methods This study included 29 diagnosed between January 2014 May 2015 our hospital. Patients were assorted into groups palsy, House-Brackmann Scale, their thresholds assessed EGM tests. Results showed that at four locations on tongue one location central soft palate, 1 cm from palatine...
Although the genetic alteration of CUB and Sushi multiple domains 1 (CSMD1) is known to be associated with poor prognosis in several cancers, there a lack clinical relevance head neck cancer. The aim this study was offer insight into significance CSMD1, utilizing multimodal approach that leverages publicly available independent genome-wide expression datasets. CSMD1-related genes were found analyzed examine CSMD1 inactivation HNSCC cohort databases. We frequency somatic mutations,...
Granulomatosis with polyangiitisis [(GPA) or Wegener granulomatosis] is a multi-system disease characterized by granuloma formation and necrotizing vasculitis. GPA classically shows involvement of the respiratory tracts renal system. However, locoregional common may include otologic manifestations. Although can occur during course GPA, no report has described facial palsy sudden sensorineural total deafness vertigo as presenting feature GPA. This case describes patient multiorgan involving...
To determine the effect of a postoperative proton pump inhibitor (PPI) on voice outcomes after phonomicrosurgery in patients with vocal fold polyp.This is prospective, randomized controlled study.This study was carried out tertiary care referral medical centre.A total 48 underwent for polyps. After surgery, were to PPI group (lansoprazole 15 mg twice daily 2 months) and non-PPI group.Voice handicap index (VHI) perceptual acoustic analysis evaluated at baseline months surgery.Among enrolled...
To examine the factors which affect improvement or recurrence of disease after intralesional steroid injection in patients with oral lichen planus (OLP).Sixty-two diagnosed as OLP were treated intralesion corticosteroid injection. evaluate objective severity OLP, total score was assessed. affecting therapeutic effect injection, compared between symptom-improved group and symptom-not-improved group. assess symptom patients, filled 10-cm visual analogue scale, along an Oral Health Impact...
Extranodal natural killer T cell lymphoma (ENKTL) is a rare subtype of non-Hodgkin with invariable infection cells Epstein-Barr virus (EBV), and the presence EBV-DNA in blood well-known prognosticator. However, there no consensus on which compartment more optimal for predicting survival outcomes.We analyzed 60 patients who were newly diagnosed ENKTL from prospectively collected database. was measured whole-blood (WB) plasma at time diagnosis after treatment completion.EBV-DNA detected...
Abstract The role of the Epstein-Barr virus (EBV) status in blood for predicting survival post-transplantation lymphoproliferative disorders–diffuse large B-cell lymphoma (PTLD–DLBCL) is unknown. We evaluated prognostic values pre-treatment EBV-encoded small RNA (EBER) detected with situ hybridization tissues and EBV DNA whole (WB) plasma 58 patients monomorphic PTLD–DLBCL after solid organ transplantation. There were no significant differences rates overall response, complete according to...