A5078365038- Neurological disorders and treatments
- Neurological and metabolic disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Genetic Neurodegenerative Diseases
- Nutrition and Health in Aging
- Thyroid Cancer Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Alzheimer's disease research and treatments
- Cancer survivorship and care
- Diet and metabolism studies
- Lung Cancer Treatments and Mutations
- Dementia and Cognitive Impairment Research
- Intracerebral and Subarachnoid Hemorrhage Research
- TGF-β signaling in diseases
- Cancer, Hypoxia, and Metabolism
- Oropharyngeal Anatomy and Pathologies
- Renal Diseases and Glomerulopathies
- Cancer, Lipids, and Metabolism
- Sarcoma Diagnosis and Treatment
- Botulinum Toxin and Related Neurological Disorders
- Glioma Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
Kyung Hee University
2014-2023
Kyung Hee University Dental Hospital
2021
Kyung Hee University Medical Center
2013-2020
Asan Medical Center
2006-2014
University of Ulsan
2006-2014
Ulsan College
2006-2014
Kyung Hee University Hospital at Gangdong
2011
Barcelona Clinic Liver Cancer (BCLC) stage C hepatocellular carcinoma (HCC) consists of a heterogeneous group patients with wide range survival times, requiring further prognostic stratification to facilitate treatment allocation. We evaluated the value <sup>18</sup>F-FDG uptake on PET/CT at time presentation in BCLC HCC. <b>Methods:</b> A total 291 HCC who underwent between 2009 and 2010 for staging were retrospectively enrolled from 7 university hospitals. The divided into 2 groups...
This study aimed to assess the prognostic value of <sup>18</sup>F-FDG uptake in hepatocellular carcinoma (HCC) patients who had transarterial chemoembolization (TACE) or concurrent intraarterial chemotherapy with external-beam radiotherapy (CCRT) and compare prognosis between treated TACE those CCRT according uptake. <b>Methods:</b> Two hundred fourteen intermediate–to–advanced-stage HCC without extrahepatic metastasis underwent staging PET/CT before (153 patients) (61 were recruited from 7...
Abstract Background Cancer cachexia (CC) is a multifactorial process characterized by progressive weight loss, muscle mass, and fat tissue wasting, which adversely affects the quality of life survival patients with advanced stages cancer. CC has complex pathophysiology, there no established standard treatment. Therefore, it often irreversible single treatment modality unlikely to suppress its progression. We are conducting randomized trial investigate efficacy safety multimodal intervention...
Paresis of the upper extremity after stroke is not effectively solved by existing therapies. We investigated whether mental imagery training combined with electromyogram-triggered electric stimulation improved motor function paretic in patients chronic and induced cortical changes.Fourteen subjects (≥12 months) were randomly allocated to receive (n=7) or generalized functional on forearm extensor muscles 2 20-minute daily sessions 5 days a week for 4 weeks. The component Fugl-Meyer Motor...
Mediastinal lymph node (LN) staging in individuals with non-small-cell lung cancer plays an important role and treatment planning. This study aimed to assess the accuracy of computed tomography (CT) texture analysis (CTTA) differentiating benign malignant mediastinal LNs. Pathologically confirmed LN samples, obtained using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), were retrospectively reviewed, addition chest CT 18-fluorodeoxyglucose (FDG) uptake positron...
The clinical implications of the metabolic parameters 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) in epidermal growth factor receptor (EGFR)-mutated lung cancer are not fully understood. aim this study was to evaluate diagnostic and prognostic utility EGFR-mutated patients.We retrospectively enrolled 134 patients with advanced adenocarcinoma (72 EGFR-negative 62 EGFR-positive). We evaluated correlation between EGFR mutational status maximum...
Objective We evaluated the diagnostic usefulness of 3′-deoxy-3′-[18F]fluorothymidine (FLT) compared with 2-[18F]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) in recurrent brain tumors. Methods Twenty patients suspected recurrence after surgical removal primary tumors were studied. The uptake was assessed visually and quantified by standardized value (SUV) SUV ratio tumor to white matter, gray normal tissue. Final diagnoses made histopathology or clinical radiological...
Among the apoptosis signals, B-cell CLL/lymphoma 2 (BCL2) is a well-known regulator of with anti-apoptotic properties. We investigated here whether single nucleotide polymorphisms (SNPs) BCL2 were associated host susceptibility papillary thyroid cancer (PTC) occurrence and clinicopathologic parameters.Ninety-two PTC patients 222 control subjects recruited. One promoter SNP (rs2279115, -938A/C) one synonymous (rs1801018, Thr7Thr) in gene selected genotyped using direct sequencing. Multiple...
The study aims to evaluate whether bone scintigraphy is effective in diagnosing temporomandibular joint (TMJ) osteoarthritis (OA) juvenile patients. A retrospective was conducted with 356 consecutive patients TMJ-OA who were clinically assessed according the Research Diagnostic Criteria for Temporomandibular Disorders. Patients assigned three groups based on their ages: Group 1: aged 12-16 years; 2: 17-19 and 3: 20 years. Additionally, we performed qualitative quantitative analyses of images...
Objective: To investigate the association between plasma amyloid-β (Aβ) levels and neuropsychological performance in patients with cognitive decline using a highly sensitive nano-biosensing platform. Methods: We prospectively recruited 44 who underwent Aβ analysis, amyloid positron emission tomography (PET) scanning, detailed tests. Patients were classified into normal control (NC, n = 25) or Alzheimer's disease (AD, 19) group based on PET positivity. Multiple linear regression was performed...
The radiological and clinical significance of a dilated Virchow-Robin space (dVRS) in the striatum (STR) remains unclear. We investigated role dVRS STR on parkinsonism dopamine transporter positron emission tomography (DaT-PET) findings.Patients with who underwent both brain magnetic resonance imaging DaT-PET were included. Clinical status was evaluated by Hoehn Yahr (HY) stage, Korean-Mini Mental Status Examination (K-MMSE), Montreal Cognitive Assessment Korea (MoCA-K), Frontal Battery...
To assess the accuracy of a combination CT texture analysis (CTTA) and nodal axial ratio to detect metastatic lymph nodes (LNs) in esophageal squamous cell carcinoma (ESCC).The contrast-enhanced chest images 78 LNs (40 metastasis, 38 benign) from patients with ESCC were retrospectively analyzed. Nodal ratios (short-axis/long-axis diameter) calculated. CCTA parameters (kurtosis, entropy, skewness) extracted using commercial software (TexRAD) fine, medium, coarse spatial filters. Combinations...
Collagen type XI α1 (COL11A1) gene overexpression has been implicated as a candidate marker of various types cancers. In this study, we investigated whether coding region single nucleotide polymorphisms (cSNPs) the COL11A1 are associated with papillary thyroid cancer (PTC) in Korean population. Four cSNPs [rs12731843 (Lys276Asn), rs3753841 (Pro1335Leu), rs1763347 (Gly1516Gly) and rs2229783 (Ile1602Ile)] were genotyped using direct sequencing 98 PTC patients 366 control subjects. Logistic...
To investigate the association between papillary thyroid cancer (PTC) and single nucleotide polymorphisms (SNPs) of oncostatin M receptor (OSMR) in Korean population.Retrospective case-control study was done. Eighty-five patients with PTC 287 controls were studied. One missense SNP (rs2278329, Asp553Asn) one promoter (rs2292016, -100 G/T) OSMR gene genotyped by direct sequencing. Genetic data analyzed using SNPStats, Helixtree, SNPAnalyzer Pro. dichotomized compared respect to...
The aim of this study was to compare the diagnostic performance [(18)F]fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) with that sonography and sonographically guided fine-needle aspiration (FNA) for determining preoperative axillary lymph node (ALN) status evaluate factors related false-negative PET-CT, sonographic, FNA results in ALN staging invasive ductal carcinoma.From March 2009 July 2012, 226 patients had a diagnosis primary breast cancer. Among...