A5100761909- Radiomics and Machine Learning in Medical Imaging
- Cancer-related molecular mechanisms research
- Plasma Applications and Diagnostics
- Lung Cancer Treatments and Mutations
- Metastasis and carcinoma case studies
- Breast Cancer Treatment Studies
- MRI in cancer diagnosis
- Cancer-related gene regulation
- MicroRNA in disease regulation
- Lung Cancer Diagnosis and Treatment
- Circular RNAs in diseases
- Glioma Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Metabolism, Diabetes, and Cancer
- Sexual function and dysfunction studies
- Renal cell carcinoma treatment
- Inflammatory Biomarkers in Disease Prognosis
- Ferroptosis and cancer prognosis
- Advanced Nanomaterials in Catalysis
- Breast Lesions and Carcinomas
- Autophagy in Disease and Therapy
- Nitric Oxide and Endothelin Effects
- Economic and Financial Impacts of Cancer
- Cancer Treatment and Pharmacology
- Cardiac Imaging and Diagnostics
Chungnam National University
2015-2025
Chungnam National University Hospital
2023-2025
National University College
2021
New Generation University College
2021
Shaikh Khalifa Medical City
2015
Seoul National University Hospital
2008
Yonsei University
2006
Seoul National University
2001
The University of Texas Medical Branch at Galveston
1978
No potential conflict of interest relevant to this article was reported. Highlights1. NTPAM therapy activates the ROS and cell death pathways in RR-HNSCC cells.2. regulates associated with radiation resistance lines.3. ABCC3, DUSP16, PDGFB, RAF1, THBS1 may serve as novel biomarkers for treatment cells.4. targets ECM, TGF-β, PI3K-AKT, MET pathways, providing insights into reversing RR-HNSCC.
Objective: Bronchogenic carcinoma can mimic or be masked by pulmonary tuberculosis (TB), and the aim of this study was to describe radiologic findings clinical significance bronchogenic TB which coexist in same lobe. Materials Methods:The 51 patients (48 males three females, aged 48-79 years) whom coexisted lobe were analyzed.The morphologic characteristics a tumor, such as its diameter margin, presence calcification cavitation, mediastinal lymphadenopathy, seen at CT, retrospectively...
Objectives Despite a sharp increase in e-cigarette use, there is debate about whether e-cigarettes are viable alternative for harm reduction, and the forms that regulation should take. Healthcare providers can be effective offering guidance to patients their families shaping regulatory policy. We described lung cancer specialists' attitudes toward its regulation. Methods undertook nationwide survey of pulmonologists, thoracic surgeons, medical radiological oncologists who members Korean...
(1) Background: Nonthermal plasma (NTP) induces cell death in various types of cancer cells, providing a promising alternative treatment strategy. Although recent studies have identified new mechanisms NTP several cancers, the molecular underlying its therapeutic effect on thyroid (THCA) not been elucidated. (2) Methods: To investigate mechanism NTP-induced death, THCA lines were treated with NTP-activated medium -(NTPAM), and gene expression profiles evaluated using RNA sequencing. (3)...
Objectives. The mitochondrial ribosomal protein L14 (MRPL14) is encoded by a nuclear gene and participates in translation. In this study, we aimed to investigate the role of MRPL14 thyroid cancer.Methods. We investigated association between expression clinicopathological features using Cancer Genome Atlas (TCGA) Chungnam National University Hospital (CNUH) databases. Functional studies MRPL14, including proliferation, migration, invasion, oxidative phosphorylation reactive oxygen species...
The purpose of this study was to assess the incidence invasive lobular carcinoma (ILC) and compare clinicopathological features treatment results after breast conserving surgery (BCS) followed by radiotherapy between ILC ductal (IDC).A total 1,071 patients who underwent BCS were included in study. Medical records pathological reports retrospectively reviewed.The 5.2% (n=56). Bilateral cancer, lower nuclear grade, hormone receptor-positive cancer more frequent with than those IDC. There no...
Locoregional treatment has been increasingly adopted for metastatic breast cancer at presentation. This study aims to develop an individualized calculator predict the benefit of postoperative radiotherapy (PORT) patients with surgically resected de novo stage IV cancer. We searched Surveillance, Epidemiology, and End Results (SEER) database diagnosed between 2010 2014. After applying exclusion criteria, a total 4473 were included in analysis. Propensity score matching was used balance...
We investigated the incidence of renal function impairment after adjuvant treatment for gastric cancer and analyzed impact radiotherapy on estimated glomerular filtration rate (eGFR) five years surgery. reviewed medical records 1490 patients with stomach who underwent curative surgery cancer. Finally, we included 663 were followed up ≥5 without disease recurrence whose baseline eGFR was ≥60 mL/min/1.73 m2. Logistic linear regression analyses performed to determine independent factors...
Lung cancer specialists play an important role in designing and implementing lung screening. We aimed to describe their 1) attitudes toward low-dose computed tomography (LDCT) screening, 2) current practices experiences of LDCT screening 3) opinions towards national program (NLCSP). conducted a web-based survey pulmonologists, thoracic surgeons, medical oncologists, radiological oncologists who are members Korean Association for Cancer (N = 183). Almost all respondents agreed that increases...
To evaluate the utility of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) using macromolecular contrast agent (P792) for assessment vascular disrupting drug effect in rabbit VX2 liver tumor models.This study was approved by our Institutional Animal Care and Use Committee. DCE-MRI performed with 3-T scanner 13 tumor-bearing rabbits, before, 4 hours after, 24 after administration (VDA), gadomelitol (P792, n = 7) or low molecular weight (gadoterate meglumine [Gd-DOTA], 6). P792...
Mitochondrial targeted therapy is a next‐generation therapeutic approach for cancer that refractory to conventional treatments. damage caused by the excessive accumulation of reactive oxygen species (ROS) principle mitochondrial therapy. ROS in nonthermal plasma‐activated media (NTPAM) are known mediate anticancer effects various cancers including head and neck (HNC). However, signaling mechanism HNC cell death via NTPAM‐induced has not been fully elucidated. This study evaluated NTPAM...
Growing evidence suggests that metastasis-directed therapy and/or prostate-directed may benefit patients with oligometastatic prostate cancer (OMPC). Stereotactic body radiotherapy (SBRT) is increasingly used to treat oligometastases in various cancers. The purpose of this study was investigate the current patterns curative-intent SBRT for OMPC Korea.A 20-item questionnaire sent 326 radiation oncologists 93 institutions Korea. Only 1 physician per institution required complete survey....
<title>Abstract</title> Dysregulation of microRNAs (miRNAs) influences diverse hallmarks cancer, including proliferative signaling, metastasis, and resistance to cell death. We explored the contribution miR-92b-3p in oral squamous carcinoma (OSCC) its potential as a monitoring biomarker. Analysis TCGA, GEO, our own cohort revealed dysregulation OSCC, which correlated with aggressive tumor characteristics. overexpression augmented proliferation epithelial-mesenchymal transition both YD8 SCC25...
(1) Background: P-cadherin (CDH3) is a transmembrane protein that plays crucial role in maintaining the structural integrity of epithelial tissue and homeostasis. Its carcinogenesis remains subject debate, as its behavior can vary depending on molecular context specific tumor cell model under study. In this study, we explored head neck squamous carcinoma (HNSCC) mechanism underlying function. (2) Methods: We analyzed expression HNSCC patients using The Cancer Genome Atlas (TCGA) database....
The purpose of the present study was to investigate clinical significance preoperative hematological parameters in patients with advanced stomach cancer, and explore who might benefit from adjuvant concurrent chemoradiotherapy (CCRT) compared chemotherapy alone. Among 1032 node-positive cancer had a confirmed diagnosis after complete D2 resection, received alone or CCRT, total 692 selected using propensity score matching. absolute neutrophil count, lymphocyte count (ALC), monocyte (AMC),...
Abstract The notoriously high proliferation rate of cancer cells requires them to constantly deal with the balance adjustment between oxidative stress overload and upregulated protective antioxidant pathways. It puts in a vulnerable state whenever one piece this puzzle went out control. Non-thermal plasma (NTP) is partially ionized gas operated at or around body temperature has emerged as new potential anti-cancer therapy due its ability release induce ROS, RNS, other free radicals well...