A5026945708- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced Radiotherapy Techniques
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiation Therapy and Dosimetry
- Liver Disease Diagnosis and Treatment
- Management of metastatic bone disease
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Hepatitis B Virus Studies
- Lung Cancer Treatments and Mutations
- Liver Disease and Transplantation
- Cancer Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Cancer, Hypoxia, and Metabolism
- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Oral and gingival health research
- Breast Lesions and Carcinomas
- Cancer, Lipids, and Metabolism
- Endoplasmic Reticulum Stress and Disease
- Lung Cancer Research Studies
- Breast Cancer Treatment Studies
- Infrared Thermography in Medicine
- Multiple and Secondary Primary Cancers
Soonchunhyang University
2015-2024
Bucheon University
2016-2023
Samsung Medical Center
2010-2018
Korea University
2016
Kyung Hee University Hospital at Gangdong
2013-2014
Kyung Hee University
2013
Korea Institute of Radiological and Medical Sciences
2012-2013
Sungkyunkwan University
2010-2012
Marmara University
2010
Keimyung University
2006
The objective of this study was to evaluate the efficacy and safety stereotactic body radiation therapy (SBRT) as a local salvage treatment after incomplete transarterial chemoembolization (TACE) for inoperable hepatocellular carcinoma (HCC).The main eligibility criteria were greatest tumor dimension (LD sum) <10 cm, HCC, response TACE. Prescribed SBRT doses up 60 gray (Gy) in 3 fractions, but reduced until normal tissue constraints allowed.Between May 2008 February 2011, 50 patients...
Abstract Background Recent studies using stereotactic body radiotherapy (SBRT) for hepatocellular carcinoma (HCC) have reported high tumor response and local control. However, the optimal SBRT dose remains unknown, it is still not clear whether a relationship control (LC) overall survival (OS) exist or not. We performed this study to determine LC OS observed in inoperable HCC. Methods Between 2003 2011, 108 patients with HCC were treated SBRT. All unsuitable surgery ablation had incomplete...
Background Although several prospective studies have reported the efficacy of stereotactic body radiotherapy (SBRT) for hepatocellular carcinoma (HCC), treatment‐related toxicity varies and has not been determined. Therefore, authors evaluated safety SBRT patients with HCC in a hepatitis B virus‐endemic area. Methods This multicenter phase 2 trial enrolled unresectable HCC. Patients received 45 to 60 Gy 3 fractions. To evaluate gastroduodenal toxicity, esophagogastroduodenoscopy (EGD) was...
Abstract Background and Objectives This study evaluated the treatment result of high dose stereotactic body radiation therapy (SBRT) for colorectal oligometastases. Methods Between 2003 2009, 41 patients with 50 lesions confined to one organ from cancer (CRC) treated SBRT ≥45 Gy were retrospectively reviewed. Lymph nodes (LNs) (18 patients) most frequent sites followed in order by lung (12) liver (11). doses ranged 45 60 three fractions (median 48 Gy). The cumulative gross tumor volume (GTV)...
The purpose of this study was to assess the feasibility and efficacy stereotactic ablative radiotherapy (SABR) for liver tumor in patients with Barcelona Clinic Liver Cancer (BCLC)-C stage hepatocellular carcinoma (HCC). We retrospectively reviewed medical records 35 between 2003 2011. Vascular invasion diagnosed 32 patients, extrahepatic metastases 11 both 8. Thirty-two were categorized under Child-Pugh (CP) class A 3 CP B. median SABR dose 45 Gy (range, 30-60 Gy) 3-5 fractions. survival...
To evaluate the palliative role of radiotherapy (RT) and define effectiveness chemotherapy combined with RT (CCRT) in patients a symptomatic pelvic mass metastatic colorectal cancer.From August 1995 to December 2007, 80 cancer were treated at Samsung Medical Center. Initial presenting symptoms pain (68 cases), bleeding (18 obstruction (nine cases). The originated from rectal 58 (73%) colon 22 (27%). Initially 72 (90%) surgery, including 64 complete local excisions; 77% 81% cancer. total dose...
To evaluate and compare the risks of secondary cancers from therapeutic doses received by patients with hepatocellular carcinoma (HCC) during intensity-modulated radiotherapy (IMRT), volumetric arc therapy (VMAT), tomotherapy (TOMO).Treatments for five were planned using IMRT, VMAT, TOMO. Based on Biological Effects Ionizing Radiation VII method, excess relative risk (ERR), absolute (EAR), lifetime attributable (LAR) evaluated doses, which measured radiophotoluminescence glass dosimeters...
Purpose There is limited data on radiotherapy (RT) for hepatocellular carcinoma (HCC) in patients with Child-Pugh classification B (CP-B). This study aimed to evaluate the treatment outcomes of fractionated conformal RT HCC CP-B. Materials and Methods We retrospectively reviewed CP-B treated between 2009 2014 at 13 institutions Korea. was diagnosed by Korea guideline 2009, modern techniques were applied. Fraction size ≤ 5 Gy biologically effective dose (BED) ≥ 40 Gy10 (α/β = 10 Gy). A total...
To determine the effectiveness of salvage radiation therapy (RT) in patients with loco-regional recurrences (LRR) following initial complete resection non-small cell lung cancer (NSCLC) and assess prognostic factors affecting survivals.Between 1994 2007, 64 LRR after surgery NSCLC were treated high dose RT alone (78.1%) or concurrent chemo-radiation (CCRT, 21.9%) at Samsung Medical Center. Twenty-nine (45.3%) had local recurrence, 26 (40.6%) regional recurrence 9 (14.1%) both components. The...
This study sought to evaluate the differential effects of bladder distention on point A-based (AICBT) and three-dimensional conformal intracavitary brachytherapy (3D-ICBT) planning for cervical cancer. Two sets CT scans were obtained ten patients effect distention. After first scan, with an empty bladder, a second set was filled. The clinical target volume (CTV), rectum, small bowel delineated each image set. AICBT 3D-ICBT plans generated, we compared different techniques respect dose...
The purpose of this study is to investigate the current status stereotactic body radiotherapy (SBRT) in Korea. A nationwide survey was conducted by Korean Stereotactic Radiosurgery Group Society for Radiation Oncology (KROG 13-13). SBRT defined as with delivery a high dose radiation an extracranial lesion ≤ 4 fractions. 16-questionnaire sent e-mail chief oncology at 85 institutions June 2013. All (100%) responded survey. Of these, 38 (45%) have used and 47 (55%) not SBRT. Regarding treatment...
This study evaluated the incidence of hepatic toxicity after stereotactic ablative radiotherapy (SABR) using 3 fractions to liver, and identified predictors for toxicity. We retrospectively reviewed 78 patients with primary metastatic liver cancers, who underwent SABR between 2003 2011. To examine toxicity, we defined newly developed toxicity≥grade 2 according National Cancer Institute Common Terminology Criteria Adverse Events v4.0 within months end as a significant adverse event. identify...
To determine the optimal radiotherapy technique for gastric mucosa-associated lymphoid tissue lymphoma (MALToma), we compared dosimetric parameters and risk of solid secondary cancer from scattered doses among anterior-posterior/posterior-anterior parallel-opposed fields (AP/PA), anterior, posterior, right, left lateral (4_field), 3-dimensional conformal (3D-CRT) using noncoplanar beams, intensity-modulated composed 7 coplanar beams (IMRT_co) (IMRT_non).We retrospectively generated 5...
This study evaluated the treatment results and necessity to irradiate supraclavicular lymph node (SCN) region in pathological N0-N1 (pN0-N1) patients with locally advanced breast cancer treated neoadjuvant chemotherapy (NAC) followed by surgery radiotherapy (RT).Between 1996 2008, 184 initial tumor size >5 cm or clinically positive nodes were NAC RT. Among these patients, we retrospectively reviewed 98 pN0-N1. Mastectomy was performed 55%. The stage N0 49% N1 51%. All received adjuvant RT...
To investigate practical patterns for stereotactic body radiotherapy to hepatocellular carcinoma in Korea. In June 2013, the Korean Stereotactic Radiosurgery Group of Society Radiation Oncology conducted a national patterns-of-care survey about liver lesion carcinoma, consisting 19 questions and 2 clinical scenarios. All 208 radiation oncologists (100%), who are regular members Oncology, responded this survey. Among these, 95 were specialists hepatology; 64 physicians did not use 31 used...
The purpose of this study was to analyze the rotational errors roll, pitch, and yaw in whole breast cancer treated by three-dimensional radiation therapy (3D-CRT) using TomoDirect (TD). Twenty-patient previously with TD 3D-CRT selected. We performed a retrospective clinical analysis based on 80 images megavoltage computed tomography (MVCT) including systematic random variation patient setup treatment margin (mm). In addition, error (degree) for each analyzed automatic image registration. X,...
We propose a novel pinhole collimator in which the shape can be changed real-time, and new single-photon emission computed tomography (SPECT) system that utilizes this variable (VP) collimator. The acceptance angle distance between object of VP SPECT are varied so optimum value region-of-interest (ROI) obtained for each rotation angle. Because these geometrical variations, correction methods required image reconstruction. In study, we developed two methods. first is sensitivity-correction...
The Korean Radiation Oncology Group (12-02) investigated the outcome of stereotactic ablative radiotherapy for hepatocellular carcinoma ≤5 cm using 60 Gy in three fractions. To evaluate dosimetric differences and compliance a multicenter trial, planning dummy run procedure was performed. All six participating institutions were provided contours two cases. Plans performed following study protocol to cover target volume with minimum 90% prescription dose satisfy constraints organs at risk. We...