A5033393803- Nitric Oxide and Endothelin Effects
- Molecular Sensors and Ion Detection
- Sulfur Compounds in Biology
- Neonatal Health and Biochemistry
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Heme Oxygenase-1 and Carbon Monoxide
- Infant Nutrition and Health
- Cannabis and Cannabinoid Research
- Neonatal and Maternal Infections
- Remote Sensing and Land Use
- Acute Kidney Injury Research
- Pediatric Hepatobiliary Diseases and Treatments
- Remote-Sensing Image Classification
- Organ Transplantation Techniques and Outcomes
- Environmental Changes in China
- Cytomegalovirus and herpesvirus research
Guangzhou Medical University
2022-2024
University of Jinan
2017-2019
Beijing Forestry University
2011
We have previously reported on the potential pathogenic role of neutrophils in biliary atresia (BA). Herein, we aimed to delineate CD177+ pathogenesis BA.Immune cells from livers mice with rhesus rotavirus-induced BA were analysed. Single-cell RNA-sequencing was performed specifically analyse Gr-1+ (Ly6C/Ly6G+) liver. Gene expression profiles analysed using Smart-Seq method, and examined Cd177-/- mice. Neutrophil extracellular trap (NET) inhibitors used determine cell-derived NETs...
A simple highly specific and sensitive ratiometric fluorescent probe has been constructed to monitor carbon monoxide levels in living cells.
A simple colorimetric and far-red fluorescent probe was developed for the first time to visualize gasotransmitter carbon monoxide in subcellular mitochondria.
Our previous study indicated that CD177+ neutrophil activation has a vital role in the pathogenesis of biliary atresia (BA), which is partially ameliorated by N-acetylcysteine (NAC) treatment. Here, we evaluated clinical efficacy NAC treatment and profiled liver-resident immune cells via single cell RNA-sequencing (scRNA-seq) analysis to provide comprehensive landscape NAC-derived regulation.A pilot was conducted evaluate potential effects intravenous on infants with BA, 3-month follow-up...
Highlights•CD14 facilitates perinatal HCMV infection in biliary epithelial cells (BECs) via CD55.•PARP-1-mediated cell death was detected CMV-infected BECs.•CD14 knockout delays the onset of illness and reduces MCMV-induced bile duct damage mice.•Administration anti-mouse CD14 antibody PARP-1 inhibitor treatment MCMV-infected mice resulted amelioration reduced mortality.AbstractBackground & AimsA high human cytomegalovirus (HCMV) rate accompanied by an increased level is observed period. The...
Based on the important role of hypochlorous acid (HOCl) in immune system and numerous physiological processes, detection intracellular basal HOCl is significant interest. In this work, we present a simple thiocarbamate-protected fluorescein fluorescent probe, TCFL, for imaging live cells. Surprisingly, probe TCFL could determine quantitatively large concentration range with limit 0.65 nM. addition, showed excellent specificity presence other higher analytes (1 mM). Moreover, exhibited rapid...
In order to rapidly and accurately extract the feature information of sandy area in north Yanchi County, QuickBird high-resolution remote sensing images were selected as data source. The choice best segmentation scale was analysed depth. way object-oriented supervised classification by rules used into extraction. results show image can quickly characteristic County choosing appropriate which is determined different characteristics extraction information.