A5107411122- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Cervical Cancer and HPV Research
- Gastric Cancer Management and Outcomes
- COVID-19 and healthcare impacts
- Viral-associated cancers and disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Clinical practice guidelines implementation
- Bariatric Surgery and Outcomes
- Inflammatory Bowel Disease
- Vascular Malformations and Hemangiomas
- Stoma care and complications
- Lymphatic Disorders and Treatments
- Anorectal Disease Treatments and Outcomes
- Gastrointestinal disorders and treatments
- Pelvic floor disorders treatments
- Abdominal Surgery and Complications
- Surgical site infection prevention
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Treatments and Studies
- Neuroendocrine Tumor Research Advances
- Healthcare Quality and Management
- Dental Education, Practice, Research
Cumbria Northumberland Tyne and Wear NHS Foundation Trust
2025
Chelsea and Westminster Hospital NHS Foundation Trust
2016-2024
Chelsea and Westminster Hospital
2010-2024
Imperial College London
2005-2024
St Mark's Hospital
2004-2005
Royal Hospital for Children
1986
A comparison between NCCN, ESMO and JSCCR Guidelines is presented, concerning the treatment of rectal cancer, with an analysis discussion their discrepancies. Differences indicate areas for research.Overall survival from cancer has almost doubled over last 20 years. Following recommendations in management guidelines plays some part this, but extent discrepancies them not been evaluated.National Comprehensive Cancer Network (NCCN, USA), European Society Medical Oncology (ESMO, Europe)...
In the UK, endoscopy certification is awarded when trainees attain minimum competency standards for independent practice. A national evidence-based review was undertaken to update and develop recommendations colonoscopy training certification.Under oversight of Joint Advisory Group (JAG), a modified Delphi process conducted between 2019 2020 with multisociety expert representation. Following literature Grading Recommendations, Assessment, Development Evaluations appraisal, recommendation...
Abstract Adipose tissue is reported to contain monocyte-like pre-adipocytes, which may mature into macrophages, contributing local inflammation. Dendritic cells (DC) can be derived from monocytes and initiate regulate primary immune responses. We hypothesized, therefore, that adipose provide DC involved in activity. To test this, we studied human omental samples 17 patients with benign gynecological disease. The hypothesis are inflammatory disease was tested by comparing these those 18...
significant impact on the delivery of colorectal cancer (CRC) care, among other surgical services, due to need
Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the gold standard procedure for ulcerative colitis refractory to medical treatment, as an alternative permanent end ileostomy. Gaining experience in pouch surgery difficult performed infrequently. This study presents institutional initiative promote standardisation of multidisciplinary care IPAA surgery.A dedicated pathway patients who had or are considering was developed among colorectal surgeons, gastroenterologists,...
The incidences of anogenital HPV-related cancers in women are on the rise; this is especially true for anal cancer. Medical societies now beginning to recommend cancer screening certain high-risk populations, including with a history genital dysplasia. aim study investigate national HPV trends as well role demographics, deprivation, and ethnicity incidence England, an attempt better understand cohort which increasingly affected by disease. Demographic data from Clinical Outcomes Services...
Abstract Complications of ileoanal pouch surgery affecting function and quality life may require surgical correction or excision. The management patients with dysfunction requires a multidisciplinary approach demand for service provision include multiple healthcare professionals resources. aim this study is to present the requirements, outcomes redo excision, cost analysis required All undergoing revision excision from June 2021 May 2023 were prospectively included. Patient only diagnostic...
Background: Colorectal Cancer (CRC) is a disease of the elderly, and with an ageing population, oncological surgical procedures for CRC in elderly expected to increase. However, balance between benefits risks associated age comorbidities patients obscure.Materials methods: A retrospective database consecutive who received surgery was used compare short-term outcomes aged ≥75 <75 years old undergoing resection.Results: There were 54 (63.5%) group 31 (36.5%) group. Overall, there no...
Improved survival of children with acute lymphoblastic leukaemia who relapse during therapy has been reported using the Capizzi maintenance regimen. We have treated ten such patients, without histocompatible donors, this regimen, which consisted fortnightly doses vincristine (1.5 mg/m2) and an escalating dose intravenous methotrexate (90-470 followed 24 hours later by asparaginase (15,000 units). Remission disease had successfully achieved in all patients conventional prior to start...