Nicholas I. Church

ORCID: 0000-0001-6848-1929
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About
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Research Areas
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Gastrointestinal disorders and treatments
  • Esophageal and GI Pathology
  • IgG4-Related and Inflammatory Diseases
  • Pancreatitis Pathology and Treatment
  • Gastrointestinal Tumor Research and Treatment
  • Pancreatic and Hepatic Oncology Research
  • Gallbladder and Bile Duct Disorders
  • Helicobacter pylori-related gastroenterology studies
  • Colorectal Cancer Screening and Detection
  • Hemostasis and retained surgical items
  • Colorectal Cancer Surgical Treatments
  • Neuroendocrine Tumor Research Advances
  • Liver Disease and Transplantation
  • Diverticular Disease and Complications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Organ Transplantation Techniques and Outcomes
  • Biliary and Gastrointestinal Fistulas
  • Acute Ischemic Stroke Management
  • Anesthesia and Sedative Agents
  • Blood transfusion and management
  • Blood donation and transfusion practices
  • Gastric Cancer Management and Outcomes
  • Lung Cancer Diagnosis and Treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies

NHS Lothian
2023

Vatican Secret Archives
2021

Grammar School
2021

Edinburgh Royal Infirmary
2010-2020

University of Leicester
2017

George Institute for Global Health
2017

Peking University
2017

Clínica Alemana
2017

Universidad del Desarrollo
2017

Fukuoka University
2017

OBJECTIVE Most cases of autoimmune pancreatitis (AIP) have been reported from Japan. We present data on a UK series, including clinical and radiological features at presentation, longitudinal response to immunosuppression. METHODS Over an 18-month period, all patients diagnosed in our center with AIP were studied. Endoscopic biliary stenting was performed as required, treated prednisolone, assessed longitudinally. In disease relapse following steroid reduction, azathioprine instituted....

10.1111/j.1572-0241.2007.01531.x article EN The American Journal of Gastroenterology 2007-09-25

<h3>Background</h3> Characteristic pancreatic duct changes on endoscopic retrograde pancreatography (ERP) have been described in autoimmune pancreatitis (AIP). The performance characteristics of ERP to diagnose AIP were determined. <h3>Methods</h3> study was done two phases. In phase I, 21 physicians from four centres Asia, Europe and the USA, unaware clinical data or diagnoses, reviewed 40 preselected ERPs patients with (n=20), chronic (n=10) cancer (n=10). Physicians noted presence absence...

10.1136/gut.2010.207951 article EN Gut 2010-12-03

In the UK, endoscopy certification is awarded when trainees attain minimum competency standards for independent practice. A national evidence-based review was undertaken to update and develop recommendations colonoscopy training certification.Under oversight of Joint Advisory Group (JAG), a modified Delphi process conducted between 2019 2020 with multisociety expert representation. Following literature Grading Recommendations, Assessment, Development Evaluations appraisal, recommendation...

10.1136/flgastro-2022-102260 article EN cc-by-nc Frontline Gastroenterology 2023-01-27

Acute upper gastrointestinal bleeding (AUGIB) is the commonest reason for hospitalization with hemorrhage in UK and leading indication transfusion of red blood cells (RBCs). Observational studies suggest an association between more liberal RBC adverse patient outcomes, a recent randomised trial reported increased further mortality policy. TRIGGER (Transfusion Gastrointestinal Bleeding) pragmatic, cluster randomized which aims to evaluate feasibility safety implementing restrictive versus...

10.1016/j.tmrv.2013.04.001 article EN cc-by Transfusion Medicine Reviews 2013-05-22

To compare colonoscopy quality with nitrous oxide gas (Entonox

10.4253/wjge.v9.i9.471 article EN cc-by-nc World Journal of Gastrointestinal Endoscopy 2017-01-01

Summary Background Upper gastrointestinal bleeding (UGIB) remains a common cause of presentation and admission to hospital in the UK, with incidence Scotland one highest world. Aims To investigate difference demographics, deprivation quintiles, aetiology clinical outcomes patients presenting UGIB hospitals across over 16‐year period Methods Data were collected using National Catalogue analysed retrospectively Safe Haven. Results We included 129 404 patients. The annual number remained...

10.1111/apt.16170 article EN Alimentary Pharmacology & Therapeutics 2020-11-18

Endoscopic therapy improves the outcome of nonvariceal upper gastrointestinal hemorrhage. Routine second-look procedures may not improve outcome. Patients who rebleed after endoscopic for ulcer hemorrhage should be treated by further therapy, rather than urgent surgery. Thinner endoscopes offer adequate visualization with improved patient tolerance, and new therapeutic methods continue to evaluated. Stigmata recent their interpretation remain a topic discussion. The Rockall scoring system is...

10.1097/00001574-199911000-00008 article EN Current Opinion in Gastroenterology 1999-11-01

Introduction Joint Advisory Group (JAG) certification in endoscopy is awarded when trainees attain minimum competency standards for independent practice. A national evidence-based review was undertaken to update training and flexible sigmoidoscopy (FS). Methods modified Delphi process conducted between 2019 2020 with multisociety representation from experts trainees. Following literature Grading of Recommendations, Assessment, Development Evaluations appraisal, recommendation statements on...

10.1136/flgastro-2022-102259 article EN cc-by-nc Frontline Gastroenterology 2023-01-27

<h3>Introduction</h3> The British Society of Gastroenterology guidelines on the management suspected acute upper gastrointestinal bleeding (AUGIB) recommend that endoscopy (OGD) is performed within 24 hours presentation. However, certain hospital sites in UK have no provision for therapeutic and optimal AUGIB scoring system inter-hospital transfers has not been determined. In our trust, patients at a district general (DGH) are transferred to tertiary care (Royal Infirmary Edinburgh, RIE) if...

10.1136/gutjnl-2023-bsg.309 article EN Poster presentations 2023-06-01

10.1016/j.mpmed.2016.11.004 article EN Medicine 2017-01-10

TO THE EDITOR: We would like to thank Matsushita et al. for their interest in our article. They raise specific points concerning the type of steroid therapy acute autoimmune pancreatitis (AIP) and use azathioprine disease relapse. These are part broader question: What is optimum (AIP)? This question remains unanswered, as published data include only small case series reports. No randomized controlled exist.

10.1111/j.1572-0241.2008.01959_2.x article EN The American Journal of Gastroenterology 2008-07-01

10.1016/s0016-5107(16)30687-3 article Gastrointestinal Endoscopy 2016-11-14

Upper gastrointestinal (UGI) haemorrhage is common and carries a significant mortality. Peptic ulcer disease remains the most aetiology but varices are an important cause. The patient's history, physiology blood results guide timing of endoscopy may disclose underlying liver disease. Resuscitation risk assessment with Blatchford Rockall scores main priorities in acute presentation. Haemodynamically unstable patients, patients suspected bleeding should have urgent immediately after...

10.1016/j.mpmed.2012.11.003 article EN Medicine 2013-02-01
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