A5031375305- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Invertebrate Immune Response Mechanisms
- Immune Cell Function and Interaction
- Reproductive biology and impacts on aquatic species
- Physiological and biochemical adaptations
- Metal complexes synthesis and properties
- Immune Response and Inflammation
- Gender, Labor, and Family Dynamics
- Labor market dynamics and wage inequality
- T-cell and B-cell Immunology
- Monetary Policy and Economic Impact
- Crystal structures of chemical compounds
- Aldose Reductase and Taurine
- Gut microbiota and health
- Global Financial Crisis and Policies
- Complex Systems and Time Series Analysis
- Pharmacological Effects of Natural Compounds
- interferon and immune responses
- Antimicrobial Peptides and Activities
- Metal-Organic Frameworks: Synthesis and Applications
- Adipose Tissue and Metabolism
- Market Dynamics and Volatility
- Cancer Immunotherapy and Biomarkers
- Animal Genetics and Reproduction
Zhengzhou University
2024-2025
Huazhong Agricultural University
2016-2024
Northeastern University
2024
Ministry of Education of the People's Republic of China
2023
Ministry of Agriculture and Rural Affairs
2022-2023
First Institute of Oceanography
2023
Ministry of Natural Resources
2023
Zhejiang Institute of Freshwater Fisheries
2016-2021
Ocean University of China
2010-2019
University of London
2015-2019
Fishmeal could only be replaced by plant proteins at limited levels in aquafeeds, especially for carnivorous fish. In this study, an experiment was designed to evaluate the possibility of improving utilization maggot meal supplementation turbot diet. Five diets were formulated: a reference diet (FM) containing 63% fishmeal and four experimental (35(0%), 35(3%), 40(0%), 40(3%)) which substituted different with 0–3% meal. Turbot (4.90 ± 0.03 g) fed these 9 weeks. successfully without growth...
The fish intestinal mucosa is among the main sites through which environmental microorganisms interact with host. Therefore, this tissue not only constitutes first line of defense against pathogenic but also plays a crucial role in commensal colonization. interaction between mucosal immune system, microbiota, and viral pathogens has been extensively described mammalian intestine. However, very few studies have characterized these interactions early vertebrates such as teleosts. In study,...
Poliovirus receptor (PVR) and its system, including TIGIT, CD226, CD96, play a pivotal role in orchestrating tumor immune evasion. Upon engagement with PVR on cells, CD96 exerts inhibitory effects the function of T cells NK thereby fostering Therefore, screening checkpoint inhibitors (ICIs) targeting CD96/PVR pathway will provide promising candidates for immunotherapy. In this investigation, we employed MOE software to conduct virtual small molecules from FDA-approved drug library. Our...
Elevated environmental ammonia leads to respiratory disorders and metabolic dysfunction in most fish species, the majority of research has concentrated on behavior gill function. Prior studies have rarely shown molecular mechanism largemouth bass hepatic response loading. In this experiment, 120 were exposed total nitrogen 0 mg/L or 13 for 3 7 days, respectively. Histological study indicated that exposure severely damaged liver structure, accompanied by increased serum alanine...
The objective of the study was to evaluate effects incorporating plant protein blend in juvenile turbot (Scophthalmus maximus L.) diet on free amino acid (AA) concentration and expression genes related peptide AA transporters, key enzymes metabolism response (AAR) pathway. Fish were fed diets with fish meal (FM), or 400 g/kg FM replacement by for 9 weeks. Compared diet, PP40 did not affect plasma essential (EAA) metabolic gene intestine, while it significantly upregulated all detected...
Physiological primary teeth exfoliation is a normal phenomenon during development. However, retained can often be observed in the patients with cleidocranial dysplasia (CCD) caused by mutation of Runx2. The potential regulative mechanism still unknown. In present study, periodontal ligament stem cells (PDLSCs) were derived from different resorbed stages and permanent CCD patient. proliferative, osteogenic osteoclast-inductive capacities PDLSCs each group detected. We demonstrated here that...
The digestive tract is a unique series of organs that it inhabited by range commensal microbes, while also exposed to an overwhelming load dietary antigens. It widely known mammals have evolved complex and efficient immune strategies protect the mucosa tract. However, in early vertebrates, roles mucosal defense microbial communities different segments are not well understood. Here, we constructed bath infection model with infectious hematopoietic necrosis virus (IHNV) rainbow trout...
Abstract High dietary protein inclusion is necessary in fish feeds and also represents a major cost the aquaculture industry, which demands improved conversion into body proteins fish. In mammals, target of rapamycin (TOR) key nutritionally responsive molecule governing postprandial anabolism. However, its physiological significance teleosts has not been fully examined. present study, we examined nutritional physiology turbot after chronic inhibition. Our results showed that 6-week...
The olfactory organs (OOs) of vertebrates play important roles in their extraordinary chemosensory capacity, a process during which they are continuously exposed to environmental pathogens. Nasopharynx-associated lymphoid tissue (NALT) contains B cells and immunoglobulins (Igs), function as the first defense line against antigens mammals also exist teleosts. However, immune responses teleost NALT Igs bacterial infection remain largely uncharacterized. In this study, rainbow trout were...