Sex hormone concentrations of eumenorrheic women typically fluctuate across the menstrual cycle and can affect neural function such that estrogen has neuroexcitatory effects, progesterone induces inhibition. However, effects these changes on corticospinal intracortical circuitry motor performance knee extensors are unknown. The present two-part investigation aimed to 1) determine measurement error an exercise task, transcranial magnetic stimulation (TMS)-, nerve (MNS)-derived responses in...

Aim: Previous research into the etiology of neuromuscular fatigue following competitive soccer match-play has primarily focused on peripheral perturbations, with limited assessing central nervous system function in days post-match. The aim present study was to examine and time-course recovery match-play. Methods: Sixteen male semi-professional players completed a 90-min match. Pre-, post- at 24, 48 72 h participants battery neuromuscular, physical perceptual tests. Maximal voluntary...

Females demonstrate greater fatigue resistance than males during contractions at intensities relative to maximum force. However, previous studies have not accounted for the influence of metabolic thresholds on fatigability. This study is first test whether sex differences in fatigability exist when exercise intensity normalised a threshold: critical derived from assessment intensity-duration relationship intermittent, isometric knee extensor contractions. We show that females occurred higher...

Training methods that require maximal intensity efforts against light and heavy resistance are commonly used for athletic development. Typically, these sessions separated by at least 48 h recovery on the assumption such elicit marked fatigue of central nervous system (CNS), but this posit has not been well studied. The aim study was to assess etiology after heavy-resistance (strength), jump, sprint training methods.Ten male athletes completed three requiring varied in their loading...

The response of spinal motoneurons to synaptic input greatly depends on the activation persistent inward currents (PICs), which in turn are enhanced by neuromodulators serotonin and noradrenaline. Local vibration (LV) induces excitatory Ia onto may alter neuromodulatory inputs. Therefore, we investigated whether LV influences contribution PICs motoneuron firing. This was assessed voluntary contractions with concurrent, ongoing LV, as well after a bout prolonged LV. High-density surface...

New Findings What is the central question of study? Are corticospinal responses to acute and short-term squat resistance training task-specific? main finding its importance? A single bout increased spinal excitability, but no changes in were noted following 4 weeks despite task-specific increases strength. The present data suggest that processes along pathway knee extensors play a limited role increase strength training. Abstract Neural adaptations subserving have been shown be...

Performance fatigability is substantially greater when exercising in the severe- versus heavy-intensity domain. However, relevance of boundary between moderate- and exercise, gas exchange threshold (GET), to performance unclear. This study compared alterations neuromuscular function during work-matched exercise above below GET.Seventeen male participants completed cycling for 90, 110, 140 min at 110%, 90%, 70% GET, respectively. Knee extensor isometric maximal voluntary contraction (MVC),...

Women have been shown to experience less neuromuscular fatigue than men in knee extensors (KE) and peripheral plantar flexors (PF) after ultratrail running, but it is unknown if these differences exist for shorter trail running races whether this may impact economy. The purpose of study was characterize sex fatigability over a range distances examine possible the postrace alteration cost (Cr).Eighteen pairs women were matched by performance completing different ranging from 40 171 km,...

New Findings What is the central question of this study ? In order to discern information about testing modalities when assessing neuroplastic responses squat resistance training, present investigated whether corticospinal and intracortical function was different between a joint‐angle‐matched isometric knee extension. main finding its importance The data show poor agreement reinforce notion that task specificity utmost for neuroplasticity. Abstract It has been suggested task‐specific changes...

The physiological mechanisms determining the progressive decline in maximal muscle torque production capacity during isometric contractions to task failure are known depend on demands. Task-specificity of associated adjustments motor unit discharge rate (MUDR), however, remains unclear. This study examined MUDR different submaximal knee extension tasks failure. Participants performed a sustained and an intermittent at 20% 50% voluntary (MVT), respectively (Experiment 1). High-density surface...

Running and cycling represent two of the most common forms endurance exercise. However, a direct comparison neuromuscular consequences these modalities after prolonged exercise has never been made. The aim this study was to compare alterations in function induced by matched-intensity duration running exercise.During separate visits, 17 endurance-trained male participants performed 3 h at 105% gas exchange threshold. Neuromuscular assessments were taken are preexercise, midexercise,...

Electrical stimulation over the mastoids or thoracic spinous processes has been used to assess subcortical contribution corticospinal excitability, but responses are difficult evoke in resting lower limbs limited only a few muscle groups. This might be mitigated by delivering stimuli on spinal column, where descending tracts contain greater relative density of motoneurons projecting limb muscles. We investigated activation axons innervating tibialis anterior (TA) and rectus femoris (RF)...

Aim: Cryotherapy is commonly implemented following soccer match-play in an attempt to accelerate the natural time-course of recovery, but effect this intervention on neuromuscular function unknown. The aim present study was examine donning lower-body garments fitted with cooled phase change material (PCM) recovery competitive match-play. Methods: Using a randomised, crossover design, 11 male semi-professional players wore PCM 15ºC (PCMcold) or left at ambient temperature (PCMamb; sham...

Cancer-related fatigue (CRF) is a debilitating symptom that affects around one-third of people for months or years after cancer treatment. In recent study, we found with posttreatment CRF have greater neuromuscular fatigability. The aim this secondary analysis was to examine the etiology fatigability in CRF.Ninety-six who had completed treatment were dichotomized into two groups (fatigued and nonfatigued) based on clinical cut point fatigue. Alterations function (maximal voluntary...

The aim of this study was to assess differences in motor performance, as well corticospinal and spinal responses transcranial magnetic percutaneous nerve stimulation, respectively, during submaximal isometric, shortening, lengthening contractions between younger older adults. Fifteen [26 yr (SD 4); 7 women, 8 men] 14 [64 3); 5 9 adults performed isometric shortening dorsiflexion on an isokinetic dynamometer (5°/s) at 25% 50% contraction type-specific maximums. Motor evoked potentials (MEPs)...

The purpose of this experiment was to assess performance during repeated sprints utilizing self-selected recovery intervals in youth football (soccer) players at different stages maturation.Quota sampling method used recruit 14 prepeak height velocity (PHV) and post-PHV participants for the study (N = 28; age 13 [0.9] y, stature 162.5 [10.8] cm, mass 50.2 [12.7] kg). Players performed comprising 10 × 30 m efforts under 2 experimental conditions: using 30-second intervals. Magnitude effects...

Cervicomedullary stimulation provides a means of assessing motoneuron excitability. Previous studies demonstrated that during low-intensity sustained contractions, small cervicomedullary evoked potentials (CMEPs) conditioned using transcranial magnetic (TMS-CMEPs) are reduced, whereas large TMS-CMEPs less affected. As recruit motoneurons most active contractions high proportion inactive the task, these results suggest reductions in excitability could be dependent on repetitive activation. To...

The purpose of this study was to assess corticospinal excitability soleus (SOL) and tibialis anterior (TA) at a segmental level during passive ankle movement. Four experimental components were performed the effects movement muscle length on (MEP/Mmax) different lengths, subcortical lumbar spinal segments (LEP/Mmax), intracortical inhibition (SICI) facilitation (ICF), H-reflex in SOL TA. In addition, degree fascicle changes between TA assessed subpopulation Fascicles shortened lengthened with...

Abstract Background The Rating of Fatigue (ROF) scale can measure changes in perceived fatigue a variety contexts. Objective aim the present study was to translate and subsequently validate ROF French language. Methods composed three phases. Phase 1 involved comprehensive translation, back-translation, consolidation process order produce scale. During phase 2, face validity assessed. A cohort 60 native speaking participants responded range Likert items which probed purposes what it is...

Central nervous system excitability depends on the task performed, muscle group solicited, and contraction type. However, little is known corticospinal motoneuronal measured during locomotor exercise. This study aimed at determining reliability of motor-evoked potentials (MEP) thoracic (TMEP) in dynamic mode unfatiguing fatiguing cycling