- Muscle activation and electromyography studies
- Transcranial Magnetic Stimulation Studies
- Sports Performance and Training
- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Sports injuries and prevention
- Motor Control and Adaptation
- Sport Psychology and Performance
- Cardiac Arrest and Resuscitation
- Neural and Behavioral Psychology Studies
- Pain Management and Treatment
- Cardiac Ischemia and Reperfusion
- EEG and Brain-Computer Interfaces
- Genomic variations and chromosomal abnormalities
- Genetics and Neurodevelopmental Disorders
- Exercise and Physiological Responses
- Muscle metabolism and nutrition
- Cardiovascular Effects of Exercise
- Occupational Health and Performance
- Growth Hormone and Insulin-like Growth Factors
- Thermoregulation and physiological responses
- Spinal Cord Injury Research
- Coffee research and impacts
- Cardiovascular Syncope and Autonomic Disorders
- Non-Invasive Vital Sign Monitoring
Northumbria University
2019-2025
Medway School of Pharmacy
2015-2022
University of Kent
2015-2022
University of Cagliari
1994-2014
Transcranial direct current stimulation (tDCS) can increase cortical excitability of a targeted brain area, which may affect endurance exercise performance. However, optimal electrode placement for tDCS remains unclear. We tested the effect two different montages improving Nine subjects underwent control (CON), placebo (SHAM) and montage sessions in randomized design. In one session, anodal was placed over left motor cortex cathodal on contralateral forehead (HEAD), while other above...
BackgroundTranscranial direct current stimulation (tDCS) has been used to enhance endurance performance but its precise mechanisms and effects remain unknown.ObjectiveTo investigate the effect of bilateral tDCS on neuromuscular function during a cycling time task failure (TTF) test.MethodsTwelve participants in randomized order received placebo (SHAM) or real with two cathodes (CATHODAL) anodes (ANODAL) over motor cortices opposite electrode pair ipsilateral shoulders. Each session lasted 10...
To investigate the effects of caffeine on performance, neuromuscular fatigue and perception effort during high-intensity cycling exercise in moderate hypoxia.Seven adult male participants firstly underwent an incremental test a cycle ergometer conditions acute normobaric hypoxia (fraction inspired oxygen = 0.15) to establish peak power output (PPO). In following two visits, they performed time exhaustion (78 ± 3% PPO) same hypoxic after ingestion (4 mg kg-1) one placebo double-blind,...
The aims of this investigation were to describe the central alterations neuromuscular function induced by exhaustive high-intensity one-leg dynamic exercise (OLDE, study 1) and indirectly quantify feedback from group III-IV muscle afferents via occlusion (MO, 2) in healthy adult male humans. We hypothesized that these their recovery are associated with changes afferent feedback. Both studies consisted two time-to-exhaustion tests at 85% peak power output. In 1, voluntary activation level...
Abstract Purpose Despite their widespread use in exercise physiology, time-to-exhaustion (TTE) tests present an often-overlooked challenge to researchers, which is how computationally deal with between- and within-subject differences duration. We aimed verify the best analysis method overcome this problem. Methods Eleven cyclists performed incremental test three TTE differing workload as preliminary tests. The TTEs were used derive individual power–duration relationship needed set...
New Findings What is the central question of study? Are corticospinal responses to acute and short-term squat resistance training task-specific? main finding its importance? A single bout increased spinal excitability, but no changes in were noted following 4 weeks despite task-specific increases strength. The present data suggest that processes along pathway knee extensors play a limited role increase strength training. Abstract Neural adaptations subserving have been shown be...
A reduction in catecholamine levels during exercise has been described young subjects with type 1 diabetes mellitus (DM1). It suggested that per se is associated the loss of sympathetic response before any clinical evidence. Considering an increase drive required for normal cardiovascular to muscle metaboreflex, aim this study was assess hemodynamics metaboreflex DM1 patients. Impedance cardiography used measure activation, obtained through postexercise ischemia 14 patients and 11 healthy...
This study was devised to measure certain physiological variables related the energy requirement together with a match analysis during real Muay Thai matches. Twenty skilled male fighters were recruited and performed laboratory incremental preliminary test assess their maximum oxygen uptake anaerobic threshold. They then involved in competitions. During matches heart rate (HR) blood lactate (BLa) values collected. Moreover, filmed analysed for subsequent determination of techniques used....
The aim of the present study was to test contribution stroke volume (SV) in hemodynamic response muscle metaboreflex activation healthy individuals. We hypothesized that an acute decrease cardiac afterload and preload due administration a vasodilating agent could reduce postexercise ischemia (PEMI)-induced SV response. Ten males (age 33.6 ± 1.3 yr) were enrolled randomly assigned following protocol: 1) PEMI session, 2) control exercise recovery (CER) 3) after sublingual 5 mg isosorbide...
Exercise capacity remains lower in heart transplant recipients (HTRs) following compared with normal subjects, despite improved cardiac function. Moreover, metaboreceptor activity the muscle has been reported to increase. The aim of present investigation was assess exercise together metaboreflex HTR patients for 1 yr transplant, test hypothesis that recovery paralleled by improvements response metaboreflex. A cardiopulmonary and Vo(2max) hemodynamic activation obtained postexercise ischemia...
Purpose : Professional football players experience both physical and mental fatigue (MF). The main aims of this randomized crossover study were to investigate the effect MF on repeated-sprint ability (RSA) effects psychomotor vigilance. Methods: Seventeen male professional performed 10 maximal 20-m shuttle sprints interspaced by incomplete recovery (RSA test). Running speed, heart rate, brain oxygenation, rating perceived exertion monitored during each sprint. RSA test was preceded either a...
Spinal cord injured (SCI) individuals show an altered hemodynamic response to metaboreflex activation due a reduced capacity vasoconstrict the venous and arterial vessels below level of lesion. Exercise training was found enhance circulating catecholamines improve cardiac preload tone in exercise SCI subjects. Therefore, would result enhanced diastolic function circulation. The aim this study test hypothesis that one year improves these Nine were enrolled underwent at beginning (T0) after...
Exercise intolerance and early fatiguability are hallmark symptoms of chronic heart failure. While the malfunction is certainly leading cause failure, patho-physiological mechanisms exercise in these patients more complex, multifactorial only partially understood. Some evidence points towards a potential role an exaggerated afferent feedback from group III/IV muscle afferents genesis symptoms. Overactivity may with double action: by inducing cardiovascular dysregulation, reducing motor...
Abstract Purpose This study aimed to verify whether the slowing of muscle contraction quickness, typically observed in states fatigue, may worsen force control by decreasing rate with which fluctuations are modulated. Therefore, we investigated relationship between development (RFD), and fluctuations' magnitude (Coefficient variation, CoV) complexity (Approximate Entropy, ApEn; Detrended fluctuation analysis, DFAα). Methods Fourteen participants performed intermittent ballistic isometric...
Abstract Unaccustomed eccentric exercise (EE) is protective against muscle damage following a subsequent bout of similar exercise. One hypothesis suggests the existence an alteration in motor unit (MU) behaviour during second bout, which might contribute to adaptive response. Accordingly, present study investigated MU changes repeated bouts EE. During two where maximal lengthening dorsiflexion (10 repetitions × 10 sets) was performed 3 weeks apart, voluntary isometric torque (MVIC) and...
Abstract Aim Considering that sympathetic activation is induced by exercise, it reasonable to assume hemodynamic adjustments exercise act in opposition those elicited the diving response. However, cardiovascular measurements have never been performed during underwater dynamic apnoea ( DA ), and this hypothesis remains speculative. Methods Data concerning heart rate HR stroke volume SV ) cardiac output CO static SA were collected from 12 elite divers means of an impedance cardiograph adapted...
This study investigated the effect of ischemic preconditioning (IP) on metaboreflex activation following dynamic leg extension exercise in a group healthy participants.Seventeen participants were recruited. IP and SHAM treatments (3 × 5 min cuff occlusion at 220 mmHg or 20 mmHg, respectively) administered randomized order to upper part exercising leg's thigh only. Muscle pain intensity (MP) pressure threshold (PPT) monitored while administrating treatments. After 3 70% maximal workload,...