A5077883371- Advancements in Transdermal Drug Delivery
- Essential Oils and Antimicrobial Activity
- Acne and Rosacea Treatments and Effects
- Nanoparticle-Based Drug Delivery
- Plant-based Medicinal Research
- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Neuroscience and Neuropharmacology Research
- Lipid Membrane Structure and Behavior
- Pharmacological Effects of Natural Compounds
- interferon and immune responses
- Immune Response and Inflammation
- Toxin Mechanisms and Immunotoxins
Fujian University of Traditional Chinese Medicine
2023
Shanghai University of Traditional Chinese Medicine
2017-2019
To enhance the immunogenicity of model subunit vaccine, ovalbumin (OVA) was combined with platycodin (PD), a saponin adjuvant. reduce toxicity PD, OVA, and adjuvant were loaded together into liposomes before being incorporated dissolving microneedle array.OVA- PD-loaded (OVA-PD-Lipos) prepared using film dispersion method. Their uptake behavior, to mouse bone marrow dendritic cells (BMDCs), hemolytic activity rabbit red blood (RBCs) evaluated. The OVA-PD-Lipos array. chemical stability OVA...
Abstract Background The cGAS-STING signaling pathway is an essential section of the natural immune system. In recent years, increasing number studies have shown a strong link between abnormal activation pathway, mediated by nucleic acid receptor cGAS, and development progression autoimmune diseases. Therefore, it important to identify effective compound specifically downregulate this for disease. Methods effect Glabridin (Glab) was investigated in BMDMs Peripheral blood mononuclear cell...
In this study, we show that the percutaneous absorption and brain distribution of tetramethylpyrazine (TMP) is enhanced when combined with borneol (BN) in a microemulsion-based transdermal therapeutic system (ME-TTS). The formulation TMP BN microemulsion (TEM-BN-ME) was optimized skin permeation studies vitro following uniform experimental design. Male Sprague-Dawley rats were used for vivo pharmacokinetic tissue TMP-BN-ME-TTS. TMP-BN-ME-TTS treated had significantly higher (P < 0.05) Cmax...