A5101742514- Drug Solubulity and Delivery Systems
- Synthesis and biological activity
- Analytical Chemistry and Chromatography
- Surfactants and Colloidal Systems
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Click Chemistry and Applications
- Computational Drug Discovery Methods
- Analytical Methods in Pharmaceuticals
- Natural Antidiabetic Agents Studies
- Spine and Intervertebral Disc Pathology
- Essential Oils and Antimicrobial Activity
- Synthesis and Biological Evaluation
- Sulfur-Based Synthesis Techniques
- Lipid Membrane Structure and Behavior
- Protein purification and stability
- Pharmacological Effects of Natural Compounds
- Thermochemical Biomass Conversion Processes
- Phytochemicals and Antioxidant Activities
- Synthesis and Characterization of Heterocyclic Compounds
- Multicomponent Synthesis of Heterocycles
- Nanoparticle-Based Drug Delivery
- Anesthesia and Pain Management
- Advanced Photocatalysis Techniques
- Organic and Inorganic Chemical Reactions
Guru Ghasidas Vishwavidyalaya
2024
Pharmaceutical Biotechnology (Czechia)
2024
Chhattisgarh Swami Vivekanand Technical University
2023
Ayush & Health Sciences University Chhattisgarh
2019-2022
Banaras Hindu University
2022
Institute of Medical Sciences
2022
Institute of Entomology
2018
Carbon nitride-catalyzed photocatalytic strategies for the oxidation of alcohols, reduction nitro compounds, coupling reactions, and synthesis esters, phenols, sulfoxides have been summarized.
Abstract Background High lipophilicity and poor aqueous solubility are the endemic problems of new drug molecules. Sixty to seventy percent these drugs unable solubilize completely in media, or have very low permeability. This hampers their oral absorption further leads bioavailability. Various researches progress overcome limitations. Novel technologies like nano-carrier systems become popular for improving drugs. Main body Lipid-based formulations, among nano systems, taking pace...
Abstract The PPAR‐γ agonist enhances the insulin sensitivity and avoids disorganized hyperglycemic by promoting guided cellular uptake of blood glucose. Therefore, in present work has chosen as target for molecular docking study to design an effective same. By this research effort been made prepare amide urea series 1, 3, 4‐thiadiazole derivatives 4‐substituted‐N‐(5‐(4‐(1‐piperidino)1‐piperidinyl)‐1,3,4‐(2‐thiadiazolyl)benzamide (4a‐f)...
In this study novel derivatives of 1,2,4-triazole pyridine coupled with Schiff base were obtained in altered aromatic aldehyde and 4-((5-(pyridin-3-yl)-4H-1,2,4-triazol-3-ylthio)methyl)benzenamine reactions. Thin layer chromatography melting point determination employed to verify the purity hybrid derivatives. The structures interpreted using methods comprising infrared, nuclear magnetic resonance, mass spectroscopy. vitro anti-microbial properties minimum inhibitory concentration determined...
Andrographis paniculata is a well-known medicinal plant in Southeast Asia, India and China. The contains andrographolide (AN), very important phytochemical used various health problems. However, AN low oral absorption bioavailability of due to the rapid clearance high protein binding capacity.The present study was aimed develop nano-phytovesicular formulation semi-purified extracts from naturally occurring phospholipid (soya phosphatidylcholine) order increase antihyperglycemic activity...
The α-chymotrypsin activity was tested in aqueous media with the presence of novel cationic amine–based gemini surfactant, different spacer chain lengths and head group size, also compared cetyltrimethylammonium bromide (CTAB) cetyltriphenylphosphonium (CTPB) surfactants buffer only. p-nitrophenyl acetate (PNPA) hydrolysis rate monitored surfactant concentration at 30°C. Most these gave higher catalytic as to CTAB CTPB. highest superactivity measured 16-12-16,...
Quantitative structure–activity relationship (QSAR) has been established for 29 molecules of N, N- diphenylureas, reported to inhibit the binding RANTES membranes prepared from Chinese hamster ovary (CHO) cells stably expressing recombinant human CCR5. Partial Least Square Regressions (PLSR) was used generate between biological activity and calculated descriptors. Model with good statistical qualities developed using software VLIFE MDS 3.0. Validation model done bycross validation,...
Abstract In this article, the enzyme kinetic activity of Mucor javanicus lipase (MJL) has investigated via hydrolysis p ‐nitrophenyl acetate (PNPA) in different pH environment, cationic surfactants, and inorganic salts. The influence hydrophilicity been studied presence cetyltrimethylammonium bromide (CTAB), cetyltriphenylphosphonium (CTPB), cetyldimethylethanolammonium (CDMEAB) surfactants. head group dimensions surfactants show noteworthy contributions to enhance catalytic MJL, that is...
ABSTRACT α‐Chymotrypsin (α‐CT) activity was measured in aqueous buffer with the following alkyltriphenylphosphonium bromide surfactants series cetyl, tetradecyl, and dodecyl as a tail length. For sake of comparison mixed micellar investigation on α‐CT, cationic cetyltriphenylphosphonium (CTPB) nonionic surfactant Triton X‐100, Brij‐56, Brij‐35, Tween 20, Igepal Co‐210 have been used. The p ‐nitrophenyl acetate (PNPA) hydrolysis rate determined at concentration both systems by UV–vis...