A5012093966- Plant Pathogens and Resistance
- Powdery Mildew Fungal Diseases
- Cancer-related molecular mechanisms research
- Plant Pathogens and Fungal Diseases
- FOXO transcription factor regulation
- Bacterial Genetics and Biotechnology
- Ovarian cancer diagnosis and treatment
- Circular RNAs in diseases
- Antimicrobial Peptides and Activities
- Plant-Microbe Interactions and Immunity
- Endometrial and Cervical Cancer Treatments
- Epigenetics and DNA Methylation
- Yeasts and Rust Fungi Studies
- Plant Pathogenic Bacteria Studies
- Advanced biosensing and bioanalysis techniques
- Seedling growth and survival studies
- Spaceflight effects on biology
- Kruppel-like factors research
- Endometriosis Research and Treatment
- Ferroptosis and cancer prognosis
- Probiotics and Fermented Foods
- Ubiquitin and proteasome pathways
- Plant Parasitism and Resistance
- Immune cells in cancer
- S100 Proteins and Annexins
Hainan University
2016-2024
Wenzhou Medical University
2018-2023
Zhejiang Taizhou Hospital
2020-2023
Institute of Microbiology
2005-2008
Chinese Academy of Sciences
2005-2008
University of Chinese Academy of Sciences
2008
Microbiology Institute of Shaanxi
2005-2006
The study purpose was to make investigation into the influence of XIST on cervical cancer progression and what's more its potential mechanism.The data sets (lncRNA, miRNA, mRNA) obtained from TCGA were analyzed with "mixOmics" R package. Then, expression XIST, miR-140-5p, ORC1 detected using qRT-PCR western blot in both tissues cell lines (Hela C33A) verify bioinformatics analyses results. CCK-8 assay, 5-ethynyl-2'-deoxyuridine (EdU) assays, cycle assay apoptosis practiced. Besides,...
Abstract Objectives SMAD3 is pivotal in the biology functions of various tumors. This study aiming to relationship among SMAD3, long noncoding RNAs (lncRNAs) OPA‐interacting protein 5 antisense transcript 1 (OIP5‐AS1), and miR‐143‐3p, their effects on cervical cancer. Methods In our research, real‐time polymerase chain reaction western blot assay were conducted detect expression level messenger RNA tumor tissues cells. Transfection lncRNA OIP5‐AS1, or was performed investigate potential...
Fc fragment of IgG-binding protein (FCGBP) is differentially expressed in various tumors. However, the correlation between FCGBP and immune cell infiltration ovarian cancer remains unclear. expression was analyzed using The Cancer Genome Atlas (TCGA) pan-cancer data, profile Gene Expression Omnibus database. clinical prognostic value evaluated survival data from TCGA. Enrichment analysis performed R package clusterProfiler. Based on known scores for samples found TCGA, we association level...
Halocin C8 (HalC8) is an extremely stable and hydrophobic microhalocin with 76 amino acids, has a wide inhibitory spectrum against the haloarchaea. It derived from C-terminus of 283-amino-acid prepro-protein (ProC8), which was demonstrated by molecular cloning halC8 gene, verified N-terminal acid sequencing as well MALDI-TOF-MS analysis purified HalC8. The production this halocin controlled through both transcription regulation protein processing: transcripts HalC8 activity rapidly increased...
Oidium heveae HN1106, a powdery mildew (PM) that infects rubber trees, has been found to trigger disease resistance in Arabidopsis thaliana through ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1)-, PHYTOALEXIN DEFICIENT 4 (PAD4)- and salicylic acid (SA)-mediated signalling pathways. In this study, typical TOLL-INTERLEUKIN RECEPTOR, NUCLEOTIDE-BINDING, LEUCINE-RICH REPEAT (TIR-NB-LRR)-encoding gene, WHITE RUST RESISTANCE (WRR4B), was identified be required for the against O. Arabidopsis. The...
HomePlant DiseaseVol. 103, No. 7First Report of Leaf Blight on Stenotaphrum secundatum Caused by Nigrospora osmanthi in China PreviousNext DISEASE NOTESFirst ChinaS. S. Mei, Z. Y. Wang, J. Zhang, and W. RongS. MeiInstitute Tropical Agriculture Forestry, Hainan University, Haikou, Province, 570228, China, Wanghttp://orcid.org/0000-0002-6359-6978Institute Zhang†Corresponding authors: Zhang; E-mail Address: [email protected] Rong; protected]State Key Laboratory Plant Genomics, Institute...
Summary Oidium heveae , an obligate biotrophic pathogen of rubber trees ( Hevea brasiliensis ), causes significant yield losses worldwide. However, the molecular mechanisms underlying interplay between O. and remain largely unknown. In this study, we isolated strain, named HN1106, from cultivated H. in Hainan, China. We found that HN1106 triggers hypersensitive response a manner depends on effector‐triggered immunity proteins EDS1 (Enhanced Disease Susceptibility 1) PAD4 (Phytoalexin...
Halocin C8 (HalC8) is a stable microhalocin exhibiting strong antimicrobial activity against wide range of haloarchaea. HalI, 207-amino-acid peptide derived from the N terminus HalC8 preproprotein, immunity protein HalC8. In this study, molecular mechanism function HalI was investigated. Both pull-down and surface plasmon resonance assays revealed that directly interacted with HalC8, mixture purified readily formed heterocomplex, which verified by gel filtration. Interestingly, tended to...
Background. Epithelial ovarian cancer (EOC) has the lowest survival rate among female reproductive cancers present with symptoms of aggressive malignancies, poor prognosis, drug resistance and postoperative recurrence. The majority patients EOC are diagnosed at an advanced stage due to therapeutic challenges including lack early diagnosis effective targets for EOC. Methods. Pan-cancer analyses were performed explore features forkhead-box (FOX) A1 (FOXA1) using data from TCGA GTEx databases....
Objective To investigate the expression of annexin A6 (ANXA6) in cervical cancer cells and its effect mechanism on proliferation, invasion migration cells. Methods The mRNA protein levels ANXA6 normal cell line Ect1/E6E7 HeLa were determined by reverse transcription-polymerase chain reaction (RT-PCR) Western blot. divided into blank control group (no transfection), negative group(negative transfection) interference (siRNA-ANXA6 transfection). The proliferation was measured MTT assay....
Abstract Background: Epithelial ovarian cancer (EOC) has the lowest survival rate among female reproductive cancers present with symptoms of aggressive malignancies, poor prognosis, drug resistance and postoperative recurrence. The majority patients EOC are diagnosed at an advanced stage due to therapeutic challenges including lack early diagnosis effective targets for EOC. Methods: Pan-cancer analyses were performed explore features Forkhead box (FOX) A1 (FOXA1) using data from TCGA GTEx...
Vigna unguiculata belongs to the Legume family, and is an annual twining, herbaceous vine plant, which native Africa. V. most economically beneficial type of off-season vegetables in Hainan, China because its rich nutrients such as protein, minerals, dietary fiber, vitamins (Jayathilake et al. 2018). In April 2022, typical powdery mildew infection was observed on leaves Haikou, Hainan Province, (20°3'40.428"N, 110°19'45.217"E). More than 70% 13 plants displayed severe disease. The diseased...
HomePlant DiseaseVol. 104, No. 3First Report of Powdery Mildew (Pseudoidium pedaliacearum) on Stachytarpheta jamaicensis in China PreviousNext DISEASE NOTES OPENOpen Access licenseFirst ChinaHongying Ye, Bao Ying Lin, Wei Rong, and Shuangshuang MeiHongying YeHainan University, Haikou, Hainan Province, 570228, P.R. China, LinInstitute for Food Control, 570221, Ronghttp://orcid.org/0000-0002-7897-576XKey Laboratory Green Prevention Control Tropical Plant Diseases Pests, College Protection,...