- Particle physics theoretical and experimental studies
- Quantum Chromodynamics and Particle Interactions
- High-Energy Particle Collisions Research
- Cancer-related molecular mechanisms research
- Glioma Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- RNA modifications and cancer
- Perovskite Materials and Applications
- Neutrino Physics Research
- Plant Pathogenic Bacteria Studies
- Circular RNAs in diseases
- Brain Metastases and Treatment
- Gastrointestinal disorders and treatments
- Atomic and Subatomic Physics Research
- Plant-Microbe Interactions and Immunity
- MicroRNA in disease regulation
- Intraperitoneal and Appendiceal Malignancies
- Ferroptosis and cancer prognosis
- Endometrial and Cervical Cancer Treatments
- Plant Pathogens and Fungal Diseases
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Advanced NMR Techniques and Applications
- Epigenetics and DNA Methylation
- Wound Healing and Treatments
University of Science and Technology of China
2016-2025
China Mobile (China)
2025
Zhejiang Cancer Hospital
2015-2024
Shanghai Ninth People's Hospital
2016-2024
Shanghai Jiao Tong University
2016-2024
Chongqing Normal University
2024
Wenzhou Medical University
2024
Cancer Hospital of Chinese Academy of Medical Sciences
2020-2024
University of Chinese Academy of Sciences
2019-2024
Guangdong Medical College
2009-2024
Abstract Magnesium chelatase (MgCh) catalyzes the insertion of magnesium into protoporphyrin IX, a vital step in chlorophyll (Chl) biogenesis. The enzyme consists 3 subunits, MgCh I subunit (CHLI), D (CHLD), and H (CHLH). CHLI is an ATPase that mediates catalysis. Previous studies on have mainly focused model plant species, its functions other species not been well described, especially with regard to leaf coloration metabolism. In this study, we identified characterized mutant strawberry...
The sixth generation (6G) mobile communications have attracted substantial attention in the global research community of information and communication technologies (ICT). 6G systems are expected to support not only extended 5G usage scenarios, but also new such as integrated sensing (ISAC), artificial intelligence (AI) communication, ubiquitous connectivity. To realize this goal, channel characteristics must be comprehensively studied properly exploited, so promote design, standardization,...
Hybrid organic-inorganic lead halide perovskites are promising candidates for next-generation solar cells, light-emitting diodes, photodetectors, and lasers. The structural, dynamic, phase-transition properties play a key role in the performance of these materials. In this work, we use multitechnique experimental (thermal, X-ray diffraction, Raman scattering, dielectric, nonlinear optical) theoretical (machine-learning force field) approach to map phase diagrams obtain information on...
Long non-coding RNAs have recently become a key regulatory factor for cancers, whereas FER1L4, newly discovered long RNA, has been mostly studied in gastric carcinoma and colon cancer cases. The functions molecular mechanism of FER1L4 rarely reported glioma malignant phenotypes. In this study, it was found that the expression LncRNA is upregulated high-grade gliomas than low-grade cases high predicts poor prognosis gliomas. Meanwhile, vitro study suggests with SiRNA knockdown obviously...
Fertility sparing surgery has been extensively performed among patients with borderline ovarian tumors due to their age and favorable prognosis. Nevertheless, the prognosis obstetric outcomes in these remain uncertain. Thus, current study was carried out evaluate oncological safety fertility benefits of different subtypes various clinicopathological parameters. Young tumor an ≤40 years, who were admitted treated Zhejiang Cancer Hospital from January 1996 December 2016, enrolled this reviewed...
Glioblastoma is the most common and deadly primary brain tumor in adults. Low-dose,metronomic (LDM) temozolomide (TMZ) displays improved efficacy treatment of glioblastoma by targeting angiogenesis, but has a limited effect on recurrence. The antiangiogenesis drug ginsenoside Rg3 (RG3) main active ingredient ginseng, popular herbal medicine. Using an vitro rat model orthotopic glioma allograft, this study was to determine whether RG3 enhanced activity LDM TMZ glioblastoma. Our results showed...
Diffuse midline glioma with H3K27 M alteration is a primary malignant tumor located along the linear structure of brain, predominantly manifesting in children and adolescents. The mortality rate exceptionally high, mere 1 % 5-year survival for newly diagnosed patients. Beyond conventional surgery, radiotherapy, chemotherapy, novel approaches are imperative to enhance patient prognosis. This article comprehensively reviews current innovative treatment modalities provides updates on latest...
Heat transport in glasses across a wide range of temperature is vital for applications gate dielectrics and heat insulator. However, it remains poorly understood due to the challenges modeling vibrational anharmonicity below glass transition capturing configurational dynamics transition. Interestingly, recent calculations predicted that amorphous hafnia (a-HfO$_2$) exhibits an unusual drop thermal conductivity ($\kappa$) with temperature, contrasting typical rise or saturation observed upon...
Fc fragment of IgG-binding protein (FCGBP) is differentially expressed in various tumors. However, the correlation between FCGBP and immune cell infiltration ovarian cancer remains unclear. expression was analyzed using The Cancer Genome Atlas (TCGA) pan-cancer data, profile Gene Expression Omnibus database. clinical prognostic value evaluated survival data from TCGA. Enrichment analysis performed R package clusterProfiler. Based on known scores for samples found TCGA, we association level...
Background We aimed to examine the descriptive epidemiology and trends in burden of type 2 diabetes mellitus (T2DM). Methods Data were extracted from Global Burden Disease 2019 dataset. Estimated annual percentage changes (EAPCs) calculated assess incidence rate, mortality disability-adjusted life-years (DALYs) associated with T2DM. Measures stratified by sex, region, country, age social development index (SDI) value. Results The global age-standardized rate T2DM increased 1990 2019, an EAPC...
To assess the left ventricular (LV) longitudinal systolic and diastolic function in patients with dilated cardiomyopathy (DCM) by syngo Velocity Vector Imaging (VVI).Digital dynamic images of 30 DCM healthy subjects were collected; then velocity, strain, strain rate measured early late periods, time to peak recorded. The parameters two groups compared.All significantly lower than those normal group (P < 0.05-0.01), except that parameter was not different between > 0.05).VVI is a novel...
BACKGROUND:As a member of the CELF family, CELF1 (CUG-binding protein 1, CUGBP1) is involved in cardiac and embryonic development, skeletal muscle differentiation mammary epithelial cell proliferation.CELF1 also observed many kinds cancer may play great role tumorigenesis deterioration.However, expression mechanism its function human glioma remain unclear.METHODS: We examined 62 patients by immunohistochemistry Western blot.The association between clinicopathological characteristics was...
The main reason for the failure of malignant glioma treatment is local tumor recurrence.Tumor cells in hypoxic microenvironment activate HIF-1 α transcription, and thus promoting invasion metastasis one important reasons.In our previous study, we clearly established that borneol opens blood-brain barrier its related mechanism.However, effects itself on proliferation have not yet been elucidated.Therefore, this evaluated effect by constructing vivo SD rat brain model vitro human primary...