OBJECTIVE—Adiponectin and resistin, two recently discovered adipocyte-secreted hormones, may link obesity with insulin resistance and/or metabolic cardiovascular risk factors. We performed a cross-sectional study to investigate the association of adiponectin resistin inflammatory markers, hyperlipidemia, vascular reactivity an interventional whether atorvastatin mediates its beneficial effects by altering or levels. RESEARCH DESIGN AND METHODS—Associations among reactivity, were assessed...

OBJECTIVE—Endothelial dysfunction has been reported in type 2 diabetic patients and obese subjects with insulin resistance syndrome (IRS). This study evaluates the effects of weight reduction exercise on vascular reactivity macro- microcirculation IRS. RESEARCH DESIGN AND METHODS—We studied 24 (9 men 15 women, age 49.3 ± 1.9 years, BMI 36.7 0.94 kg/m2, mean SEM) IRS at baseline after 6 months exercise. Brachial artery flow-mediated dilation (FMD) response to sublingual glyceryltrinitrate...

Background: Particulate air pollution has been associated with several adverse cardiovascular health outcomes, and people diabetes may be especially vulnerable. One potential pathway is inflammation endothelial dysfunction—processes in which cell adhesion molecules inflammatory markers play important roles. Aim: To examine whether plasma levels of soluble intercellular molecule 1 (ICAM-1), vascular (VCAM-1) von Willebrand factor (vWF) were particle exposure 92 Boston area residents type 2...

We have investigated the effect of atorvastatin on endothelial function patients with diabetes and subjects at risk for type 2 in a 12-wk, prospective, randomized, placebo-controlled, double-blind clinical trial. The flow- mediated dilation (FMD; endothelium dependent) nitroglycerin-induced (endothelium independent) brachial artery vascular reactivity forearm skin were measured. FMD improved atorvastatin-treated, at-risk [median (25–75 percentile), 7.2% (2.9–9.6%) exit visit vs. 6.6%...

Background/Objectives: Both adiposity and Hashimoto’s thyroiditis (HT) are states of chronic inflammation. Adiposity may increase the risk thyroid nodules carcinoma. However, its role in patients with HT remains unclear. The connections among nodularity, adiposity, have not been explored. Aim: To investigate impact on nodularity HΤ to determine whether there any differences for cancer. Methods: This retrospective cohort study included 294 consecutive who were categorized according their body...

We examined the effects of high-dosage vitamin E treatment over a 12-month period on vascular reactivity micro- and macrocirculation left ventricular function in diabetic patients. Subjects (n = 89) were randomized to (1,800 IU daily) or placebo followed for 12 months. High-resolution ultrasound images used measure flow-mediated dilation (FMD; endothelium dependent) nitroglycerin-induced (NID; independent) brachial artery. Laser Doppler perfusion imaging was forearm skin. Left evaluated...

Background: The purpose of this study was to determine the prevalence thyroid carcinoma in patients who underwent ultrasound-guided fine needle aspiration biopsy (USgFNA) nodules island Cyprus. Ultrasound features as well presence autoimmune disease were evaluated risk factors for malignancy. Methods: 322 consecutively examined (272 females/50 males, age 13-81) USgFNA a referral endocrine clinic between July 2007 and 2009. ultrasonographic characteristics were: echogenicity, margin...

To determine the prevalence of lymph node (LN) metastasis and extrathyroidal extension (ETE) in patients with papillary thyroid microcarcinoma (PTMC) Cyprus to evaluate role preoperative ultrasound (U/S) examination.

ISEE-93 Introduction: Epidemiological studies suggest that people with diabetes are vulnerable to cardiovascular health effects associated exposure particle air pollution. Endothelial and vascular function is impaired in diabetics may be related increased risk. We examined whether endothelium-dependent independent reactivity were individuals without diabetes. Methods: Study subjects 270 participants clinical trials, before randomization therapy. Twenty-four hour average ambient levels of...

A widely discussed topic in the pathophysiology of thyroid nodules is role obesity that leads to increased systemic inflammatory markers. Leptin plays a vital forming and cancer through several mechanisms. Together with chronic inflammation, there an augmentation secretion tumor necrosis factor (TNF) cytokines interleukin 6 (IL-6), contributing development, progression metastasis. In addition, leptin exerts modulatory action growth, proliferation invasion carcinoma cell lines via activating...

Thyroid carcinoma patients, despite their generally excellent prognosis, have cervical nodal involvement at presentation in approximately 35% to 40% of cases. Furthermore, the vast majority 5% 20% recurrences are a locoregional nature. 1 Ultrasound (US) is commonly employed for both diagnosis and staging thyroid lymph nodes. The cytology suspicious nodes or nodules can then be verified by fine needle aspiration (FNA) cytology. US guidance FNA increases number representative samples as...

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

Adiposity may be associated with thyroid nodularity. However, its impact on the number of nodules and risk malignancy is unclear.

Subacute thyroiditis (SAT) is a thyroid inflammatory disease, whose pathogenesis still unclear. We report 52-year-old female with SAT after the third dose of COVID-19 mRNA vaccine BNT162b2 (Pfizer-BioNTech). This case was documented laboratory tests and ultrasound examination. She needed therapy during acute phase subsequently thyroxine supplementation.

Abstract Background Fine needle aspiration (FNA) cytology, the gold standard in assessing thyroid nodules, is limited by its inability to determine true risk of malignancy Thy 3 nodules. Most patients with Thy3 cytology undergo surgery establish a histologic diagnosis. The aims this study were evaluate prevalence examine ultrasound (US) characteristics that are associated high cancer and assess role real-time strain elastography. Methods Retrospective cohort 99 nodules who underwent...

Aim. Primary hyperparathyroidism (PHPT) often coexists with thyroid diseases. Current guidelines advise preoperative ultrasound (US) examination of the gland for nodular disease or concomitant malignancy but not evaluation autoimmune thyroiditis (AIT). The impact on clinical presentation and intraoperative course PHPT is clear. Material methods. We retrospectively assessed medical records 21 patients who underwent parathyroidectomy. Clinical, biochemical, ultrasonographic data were...

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)