A5076825992- Diabetes Management and Education
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Research
- Obesity and Health Practices
- Diabetes Treatment and Management
- Cardiovascular Health and Disease Prevention
- Adipokines, Inflammation, and Metabolic Diseases
- Diet and metabolism studies
- Chronic Disease Management Strategies
- Mobile Health and mHealth Applications
- Obesity, Physical Activity, Diet
- Diabetes and associated disorders
- Cardiovascular Health and Risk Factors
- Metabolism, Diabetes, and Cancer
- Racial and Ethnic Identity Research
- Adipose Tissue and Metabolism
- Peripheral Artery Disease Management
- Medication Adherence and Compliance
- Cultural Competency in Health Care
- Innovations in Medical Education
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cardiovascular Function and Risk Factors
- Global Public Health Policies and Epidemiology
- Genetic Associations and Epidemiology
- Pharmacology and Obesity Treatment
Harvard University
2014-2025
Brigham and Women's Hospital
2020-2024
Uppsala University
2024
University of Campania "Luigi Vanvitelli"
2024
University of Salerno
2024
ASL Roma
2024
Massachusetts General Hospital
2013-2023
Joslin Diabetes Center
2007-2017
Harvard University Press
2014
Environment and Health Group (United States)
2013
Abnormalities in vascular reactivity the micro- and macrocirculation are well established type 2 diabetes. However, little is known about changes those at risk for developing To address this situation, both was studied four age sex comparable groups: 30 healthy normoglycemic subjects with no history of diabetes a first-degree relative (controls), 39 one or parents (relatives), 32 impaired glucose tolerance (IGT), 42 patients without complications (diabetes). Laser Doppler perfusion imaging...
Microplastics and nanoplastics (MNPs) are emerging as a potential risk factor for cardiovascular disease in preclinical studies. Direct evidence that this extends to humans is lacking.
OBJECTIVE—Endothelial dysfunction has been reported in type 2 diabetic patients and obese subjects with insulin resistance syndrome (IRS). This study evaluates the effects of weight reduction exercise on vascular reactivity macro- microcirculation IRS. RESEARCH DESIGN AND METHODS—We studied 24 (9 men 15 women, age 49.3 ± 1.9 years, BMI 36.7 0.94 kg/m2, mean SEM) IRS at baseline after 6 months exercise. Brachial artery flow-mediated dilation (FMD) response to sublingual glyceryltrinitrate...
OBJECTIVE—We measured plasma markers of endothelial dysfunction, vascular inflammation, and pro-coagulation in obese Hispanic/Latino children adolescents with normal glucose tolerance determined their relationship to body composition indexes lipid metabolism. RESEARCH DESIGN AND METHODS—A total 38 lean or Hispanic (10–18 years age) were selected. The overweight group (n = 21) had a BMI >85th percentile for age sex, the 17) between 25th 50th percentiles. Studies included an oral test,...
The effect of metformin (1000 mg twice a day) on markers endothelial activation, inflammation, and coagulation was investigated in subjects with impaired glucose tolerance (IGT) 16-wk, randomized, placebo-controlled, double-blind study. Soluble intercellular adhesion molecule, soluble vascular cell C-reactive protein, TNFα, von Willebrand factor, tissue plasminogen activator were measured at baseline the end trial. Subjects IGT (n = 55, 14 males 41 females), aged 48.4 ± 9.6 yr body mass...
OBJECTIVE: Using von Willebrand Factor (vWF) as a marker of endothelial function, previous studies have shown that the development microalbuminuria is associated with onset dysfunction in individuals type 2 diabetes. We tested hypothesis already evident normoalbuminuric RESEARCH DESIGN AND METHODS: used laser Doppler imaging scanning to measure vasodilation forearm skin response iontophoresis 1% acetylcholine (endothelium-dependent) and sodium nitroprusside (endothelium-independent)....
In the U.S., poverty has been linked to both obesity and disease burden. Latinos in U.S. are disproportionately affected by poverty, over past 10 years, percentage of overweight Latino youth approximately doubled. Buying low-cost food that is calorie-dense filling obesity. Low-income individuals tend favor energy-dense foods because their low cost, economic decisions made during purchasing have physiologic repercussions. Diets based on be high processed staples, such as refined grains, added...
Abstract Intimate partner violence (IPV) increases the risk of homelessness and housing instability, particularly among Latine immigrant survivors in USA. Latina women face disproportionate impacts IPV heightened risks for yet remain underrepresented literature, where methodologies regularly fail to center their voices lived experiences. This study addresses this gap by utilizing Participatory Action Research (PAR) investigate experiences ( N = 14) through in‐depth interviews conducted...
We examined the effects of high-dosage vitamin E treatment over a 12-month period on vascular reactivity micro- and macrocirculation left ventricular function in diabetic patients. Subjects (n = 89) were randomized to (1,800 IU daily) or placebo followed for 12 months. High-resolution ultrasound images used measure flow-mediated dilation (FMD; endothelium dependent) nitroglycerin-induced (NID; independent) brachial artery. Laser Doppler perfusion imaging was forearm skin. Left evaluated...
In this secondary analysis, we examined whether older adults with diabetes (aged 60-75 years) could benefit from self-management interventions compared younger adults. Seventy-one community-dwelling and 151 were randomized to attend a structured behavioral group, an attention control or one-to-one education.We measured A1C, self-care (3-day pedometer readings, blood glucose checks, frequency of self-care), psychosocial factors (quality life, distress, frustration self-care, depression,...
Background Structural equation modeling (SEM) can help understanding complex functional relationships among obesity, non-alcoholic fatty liver disease (NAFLD), family history of targeted metabolomics and pro-inflammatory markers. We tested two hypotheses: 1) If obesity precedes an excess free acids that increase oxidative stress mitochondrial dysfunction, there would be serum acylcarnitines, amino cytokines in obese subjects. Acylcarnitines related to will induce insulin resistance. 2) a...
Differences in the prevalence of four diabetes subgroups have been reported Mexico compared to other populations, but factors that may contribute these differences are poorly understood. Here, we estimate and evaluate their correlates with indicators social disadvantage using data from national representative surveys.