A5004046846- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Inflammasome and immune disorders
- Liver Disease Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Diet and metabolism studies
- Biochemical Analysis and Sensing Techniques
- Metabolomics and Mass Spectrometry Studies
- Diet, Metabolism, and Disease
- Olfactory and Sensory Function Studies
- Dysphagia Assessment and Management
- Cardiovascular Health and Disease Prevention
- Gut microbiota and health
- Systemic Lupus Erythematosus Research
- Birth, Development, and Health
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- Intensive Care Unit Cognitive Disorders
- Probiotics and Fermented Foods
- Vagus Nerve Stimulation Research
- Gastroesophageal reflux and treatments
- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
Hospital General de México
2017-2025
GTx (United States)
2017
Sucralose consumption alters microbiome and carbohydrate metabolism in mouse models. However, there are no conclusive studies humans. Our goals were to examine the effect of sucralose on intestinal abundance bacterial species belonging Actinobacteria, Bacteroidetes, Firmicutes explore potential associations between profiles glucose insulin blood levels healthy young adults. In this open-label clinical trial, volunteers randomly drank water, as a control (n = 20), or 48 mg every day for ten...
Objectives When dealing with children and adolescents living obesity, it is vital to be aware that exercise provides benefits in the prevention control of non-communicable diseases general well-being. The growing prevalence childhood obesity makes necessary develop strategies aimed at controlling barriers limit performance exercise, which why we designed a plan prescription through videos could accessible, free, for home, as complement multidisciplinary intervention program lifestyle change....
Background Structural equation modeling (SEM) can help understanding complex functional relationships among obesity, non-alcoholic fatty liver disease (NAFLD), family history of targeted metabolomics and pro-inflammatory markers. We tested two hypotheses: 1) If obesity precedes an excess free acids that increase oxidative stress mitochondrial dysfunction, there would be serum acylcarnitines, amino cytokines in obese subjects. Acylcarnitines related to will induce insulin resistance. 2) a...
Abstract Background Non-nutritive sweeteners (NNS) are widely consumed by humans due to their apparent innocuity, especially sucralose. However, several studies link sucralose consumption weight gain and metabolic derangements, although data still contradictory. Objective To determine the effect of acute chronic on insulin glucose profiles in young healthy adults. Material methods This was a randomized, parallel, double-blind, placebo-controlled trial conducted adults from 18 35 years old,...
Background and Objectives: Metabolic-dysfunction-associated steatotic liver disease or MASLD is the main cause of chronic diseases in children, it estimated to affect 35% children living with obesity. This study aimed identify metabolic phenotypes associated two advanced stages (hepatic steatosis hepatic plus fibrosis) Mexican Materials Methods: a cross-sectional analysis derived from randomized clinical trial conducted adolescents obesity aged 8 16 years. Anthropometric biochemical data...
By end December of 2021, COVID-19 has infected around 276 million individuals and caused over 5 deaths worldwide. Infection results in dysregulated systemic inflammation, multi-organ dysfunction, critical illness. Cells the central nervous system are also affected, triggering an uncontrolled neuroinflammatory response. Low doses glucocorticoids, administered orally or intravenously, reduce mortality among moderate severe patients. However, low by these routes do not reach therapeutic levels...
<ns3:p>Background Coronavirus disease 2019 (COVID-19) has created the need to evaluate drugs such as favipiravir (FPV), an antiviral inhibitor of RNA-dependent RNA-polymerase (RdRp), and Maraviroc (MVC), antiretroviral that antagonizes chemokine receptor CCR5, which could affect modulation inflammation viral replication in treatment COVID-19. We sought effect MVC and/or FPV plus systemic steroid (SS) <ns3:italic>vs.</ns3:italic> SS alone on load progression critical disease. Methods Sixteen...
Objective The aim of this study was to estimate the heritability (h2) and genetic correlation (ρG) between GERD symptoms severity, metabolic syndrome components, inflammation markers in Mexican families. Methods Cross-sectional which included 32 extended families resident Mexico City. severity assessed by ReQuest Practice questionnaire. Heritability were determined using Sequential Oligogenic Linkage Analysis Routines software. Results 585 subjects included, mean age 42 (±16.7) years, 57%...
To evaluate the utility of predicting nonalcoholic fatty liver disease (NAFLD) and obesity by retinal vascular changes (RVC) found in fundoscopy to determine whether this is related a low-grade inflammatory process.We carried out cross-sectional analysis that included 152 (ages 18-45 years) patients divided into four groups: NAFLD BMI less than 25, absence more 30, 30. Retinal fundoscopy, hepatic ultrasound, metabolic profile, cytokine measurement were performed. We calculated odds ratio...
<ns3:p>Background Coronavirus disease 2019 (COVID-19) has created the need to evaluate drugs such as favipiravir (FPV), an antiviral inhibitor of RNA-dependent RNA-polymerase (RdRp), and Maraviroc (MVC), antiretroviral that antagonizes chemokine receptor CCR5, which could affect modulation inflammation viral replication in treatment COVID-19. We sought effect MVC and/or FPV plus systemic steroid (SS) <ns3:italic>vs.</ns3:italic> SS alone on load progression critical disease. Methods Sixteen...
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Abstract COVID-19 has produced more than 176 million infected individuals and almost 3.2 deaths worldwide. The infection results in a dysregulated systemic inflammation, multi-organ dysfunction, critical illness. Cells of the central nervous system (CNS) are also affected triggering neuroinflammatory response.Low doses glucocorticoids (GCs) orally or intravenously administered been proved to reduce mortality moderate severe patients. However, low by those routes do not reach therapeutic...
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Abstract Background : Multiple studies have now established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce...