A5007873477- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Inflammasome and immune disorders
- Reproductive tract infections research
- Parasitic Infections and Diagnostics
- SARS-CoV-2 and COVID-19 Research
- RNA and protein synthesis mechanisms
- Molecular Biology Techniques and Applications
- Biosensors and Analytical Detection
- Protein Structure and Dynamics
- Research on Leishmaniasis Studies
- Polyamine Metabolism and Applications
- SARS-CoV-2 detection and testing
- Ruminant Nutrition and Digestive Physiology
- Amoebic Infections and Treatments
- Enzyme Structure and Function
- Sepsis Diagnosis and Treatment
- RNA modifications and cancer
- RNA Research and Splicing
- Climate change and permafrost
Hospital General de México
2020-2024
Universidad Autónoma de la Ciudad de México
2015-2023
<ns3:p>Background Coronavirus disease 2019 (COVID-19) has created the need to evaluate drugs such as favipiravir (FPV), an antiviral inhibitor of RNA-dependent RNA-polymerase (RdRp), and Maraviroc (MVC), antiretroviral that antagonizes chemokine receptor CCR5, which could affect modulation inflammation viral replication in treatment COVID-19. We sought effect MVC and/or FPV plus systemic steroid (SS) <ns3:italic>vs.</ns3:italic> SS alone on load progression critical disease. Methods Sixteen...
Introduction: The enzyme lactate dehydrogenase (LDH) is a good marker of general hyperinflammation correlated with mortality for COVID-19, and therefore used in prognosis tools. In current COVID-19 clinical randomized trial (CRT), the blood level LDH was selected as an inclusion criterion. However, decreased during pandemic; hence, impact this decrease on prognostic value evaluated. Methods: Data levels 843 patients were obtained analyzed. Relative risk, standard error receiver operating...
To understand whether protein Tv-PSP1 from Trichomonas vaginalis recognizes mRNA parasite stem-loop structures, we conducted REMSA and intrinsic fluorescence assays. We found the recombinant structure, determined with X-ray crystallography, showed unusual thermal stability of quaternary associated a disulfide bridge CYS76-CYS104. gain deeper insight into interaction stem-loops (mRNAsl) its relationship stability, also used an integrated computational protocol that combined molecular dynamics...
<ns3:p>Background Coronavirus disease 2019 (COVID-19) has created the need to evaluate drugs such as favipiravir (FPV), an antiviral inhibitor of RNA-dependent RNA-polymerase (RdRp), and Maraviroc (MVC), antiretroviral that antagonizes chemokine receptor CCR5, which could affect modulation inflammation viral replication in treatment COVID-19. We sought effect MVC and/or FPV plus systemic steroid (SS) <ns3:italic>vs.</ns3:italic> SS alone on load progression critical disease. Methods Sixteen...
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Abstract Background : Multiple studies have now established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce...