A5089320629- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Inflammasome and immune disorders
- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Diabetes and associated disorders
- Immune Cell Function and Interaction
- SARS-CoV-2 and COVID-19 Research
- Liver Disease and Transplantation
- Wound Healing and Treatments
- Pressure Ulcer Prevention and Management
- Electrical and Bioimpedance Tomography
- Infrared Thermography in Medicine
- Laser-induced spectroscopy and plasma
- Hepatitis C virus research
- T-cell and B-cell Immunology
- Urologic and reproductive health conditions
- Pancreatitis Pathology and Treatment
- Sepsis Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- IL-33, ST2, and ILC Pathways
- Animal Diversity and Health Studies
- Hops Chemistry and Applications
- Alcohol Consumption and Health Effects
Hospital General de México
2017-2024
Universidad Nacional Autónoma de México
2017-2020
Universidad Panamericana
2018
Abstract Background Wound healing monitoring and timely decision‐making are critical for wound classification. Tryptophan (Tr) intrinsic fluorescence, detected at 295/340 nm, provides a noninvasive approach assessment. Our previous work demonstrated that this autofluorescence is associated with keratinocytes in highly proliferative state vitro. Objective We investigated the correlation between Tr fluorescence key parameters, including re‐epithelialization, fibrosis, neovascularization, acute...
Hepatic cirrhosis is a major cause of morbidity and mortality worldwide due to hepatitis C, alcoholism fatty liver disease associated with obesity. Assessment hepatic fibrosis relies in qualitative histological evaluation biopsy samples. This method time-consuming depends on the histopathologists' interpretation. In last decades, non-invasive techniques were developed detect monitor fibrosis. Laser-induced breakdown spectroscopy (LIBS) good candidate for real-time, independent fast technique...
<ns3:p>Background Coronavirus disease 2019 (COVID-19) has created the need to evaluate drugs such as favipiravir (FPV), an antiviral inhibitor of RNA-dependent RNA-polymerase (RdRp), and Maraviroc (MVC), antiretroviral that antagonizes chemokine receptor CCR5, which could affect modulation inflammation viral replication in treatment COVID-19. We sought effect MVC and/or FPV plus systemic steroid (SS) <ns3:italic>vs.</ns3:italic> SS alone on load progression critical disease. Methods Sixteen...
Introduction: The enzyme lactate dehydrogenase (LDH) is a good marker of general hyperinflammation correlated with mortality for COVID-19, and therefore used in prognosis tools. In current COVID-19 clinical randomized trial (CRT), the blood level LDH was selected as an inclusion criterion. However, decreased during pandemic; hence, impact this decrease on prognostic value evaluated. Methods: Data levels 843 patients were obtained analyzed. Relative risk, standard error receiver operating...
High alcohol intake on weekends (binge drinking) is more frequent in young adults, who could undergo early liver damage. Alcohol-induced damage characterized by polymorphonuclear cell (PMN) infiltration, which can be represented the peripheral blood altered trafficking and activation profiles.To evaluate PMN immunophenotypic profiles people with a binge drinking pattern.People (n = 18, 8 females) or at low risk 16, 13 based their AUDIT HEPCA scores were studied. Hematic biometry enzyme tests...
<ns3:p>Background Coronavirus disease 2019 (COVID-19) has created the need to evaluate drugs such as favipiravir (FPV), an antiviral inhibitor of RNA-dependent RNA-polymerase (RdRp), and Maraviroc (MVC), antiretroviral that antagonizes chemokine receptor CCR5, which could affect modulation inflammation viral replication in treatment COVID-19. We sought effect MVC and/or FPV plus systemic steroid (SS) <ns3:italic>vs.</ns3:italic> SS alone on load progression critical disease. Methods Sixteen...
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Non-subjective, minimally-invasive, and quantifying techniques may support development evaluation of a fibrosis regression treatment. The build-up extracellular matrix in liver result on changes the endogenous fluorescence tissue. In this work, we evaluate excitation/emission UV range for several bulk samples murine hepatic tissue preserved different media. Chemical tissue, caused by formaldehyde preservation, alter spectra. To avoid these drawbacks, phosphate-buffered saline (PBS) or...
Background: Natural killer cells (NKC) are a major component of the innate immune response to HCV, mediating their effects through TRAIL and IFN-γ. However, function is diminished in chronic HCV patients (HCVp). Prolactin an immunomodulatory hormone capable activating NKC. Objective: The study aims explore if hyperprolactinemia can activate NKC HCVp. Methods: We treated twelve HCVp (confidence level =95%, power =80%) for 15 days with Levosulpiride plus Cimetidine induce mild...
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Background: Animal models for hepatic fibrosis are currently used clinical studies, and research works aimed to the progression regression of disease.In these, is evaluated using histopathological assessment with high variability inter-and intra-observers.Digital morphometry in space color LAB could reduce this variability; however, its correlation degree unknown.Objective: The objective study was analyze between digital images biopsies a murine model.Materials methods: We performed...
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Antecedentes: La prostatectomía radical asistida por robot se ha posicionado como el abordaje de elección en tratamiento del cáncer próstata.Objetivo: Comparar los resultados la utilizando Retzius-Sparing (RS) contra Frankfurt modificado (FM).Método: Se describen desenlaces perioperatorios
Abstract Multiple studies have established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce migration...
Abstract Background : Multiple studies have now established that hyperinflammatory response induced by SARS CoV-2 is a main cause of complications and death in infected subjects. Such dysfunctional immune has been described as dysregulated exacerbated production cytokines chemokines attracts activates inflammatory cells, which start sustain pulmonary systemic damage, thus causing lead to multi organ failure death. Therefore, we suggest blocking key inflammation receptors could help reduce...