A5014363376- Pharmaceutical Practices and Patient Outcomes
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Renal Transplantation Outcomes and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Patient Safety and Medication Errors
- Cardiac Arrest and Resuscitation
- Health Systems, Economic Evaluations, Quality of Life
- Medication Adherence and Compliance
- Nutrition and Health in Aging
- Renal Diseases and Glomerulopathies
- Cardiovascular and exercise physiology
- Mechanical Circulatory Support Devices
- Pharmacy and Medical Practices
- Cardiac, Anesthesia and Surgical Outcomes
- Parvovirus B19 Infection Studies
- Pregnancy and Medication Impact
- Chemotherapy-induced cardiotoxicity and mitigation
- Blood Pressure and Hypertension Studies
- Frailty in Older Adults
- Acute Myocardial Infarction Research
- Geriatric Care and Nursing Homes
- Pain Management and Treatment
- Patient-Provider Communication in Healthcare
University of Wisconsin Health
2016-2022
Highland Community College - Illinois
2017-2022
University of Wisconsin–Madison
2014-2016
UW Health University Hospital
2010-2014
UConn Health
2002-2011
University of Connecticut
1986-2010
Case Western Reserve University
2008-2010
KU Leuven
1996
Brigham and Women's Hospital
1994
University of Hartford
1986
Original Article from The New England Journal of Medicine — Effect Short-Term Infusion Sodium Nitroprusside on Mortality Rate in Acute Myocardial Infarction Complicated by Left Ventricular Failure Results a Veterans Administration Cooperative Study
Heart failure (HF) may contribute to the development of functional decline and frailty in older adults. Sixty HF patients with an ejection fraction ≤40% evaluated 2004 2005 were reevaluated 2008. Six‐minute walk distance (6MW), score, biomarkers (25‐hydroxyvitamin D, C‐reactive protein, interleukin‐6 [IL‐6]) measured. Participants categorized at baseline follow‐up into 3 groups: nonfrail/normal endurance (NF/NE), nonfrail/low (NF/LE) frail/low (F/LE). Survival time was assessed according...
Recent evidence suggests that de novo donor-specific antibodies (dnDSA) are associated with antibody-mediated rejection (ABMR) and graft failure after kidney transplantation. The effects of induction immunosuppression on dnDSA unknown.The study population comprised 114 consecutive moderately sensitized (positive DSA negative flow crossmatch) recipients who received deceased donor renal transplants between December 2009 November 2011. Patients were divided into two groups based...
The Survival and Ventricular Enlargement (SAVE) Study demonstrated that long-term administration of the angiotensin-converting enzyme inhibitor captopril to recent survivors myocardial infarction with left ventricular dysfunction resulted in a reduction cardiovascular mortality morbidity. Analysis multiple subgroups baseline demongraphics (older age) clinical characteristics (such as prior MI, history diabetes or hypertension), have previously been associated higher risk events, were greater...
Patients with heart failure (HF) are at increased risk for frailty, and identification is challenging. The authors assessed the distance on 6‐minute walk test (6MWT) as a measure of frailty in 60 older HF patients (ejection fraction ≤40%) compared phenotype (FP). Scores were dichotomized to frail (F) or nonfrail (NF), results 6MWT low endurance (LE) normal (NE). FP moderate agreement (κ=0.57, confidence interval [CI], 0.36–0.79; age‐adjusted κ=0.54, 95% CI, 0.33–0.76);25% participants...
Background Goal tacrolimus concentrations for the prevention of rejection in sensitized renal transplant recipients are not well established. Methods We evaluated association between discharge trough concentration and incidence biopsy-proven acute (BPAR) 216 moderately (negative flow crossmatch positive donor-specific antibodies) treated with tacrolimus. Results At transplant, mean±standard deviation (SD) peak panel-reactive antibody was 60±33 median level a mean fluorescence intensity 710...
The high-value pharmacy enterprise (HVPE) framework and constituent best practice consensus statements are presented, the methods used to develop framework's 8 domains described. A panel of leaders an evidence- expert opinion-based approach define core aspirational elements that should be established within contemporary health-system enterprises by calendar year 2025. Eight HVPE were identified: Patient Care Services; Business Ambulatory Specialty Pharmacy Inpatient Operations; Safety...
To compare the efficacy of a single dose basiliximab with two doses in preventing acute rejection selected low-risk renal transplant recipients.This observational study 760 kidney recipients considered to be at low immunologic risk (peak panel reactive antibody less than 10%) compared patient and graft outcomes following single-dose versus two-dose regimen basiliximab.No differences were found survival (92% vs 92%, p=0.6), (86% 83%, p=0.2), (cellular [4% 7%, p=0.2], antibody-mediated [19%...
Results of a pilot project to improve the safety and efficiency discharge process by adding daily pharmacist review preparation medication orders an existing reconciliation workflow are reported.Due patient capacity issues, pharmacy department large tertiary medical center implemented changes workflow. A steering committee was established, with subgroups responsible for development, electronic record enhancement, data collection designated. Patients admitted 5 hospitalist services, 1...
Abstract Purpose Improve patient access to clinical pharmacy services and decrease pharmacist technical task workload in primary care (PC) clinics. Summary Due concerns with the amount of tasks performed by University Wisconsin Health PC pharmacists negatively impacting their capacity for patients perform tasks, department piloted a new technician role that involved completion previously pharmacists. daily activities were identified through shadowing quantified 4-week period work sampling. A...
Purpose: To evaluate whether active learning-based training in teach-back and plain language (TBPL) techniques can lead to observable changes patient-centered practices pharmacist-patient counseling.
 Methods: All pharmacists direct patient care roles, inpatient outpatient, were required complete a didactic module workshop / webinar or small group training. The modalities incorporated elements of adult education theory. Following completion, surveyed assess their ability, confidence...
Background: While hospital beds continue to decline as patients previously treated inpatients are stabilized in ambulatory settings, the number of critical care available United States continues rise. Growth pharmacy student graduation, postgraduate year 2 (PGY2 CC) residency programs, and positions has also increased. There is a perception that trained pharmacist market saturated, yet this not been evaluated since rise graduates programs. Purpose: To describe current program directors (CC...
Steps taken by a large health system to require certification for all pharmacists in direct patient care roles are detailed.Major supply chain changes and rising payer expectations reshaping pharmacy practice, resulting expanded responsibilities heightened need specialized practice areas. In response, the leadership team at UW Health, integrated of University Wisconsin-Madison, used an iterative process "rolling" FAQ format develop implement requirement. Key decisions during included accept...
Journal Article Interprofessional development and implementation of a pharmacist professional advancement recognition program Get access David Hager, Pharm.D., BCPS, BCPS UW Health–University Hospital, Madison, WI Address correspondence to Dr. Hager (dhager@uwhealth.org). Search for other works by this author on: Oxford Academic Google Scholar Eric Chmielewski, Chmielewski Pharm.D. student Andrea L. Porter, Pharm.D, Pharm.D University Wisconsin–Madison School Pharmacy, Sarah Brzozowski,...
The Pharmacy Quality Alliance's definition of proportion days covered (PDC) and medication possession ratio (MPR) have not been examined as potential quality measures in the kidney transplant recipient population.To (a) describe frequency distribution MPR PDC using mycophenolic acid products a real-world population (b) evaluate associations between with late (> 90 after transplantation) biopsy-proven acute rejection (BPAR).This was retrospective cohort study combining data from Wisconsin...