Jian‐Jhong Wang

ORCID: 0000-0002-5530-0719
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About
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Research Areas
  • Acute Kidney Injury Research
  • Cardiac Arrest and Resuscitation
  • Chronic Kidney Disease and Diabetes
  • Hemodynamic Monitoring and Therapy
  • Cardiac, Anesthesia and Surgical Outcomes
  • Hormonal Regulation and Hypertension
  • Sepsis Diagnosis and Treatment
  • Adrenal and Paraganglionic Tumors
  • Dialysis and Renal Disease Management
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • Electrolyte and hormonal disorders
  • Renal and Vascular Pathologies
  • Diabetes Treatment and Management
  • Respiratory Support and Mechanisms
  • Cardiac Arrhythmias and Treatments
  • Lipoproteins and Cardiovascular Health
  • Immune Response and Inflammation
  • Nosocomial Infections in ICU
  • Atrial Fibrillation Management and Outcomes
  • Peptidase Inhibition and Analysis
  • Cardiac electrophysiology and arrhythmias
  • Health Systems, Economic Evaluations, Quality of Life
  • Adrenal Hormones and Disorders
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Retinal Diseases and Treatments

Chi Mei Medical Center
2015-2019

National Health Research Institutes
2018

National Taiwan University Hospital
2015

National Taiwan University
2015

Constitutive activation of the Wnt pathway/β-catenin signaling may be important in aldosterone-producing adenoma (APA). However, significant gaps remain our understanding prevalence and clinical outcomes after adrenalectomy APA patients harboring CTNNB1 mutations. The molecular expression CYP11B2 gonadal receptors adenomas were also explored. Adenomas from 219 (95 men; 44.2%; aged 50.5 ± 11.9 years) showed a high rate somatic mutations (n = 128, 58.4%). majority them harbored KCNJ5 116,...

10.1038/srep39121 article EN cc-by Scientific Reports 2017-01-19

Acute kidney injury (AKI) after cardiovascular surgery is a serious complication. Little known about the ability of novel biomarkers in combination with clinical risk scores for prediction advanced AKI. In this prospectively conducted multicenter study, urine samples were collected from 149 adults at 0, 3, 6, 12 and 24 h surgery. We measured urinary hemojuvelin (uHJV), molecule-1 (uKIM-1), neutrophil gelatinase-associated lipocalin (uNGAL), α-glutathione S-transferase (uα-GST) π-glutathione...

10.1186/s13054-018-2035-8 article EN cc-by Critical Care 2018-04-26

The aim of this retrospective, nationwide, matched cohort study was to investigate the association serous retinal detachment with having end-stage renal disease (ESRD) while on dialysis. included 94,024 patients ESRD dialysis registered between January 2000 December 2009 in Taiwan National Health Insurance Research Database. An age- and sex-matched control group comprised selected from Longitudinal Database 2000. Information for each patient collected index date until 2011. Twenty-seven 11...

10.1371/journal.pone.0180133 article EN cc-by PLoS ONE 2017-06-28

Acute kidney injury (AKI) carries an increasing incidence rate worldwide and increases the risk of developing end-stage renal disease (ESRD) as well medical expenses during post-AKI course. The Taiwan Consortium for Kidney Injury Renal Diseases (CAKs) has thus launched a nationwide epidemiology prognosis dialysis-requiring acute (NEP-AKI-D) study, which prospectively enrols critically ill patients with AKI. Through thoroughly evaluating prognostic factors AKI, we hope to lower AKI ESRD from...

10.1111/nep.12670 article EN Nephrology 2015-11-17

Although statin treatment is recommended for patients with chronic kidney disease (CKD) stages I⁻IV, its potential benefits have not been reported in advanced CKD patients. Non-diabetic (pre-dialysis patients, estimated glomerular filtration rate <15 mL/min/1.73 m²) were enrolled from a National Health Insurance Research Database population of 23 million. Statin users and non-users matched using propensity scoring analyzed Cox proportional hazards models, taking mortality as competing risk...

10.3390/jcm7090285 article EN Journal of Clinical Medicine 2018-09-17

Postoperative acute kidney injury (AKI) is common following cardiac surgery (CS). Body weight (BW) may be an amenable variable by representing the summation of nutritional and fluid status. However, predictive role perioperative BW changes in CS patients with severe postoperative AKI never explored. This study aimed to evaluate this association.This was conducted using a prospectively collected multicenter cohort, NSARF (National Taiwan University Hospital Study Group on Acute Renal Failure)...

10.1371/journal.pone.0187280 article EN cc-by PLoS ONE 2017-11-17

The influence of acute kidney injury (AKI) on subsequent incident atrial fibrillation (AF) has not yet been fully addressed. This retrospective nationwide cohort study was conducted using Taiwan’s National Health Insurance Research Database from 1 January 2000 to 31 December 2010. A total 41,463 patients without a previous AF, mitral valve disease, and hyperthyroidism who developed de novo dialysis-requiring AKI (AKI-D) during their index hospitalization were enrolled. After propensity score...

10.3390/jcm7090248 article EN Journal of Clinical Medicine 2018-08-29

Objectives To examine whether urinary excretion of cysteine-rich protein 61 (Cyr61), an acknowledged proinflammatory factor in kidney pathologies, increases chronic disease (CKD) and is associated with subsequent rapid function decline. Design An observational cohort study. Setting In the nephrology outpatient clinics a tertiary hospital Taiwan. Participants We enrolled 138 adult CKD outpatients (n=12, 32, 18, 29 stages 1, 2, 3a, 3b, 4 5 CKD, respectively) between February October 2014...

10.1136/bmjopen-2021-051165 article EN cc-by-nc BMJ Open 2021-10-01

The purpose of pulse analysis system is to provide a platform for researchers analyze, share, and store patients' data. Researchers can use the extract features through Fast Fourier Transform (FFT), harmonics, Ensemble Empirical Mode Decomposition (EEMD), then take advantage former result gather statistics classify patients two-sample t-test or paired-sample t-test. A group working in National Taiwan University Hospital (NTUH) have done an experiment examine whether find out acute kidney...

10.1109/imws-bio.2015.7303795 article EN 2015-09-01

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

10.1530/endoabs.35.oc2.5 article EN Endocrine Abstracts 2014-04-17
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