- SARS-CoV-2 and COVID-19 Research
- Bacteriophages and microbial interactions
- Protein purification and stability
- Cell Image Analysis Techniques
- SARS-CoV-2 detection and testing
- Gut microbiota and health
- vaccines and immunoinformatics approaches
- Bacillus and Francisella bacterial research
Russian Academy of Sciences
2022
Centre for Research and Development
2022
Institute of Bioorganic Chemistry
2018
Microbiome spectra serve as critical clues to elucidate the evolutionary biology pathways, potential pathologies, and even behavioral patterns of host organisms. Furthermore, exotic sources microbiota represent an unexplored niche discover microbial secondary metabolites. However, establishing bacterial functionality is complicated by intricate web interactions inside microbiome. Here we apply ultrahigh-throughput (uHT) microfluidic droplet platform for activity profiling entire oral...
Various types of COVID-19 vaccines, including adenovirus, mRNA, and inactivated ones, have been developed approved for clinical use worldwide. Inactivated vaccines are produced using a proven technology that is widely used the production prevention control infectious diseases, influenza poliomyelitis. The development whole-virion commonly includes several stages: cellular viral biomass in cell culture; inactivation virus; filtration ultrafiltration; chromatographic purification antigen;...
BACKGROUND: SARS-CoV-2 vaccine immunogenicity is evaluated in neutralization test with live virus. It performed a biosafety level 3 zone because requires virus stage. Therefore, control laboratories should be certified for this class of work. The development technology based on enzyme-linked immunosorbent assay as an analogue the reaction makes it possible to create immunobiological product shorter time and conditions without special requirements laboratories. AIM: Development assessing by...