A5079134443- Natural Compound Pharmacology Studies
- Anaerobic Digestion and Biogas Production
- Liver Diseases and Immunity
- Membrane Separation Technologies
- Systemic Lupus Erythematosus Research
- Microbial Metabolic Engineering and Bioproduction
- Liver Disease Diagnosis and Treatment
- Phytochemistry and Biological Activities
- Allelopathy and phytotoxic interactions
- Wastewater Treatment and Nitrogen Removal
- Microscopic Colitis
- Microbial Fuel Cells and Bioremediation
- Microbial bioremediation and biosurfactants
- Environmental Chemistry and Analysis
- Water-Energy-Food Nexus Studies
- Drug Transport and Resistance Mechanisms
- Gout, Hyperuricemia, Uric Acid
- ATP Synthase and ATPases Research
- Infant Nutrition and Health
- Inflammatory Bowel Disease
- T-cell and Retrovirus Studies
- Essential Oils and Antimicrobial Activity
- Hops Chemistry and Applications
- Biofuel production and bioconversion
- Breastfeeding Practices and Influences
Universidade do Estado da Bahia
2022
University of Minho
2003-2020
Universidade de São Paulo
2017-2020
Universidade Brasil
2020
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2018
Wageningen University & Research
2015
Lipids can be anaerobically digested to methane, but methanogens are often considered highly sensitive the long-chain fatty acids (LCFA) deriving from lipids hydrolysis. In this study, effect of unsaturated (oleate [C18:1]) and saturated (stearate [C18:0] palmitate [C16:0]) LCFA toward methanogenic archaea was studied in batch enrichments pure cultures. Overall, oleate had a more stringent on than LCFA, degree tolerance different among distinct species methanogens. Methanobacterium...
Fat, oils, and grease present in complex wastewater can be readily converted to methane, but the energy potential of these compounds is not always recyclable, due incomplete degradation long chain fatty acids (LCFA) released during lipids hydrolysis. Oleate (C18:1) generally dominant LCFA lipid-containing wastewater, its conversion anaerobic bioreactors results palmitate (C16:0) accumulation. The reason why oleate continuously without further via β-oxidation still unknown. In this work,...
Degradation of long-chain fatty acids (LCFAs) in methanogenic environments is a syntrophic process involving the activity LCFA-degrading bacteria and hydrogen-utilizing methanogens. If methanogens are inhibited, other hydrogen scavengers needed to achieve complete LCFA degradation. In this work, we developed two different oleate (C18:1 LCFA)-degrading anaerobic enrichment cultures, one (ME) another which methanogenesis was inhibited (IE). Inhibition attained by adding solution...
To determine the sensitivity and specificity of liver stiffness measurement (LSM) serum markers (SM) for fibrosis evaluation in chronic hepatitis C.Between 2012 2014, 81 consecutive C virus (HCV) patients had METAVIR score from biopsy compared with concurrent results LSM [transient elastography (TE) [FibroScan®/ARFI technology (Virtual Touch®)] SM [FIB-4/aspartate aminotransferase-to-platelet ratio index (APRI)]. The diagnostic performance these tests was assessed using receiver operating...
The amount and composition of the essential oil from leaves Hypericum androsaemum L. cultivated in Arouca (Portugal) were determined six samples harvested during 1 year at intervals 2 months. seasonally dependent content ranged 0.7 mg/g biomass dry weight September to 3.4 February. contained more than 80 compounds, 70 which (constituting 88-93% total oil) identified by GC GC-MS. An approximation absolute quantification each compound class was performed using a method with an internal...
Between 50% and 86% of patients with autoimmune hepatitis (AIH) relapse after immunosuppression withdrawal; long-term is associated increased risk neoplasias infections. Chloroquine diphosphate (CQ) an immunomodulatory drug that reduces the flares in rheumatologic diseases. Our aims were to investigate efficacy safety CQ for maintenance biochemical remission AIH a double-blind randomized trial define subgroup obtained greater benefit from its use. A total 61 histologic (90.1% type 1 [AIH-1])...
The essential oil yields obtained by hydrodistillation of the aerial parts Hypericum androsaemum cultivated plants varied from 0.94 to 4.09 mg/g biomass dry weight, depending harvest time. respective analyses performed gas chromatography and chromatography−mass spectrometry revealed more than 80 compounds, 72 which were identified. Most compounds sesquiterpene hydrocarbons, which, time, corresponded 43−78% total oil. other distributed as monoterpene oxygen-containing sesquiterpenes,...
Inflammatory bowel disease (IBD) is associated with complications, frequent hospitalizations, surgery and death. The introduction of biologic drugs into the therapeutic arsenal in last two decades, combined an expansion immunosuppressant therapy, has changed IBD management may have altered profile hospitalizations in-hospital mortality (IHM) due to IBD.To describe from 2008 2018 analyze IHM 1998 2017 for Brazil.This observational, retrospective, ecological study used secondary data on Brazil...
Summary Glycerol‐rich waste streams produced by the biodiesel, bioethanol and oleochemical industries can be treated valorized anaerobic microbial communities to produce methane. As current knowledge of microorganisms involved in thermophilic glycerol conversion methane is scarce, glycerol‐degrading methanogenic were enriched. A co‐culture Thermoanaerobacter Methanothermobacter species was obtained, pointing a non‐obligately syntrophic degradation. This hypothesis further studied incubating...
Long-chain fatty acids (LCFA) are common contaminants in municipal and industrial wastewater that can be converted anaerobically to methane. A low hydrogen partial pressure is required for LCFA degradation by anaerobic bacteria, requiring the establishment of syntrophic relationships with hydrogenotrophic methanogens. However, high loads inhibit methanogens, hindering biodegradation. Because it has been suggested these compounds may enhanced presence alternative electron acceptors, such as...
ABSTRACT BACKGROUND: Copper deficiency has been linked to alterations in lipid metabolism and hepatic steatosis. Oxidative stress plays a role the pathogenesis of non-alcoholic fatty liver disease (NAFLD). One enzymes that neutralize oxidative is Cu/Zn superoxide dismutase, which depends on availability adequate amounts copper. OBJECTIVE: Correlate levels ceruloplasmin non-ceruloplasmin-bound copper (NCBC) with clinical, biochemical histological parameters (NAFLD) patients. METHODS: Data...
The standard therapy for some autoimmune diseases consists of a combination corticosteroids and thiopurines. In non-responders to thiopurine drugs, the measurement metabolites azathioprine, 6-thioguanine, 6-methylmercaptopurine, can be useful tool. has been used during treatment inflammatory bowel and, less commonly, in hepatitis. Many patients preferentially metabolize thiopurines 6-methylmercaptopurine (6-MMP), which is potentially hepatotoxic, instead active immunosuppressive metabolite....
Essential oils of lime (Citrus aurantifolia) whole fruits and lemon limon) peel from Nigeria have been analysed by combined GC GC-MS. Both were similar composition, but with differences in yields components. The are composed largely monoterpene hydrocarbons (C. aurantifolia 71.6 %; C. limon 81.2 %) oxygenated monoterpenes 23.4 16.7 %). Limonene was the major component oil (65.4 %), while limonene (43.1 ß-pinene (14.2 characteristic oil. Other such as γ-terpinene, α-terpineol,...